Āpiha Antiplatelet: rārangi o raau taero. Anticoagulants me āpiha antiplatelet, ratou āhuatanga

Hua toto maha ai Thrombosis, e tika ana ki te mau hopearaa kino, tae atu ki te mate. mua Pūtaiao tukua whakaora ora o te tūroro ki te taua disorders tika ki tiaki therapy rite te fariiraa i taero antiplatelet.

He aha e anticoagulants?

āhuatanga Rheological o toto ki te patu i te toenga i waenganui i ngā pūnaha coagulation me anticoagulation. I roto i te pupuri i tenei toenga rite te anticoagulant tūturu wāhi antithrombin III me heparin, e whakahaerehia ana tika mahi antithrombotic, ko e, te ārai i te hanganga o te katinga toto. e pā ana te tikanga o te mahi o te muri kei te ki te hanga i te matatini ki antithrombin III, hua i roto i te hanganga o te antithrombin kaha. Ia, i roto i te tahuri, te kawenga mō te here ki thrombin, hanga hohekore reira - wāhi reira ki inhibition o thrombus hanganga. Antithrombin III iho hoki he āhuatanga anticoagulant mā te inactivating thrombin, Heoi, puta te tauhohenga rawa āta.

Ko te kaha o te heparin ki te whakarite inactivation o thrombin tei runga i te nui o antithrombin III i te toto. hiahiatia whakarerekētanga horopeta e hiahiatia ana te hāngai i runga i te tātari. E mea pinepine e rapu te whakarite o te raau taero e rua i kotahi - heparin me antithrombin III, i te inenga ano e tīpakohia fakafo'ituitui mo te tangata ia.

Ka herea e ki antithrombin - e kore e anake te mahi o te heparin. I tua atu, e taea ki te wahia iho pūtōtepe waho te whai wāhitanga o te plasmin ia, kua karangatia e lysis kore-enzymatic. Tenei tauhohenga Ko te hanganga o te pūhui ki te momo o matū kaha biologically, tae atu ki ngā peptides me hormones. I roto i te tahi atu āhuatanga wehewehe te pehanga o te maha o whākōkī whai wāhi i roto i te tukanga inflammatory (whakaiti tona kaha), me te te faaitoitoraa o te lipoprotein lipase me te whakapai ake i te rere toto i roto i te oko ngakau.

He aha te mea te āpiha antiplatelet?

Teuteu anticoagulants E tōtika me māngai antiplatelet whakamahia i roto i te rongoā. riro tenei ingoa nga moni, e tautāwhi i te honohono (whakawhāititanga) o ngā pūtau toto - pūtau toto whero me platelets. Ko rerekē, i whakaaetia e rave rahi rōpū te tikanga o te mahi o enei matū. āpiha Antiplatelet, rārangi whānui o raau taero e Whakaröpütia e whai ake.

1. te raveraa ra konupūmā ( "Verapamil").
2. inhibitors whākōkī, e ngā matū e pehi i cyclooxygenase (waikawa ahipirini, "naproxen", "Indomethacin") me te cyclase adenylate me phosphodiesterase ( "Ticlopidine", "Pentoxifylline").
3. Drugs e whakaongaonga te hanganga o te prostacyclin ( "pirazolinov").
4. Prostanoids ( "Prostacyclin" me ona analogues o te take mai waihanga).
5. Drugs e pehi i te rere o ngā matū i roto i roto i te platelets ( "Pyracetam").

iteraa papû

raau taero Antiplatelet - taero nei ingoa e mohiotia ki he tokomaha e tika ana ki te tono whānui. Ko te mahi matua o tenei rōpū - o prophylaxis Thrombosis. raau taero Antiplatelet - raau taero e tōtika te tono i roto i te maha o pathologies Cardiovascular, me te i muri i te pokanga (vaolo ngakau prosthetic).

āpiha Antiplatelet: rārangi o raau taero e whakamahia nuitia i roto i te mahi hauora

Drugs e no ki tenei rōpū, tino he rota, a ka whai ratou katoa ratou ake peculiarities. Tīpakonga o te tarukino tei runga i te take haumanu. A, o te akoranga, whaiaro rongoā-i roto i tenei āhuatanga he tika.

"Ahipirini"

I roto i te ture o eicosanoids hemostasis e whai wāhi nei ko te hua o te piti hāora o te waikawa arachidonic. I roto i te nui tino o thromboxane A2, me tona mahi matua - te whakarite mōtepe whakahiato. whakahaua te mahi o te ahipirini te ki inhibition o te pūmua whākōkī, ka karanga cyclooxygenase. Ka rite ki te hua o tenei kōtuitanga tāmia te tomboksana A2, koia leva tukanga hanganga thrombus. faarahi te pānga-tango anō i te tarukino, i te tika ki te whakaeminga. Hoki te inhibition oti o cyclooxygenase hiahiatia te horomanga ia. Te inenga tino arotau te whakaiti i te tūponotanga o ngā pānga taha, "ahipirini" ara ki te whakamahi tonu. Ko Kāore horopeta mārō, mai i reira ko te mōrea o te toto pōauautanga.

"Ticlopidine"

hāngai ana te raau taero e runga ārai etahi receptors e he kawenga mō clots toto. Nuinga, ka hono ia koutou ki a ratou i reira he whakaongaongatia he huringa o ADP mōtepe whakawhāititanga me ahuahu, a "Ticlopidine" inhibits tenei tukanga. He āhuatanga o te kaihoko antiplatelet ko te bioavailability tiketike, tutuki nei i te momi tere tiketike. I muri whakakore pānga e kitea noa hoki 3-5 ra. Ko te drawback ko te maha nui o ngā pānga taha, tae atu ki te whakapairuaki noa, korere, anemia me agranulocytosis.

"Clopidogrel"

āpiha Antiplatelet rite ki te momo o te mahi ko rite ki te "ticlopidine", engari tona painga ko te tāoke āhua iti. I tua atu, ko te nui raro te mōrea o ngā pānga taha, ina tango i tēnei tarukino. I reira nga tohunga hoatu hiahia ki "clopidogrel" e tika ana ki te ngaro o pōauautanga pērā i agranulocytosis me thrombocytopenia.

"Eptifibatide"

Te raau homai whakawhāititanga mā te ārai i te glycoprotein, kei nei i roto i te membrane mōtepe. Whakaritea mo te bolus rō-uaua, te tikanga i roto i te angina me angioplasty ki te whakaiti i te tūponotanga o te infarction myocardial.

"Dipyridamole"

Ko te pānga matua o te tarukino - vasodilatation ti'aturi, arā te roha o oko toto, engari faaite pānga antiplatelet te kitea ka ngā ki ētahi atu taero. "Dipyridamole" whakaritea ki "ahipirini", ki te mea i reira te mea he mōrearea nui o clots toto. Ko reira taea hoki ki te ngā ki te "warfarin", e te tōtika tono i muri i te piha ngakau prosthetic ki te whakaiti i te tūponotanga o embolisms. I roto i te monotherapy Ko iti korerotia pānga.

raau taero Antiplatelet - taero (te rārangi: "Elikvis", "clopidogrel" me etahi atu), Kei te whānui e whakamahia ana i roto i te mahi.

contraindications

titau Wāhui o therapy antiplatelet hītori tupato, e ngā pārongo i runga i comorbidity. I roto i te aroaro o te mate e te mea he contraindication mo te fariiraa i te raau taero i roto i tenei rōpū, he ako o te mahere maimoatanga. I roto i ngā take pēnei i, kawea te kōwhiringa o raau taero takitahi me o ratou toketaá, me te maimoatanga i roto i raro i te tirotiro tino hauora. I roto i kore take e he whakarite motuhake o āpiha antiplatelet, no te mea te mau hopearaa e taea e auha.

Ko te rārangi o contraindications:

• mate pāwera;
• hemorrhagic diathesis;
• te mōrea o te toto;
• ate nui, me te tākihi iti hoki;
• hītori o te arrhythmia;
• takawhita, nui;
• mate taunutia o te pūnaha romahā;
• tau o ngā tamariki (mo te nuinga o ngā hua).

I tua atu, he tokomaha o āpiha antiplatelet (te rārangi o ngā hua arotakengia i roto i tenei tuhinga) e contraindicated i roto i te hapū, me te hohipera. I roto i tenei wā, kia pai taero e te hunga haumaru mō te tamaiti, me te mo te whaea.

āpiha Antiplatelet. Drugs: he rārangi o hapūtanga

Ki te ofati koe te tohanga fetal te mōrea o te materoto. huaina ana tēnei āhuatanga ko te iti hoki fetoplacental. Ki te ofati koe te tuku o te hāora ki te toto o te kukune whakawhanake hypoxia kino, e fakamanamanai te rerekētanga e kore anake i roto i tona whanaketanga, engari ano hoki te mate. Tātarihia te he māuiuitanga titau, no te maimoatanga wawe, e ngā i roto i te whakapai ake rere toto, whakaiti i te pokey toto. Hoki tenei a whakaritea āpiha antiplatelet, Heoi, kia mōhio e he haumaru i roto i te hapū e kore nga taero katoa i roto i tenei rōpū. Taea ki te whakamahi anake etahi o nga moni.

"Kurantil"

Ko te tino hira te tarukino tika ki te meka e i roto i tona rārangi o contraindications kahore hapūtanga me te ū. whakauru Hohe "Chimes" - dipyridamole whakaahuatia i mua, e dilates oko toto, me te inhibits thrombus hanganga. whakapiki i te reira i rere toto myocardial, whakarite i te tuku o te nui e hiahiatia ana o te hāora. I roto i tenei ara, K "Urantia" taea te whakamahi i roto i te aroaro o te mate Cardiovascular i roto i nga wahine hapu. Heoi, ko te tohu matua mō te hapu ko reira kore placentofetal. Na roto i te whakapai ake i ngā āhuatanga rheological o toto me te vasodilatation, oko ārai tanumia o te ewe, na e kore e tukua e te kukune i te hypoxia. He painga anō o te tarukino taea te huaina pānga immunomodulating. Ko te raau whakaongaonga te hanga o te interferon, reira whakaiti i te mōrea o mate viral i roto i te whaea. Ahakoa "Kurantil" me reira e taea te whakamahi i roto i te hapū, me te hohipera, engari kia whakahau anake reira, ki te tohua. I tango i te raau taero e whakaiti i te kohi o te ti e te taofe rite te whakaiti ratou tona whai huatanga. raau taero Antiplatelet - taero (rārangi i runga) e kore e kia ngā ki te inu taua. Ahakoa kore te hapūtanga tohutohu ratou ki te tiki wāhi i roto i tetahi ara.

āpiha Antiplatelet, he rārangi o raau taero e ngā pinepine o ingoa, kei te whakamahia tōtika i roto i te maimoatanga o mate o te pūnaha Cardiovascular. Heoi, kia mōhio o te pōauautanga taea e pā ana ki pokey toto heke me inhibition upoo-. raau taero Antiplatelet - raau taero e taea te whakamahi anake i raro i te te tirotiro o te rata haere, ka tangohia e ia ake te inenga tika, me te akoranga o te maimoatanga.