Drugs mō te migraine - triptans. Dosing me ngā āhuatanga o te mahi

Migraine - Ko tetahi o nga mate tino noa, e taea te whakaiti i te tōtika o te tūroro maha tenei. pā ana tēnei mate e pā ana ki 6% o nga tangata me te 18% wahine. Ko tino nui ēnei whika. Heoi, 60% o te iwi e mamae i tenei mate, takitahi tango ngā Pë mō te mamae. Ka rite ki te tikanga, taua mahi anake whakahōhā te akoranga o te mate.

Mea atu kahore Pë

He tokomaha te iwi e mamae i migraines, kahore e mohio me pehea ki te mutu whakaeke, a te mutunga o rawa ki te tango i painkillers. Mai i tenei pānga maimoatanga he iti rawa. te ngaro ia ranei. Tenei ai e tīmata te manawanui ki te whakapiki ake i āta te inenga o te rongoā. Ka rite ki te hua o taua mahi whakanui i anake te mōrearea o te kino tākihi, te whanaketanga o te gastritis. I roto i ētahi wā, ka taea e Pë horomanga arahi ki fifi atu nui - te putanga o pāhoahoa tarukino-piri.

Ko te aha, ki te whai koe i tetahi tohumate o migraine kia tirohia ki tohunga. Whaiaro-rongoā i roto i tenei take, ka taea e anake whakahōhā huru o te manawanui. I roto i te mutunga o te rau tau 19 i hanga rōpū katoa hou taero antimigraine - agonists whiriwhiri o 5 NT 18 / D-receptors. Taua matū he pärönaki o 5-gidroksitritamina. Haapotohia to ratou ingoa - triptanity. Drugs mō migraine tenei whakatupuranga, ko te nui ake pai atu i Pë tikanga. I tua atu, riro enei taputapu atu wātea ki ngā kāwai katoa o tūroro.

Kia pehea te mahi taero

Triptans - te maimoatanga tino matatau mō tenei mate kino, migraine. Kei te whakapono te reira e enei taero katoa mahi te ara ano. Heoi, tauturu kotahi manawanui he torutoru noa o te maha nui o triptans. Na reira, ko te kōwhiringa whakamutunga o tenei hua tonu anake ki te manawanui. Hei whakatau i te tōtika o te triptane ngā, e tika ana ki te whakamatautau i te tarukino i roto i whakaeke migraine. I te iti rawa kia haere toru o ratou. Ki te mea kua awhinatia te tarukino, taea te whakamahi i te reira i roto i te heke mai. O te akoranga, ka taea e te whiriwhiri nui pā te utu o te triptan. I muri i te katoa, e kore e cheap enei raau taero. I tua atu, i ia waihanga he tetahi pānga analgesic. I tua atu, he mea e tika ana ki te mohio he aha e nga triptans mo migraine, āhuatanga mahi, tikanga o te fariiraa me contraindications.

Tuatahi o te katoa, taua raau taero i te mana i runga i te taiepa receptors oko. rite te hua ai reira whāiti dilated oko toto kaka, me te āwhina ki te whakaiti pāhoahoa.

riro taua mau faaineineraa i te selectivity makona tiketike. Ko te aha triptans i te pānga i runga i oko toto Rura. Ko tēnei ko te kotahi o ratou tino. Heoi, kahore o ratou pānga i runga i nga oko piringa, me te coronary. Me kï reira e triptans - taero migraine e ārai i te takanga o te mamae i te taumata receptor, e kei i roto i te karihi filosilivá o te karere trigeminal. Tenei nui te whakaiti tūtohutanga ki te mamae.

I tua atu, ka taea e enei taero whakaiti te auau o relapses, me te ake tōtika faaore tohumate hāngai, pērā i te tangi, me te photophobia, ruaki me te whakapairuaki.

Mara o te mahi o triptans

Ki te mārama me pēhea te mahi i enei taero, ko ki te whakarato i te taketake:

1. Vasoconstriction, kei roto i te roro.
2. mahi Anti-inflammatory: whakaiti o ngawhatanga, e e pēhanga i runga i te mau hopearaa io.
3. Tukino hiamo karere trigeminal me whakaiti i tona tūtohutanga ki te mamae.

Ka rite ki a koutou e taea te kite, triptans hoki migraine - te raau taero whai hua tino e taea te aukati i patua o te mate. Ko te mea matua ko te ki te whiriwhiri i te tarukino tika

Huapai me ngā huakore o triptans

I roto i nga painga o taua hua ko ki te whakarato whai hua te whakahaere o te mamae me te tohu e pā ana, mahi tere. I tua atu, ka taea te whakamahi i te triptans mo te maimoatanga o te mate i roto i te rerekē ngā kāwai tau.

O te akoranga, he huakore tetahi tarukino. Tino tauturu i triptans mō migraine me te ānini. Heoi, kei te tonu e kore i matau tino te tūāwhiorangi o te mahi o enei taero. I tua atu, e taea ki te tango i triptans rite ratou hauora kore katoa te mea. Kei te riria te reira ki te whakamahi i enei taero mō te iwi e mate ana i te mate ngakau coronary. I roto i tenei kāwai ko te hunga e whai i te clots toto me te takawhita mārere he reira.

Ko te whakatupuranga tuatahi

taka migraine - triptans - herenga wehea ki te maha ngā rōpū. Ko te tuatahi, me te tuarua o nga whakatupuranga tenei. He ona ake huapai me ngā huakore ia tarukino. Na, ko te whakatupuranga tuatahi o pono "Sumatriptan". Ko te tarukino tuatahi tenei. Ia i matau tata rawa ka ko te ahua o te paerewa i roto i te maimoatanga o te migraine. I roto i te mau tamataraa haumanu ka mau te reira whai wāhi 60 mano iwi. Hoki te wā tuatahi i kitea te raau taero e GlaxoSmithKline i 1989.

Fele "sumatriptan" mohio te i roto i te puka o papa tikanga, papa pani, me te rehu. mahi ia o ratou ōrite. Te pānga mōrahi i muri i tango i te pire puta i muri i te hawhe e rua me haora, me te rehu - 90 meneti.

whakatupuranga tuarua

He maha - Triptans - taero mō te migraine, no ki tenei rōpū. I tua atu, e kore e makona haapii ratou. Hua i ratou i roto i te puka o papa. I roto i te whai hua tino e:

1. "Natriptan" - Kua te pānga kua kitea hoki e pā ana ki te haora i muri i ingestion. heke Pain te. puta pānga mōrahi i roto i te torutoru haora.
2. "Frovatripan" - ko ahua ngoikore tenei tarukino, engari riro te reira iti kitea pānga taha kino.
3. "Zolmitriptan" - mahi i muri i te 15 meneti i muri i whakahaere. tutuki ana te pānga mōrahi te i muri i pā ana ki te haora. Ko te tino pai tenei tarukino ki te patu i te tihi.
4. "Rizatriptan" - rite ki te faaineineraa o te whakatupuranga tuatahi, engari kua he pānga atu korerotia.
5. "Almotriptan" - he pai ki te "Sumatriptan" e rave rahi mau taime i runga i te tōtika i tēnei tarukino. tutuki ana te pānga mōrahi te i muri i 1.5 haora.
6. "Relpaks" - he atu mōna i roto i ngā o te pānga i runga i oko toto o te roro i tēnei tarukino. Ahakoa he tino rite ki "sumatriptan" te mahi.

Drugs mō te migraine (triptans): utu me ngā tūtohutanga i runga i fariiraa

Ki te hanga te reira mārama atu e tīari taero, tapaea tatou he tepu:

āhuatanga fariiraa

Na, me pehea pai ki te tango i triptans mō migraine me te ānini? Tohutohu i roto i tenei take e te āwhina ki te whakatau i te inenga me te wa o te whakauru. Ko te mea matua - mahara e roto i te take o te mamae e faarahi āta me e kore e whai te āhua o migraine, tango rongoā pērā hanga kore tikanga he mahere. I roto i tenei take, kia tangohia e koe he analgesic kore-motuhake. Ko te tino nui tenei. Tikanga, kia triptans kia tangohia i muri i te mutunga o te koreutu, kahore i muri atu i te rua haora i muri i te tīmatanga o te hūhi ranei. I tua atu, ka taea te whakamahi i te migraine triptan me ki ētahi atu taero, pērā i metoclopramide domperidone ranei.

Ko te rehu, kia whakamahia ratou i te whakapairuaki makona korerotia a, o te akoranga, ruaki. "Imigran" taea te tangohia ki te whakakore te mana migraine. Ka taea te whakaritea Triptanity ki te whanaketanga o te mate e kore e anake, engari ano hoki i roto i te wā i waenganui i whakaeke i roto i te tikanga ki te ārai. tukua ana tēnei i roto i te wā, no te:

1. Kua heke te kounga o te manawanui o te ora.
2. He tino uaua ki te hamani NSAIDs.
3. atu pinepine atu i te whakaeke migraine puta rua i roto i te 30 ra.

Ki te mahi ki te ānini

Hei tango i te whakaeke migraine, he mea e tika ana ki te tuatahi tamata ki te tango 1,000 milligrams waikawa ahipirini, he kawhe inu reka kei roto, 10 milligrams o te tarukino "Motilium" ranei. Ki te haere tonu i muri i 45 meneti te ānini, he reira taea ki te whakamahi i te triptan.

Me kï reira e i roto i ngā āhuatanga i reira hoki e toru whakaeke kihai i hoatu e analgesic nonspecific te hua e hiahiatia ana, ka taea e te tango tonu koe i te rongoa mo te migraine. Ki te reira ko te koreutu, te whakamahi o te ahipirini utu i muri i anake kua tīmata reira, a i muri i te takanga o te mamae - taero mō te migraine (triptans).

He aha te ki te hoki mai te mamae?

Tata 50% o tūroro i reira ko te hoki o te ānini i roto i te torutoru nga ra. Tohunga tūtohu e i roto i te āhuatanga i taua tango ano rongoā mō te migraine - triptans. Kia mahara te reira e pā ana ki te horopeta mōrahi rā o te tarukino. Mau ia i te tarukino he kahore mua atu i te rua haora i muri i te pire tuatahi. Ki te taea te nohotahi te ānini, kia whakakapi i te manawanui triptans analgesic nonspecific.

E tano ia tapao e maha e kitea te hoki hūhi i roto i te tūroro ki te pāngia ka makona ratou roa e taea muri i waho tango mamae rongoā mō neke atu i te 24 haora. Ahakoa i tango tetahi auau triptan o taua mau ohipa kua noho tata tonu. Heoi, e whakapono ana tohunga e te whakamahi o "Eletriptan" me "naratriptan" tauturu whakaiti i te maha o whakaeke hou.

Ki te kahore he hua

He wā ka kore e hoatu e taero mō te migraine (triptans) me taero kore-motuhake te hua e hiahiatia ana, me te kore e faaore i te mamae. I roto i tenei take, ka taea e te tākuta whakahau te therapy matatini, e Kei roto whakahaere taero anticonvulsant, me te B-blockers. Ēnei taero ngā "nadolol," "acebutolol", "penbutolol", "Labetanol", "Betaxolol" me etahi atu.

pānga te taha o triptans

taea ēnei taero e tangohia 10 anake ra te marama. Kore, kia wheako koe etahi raruraru. whakamahi More auau o triptans taea arahi ki ānini, e puta i roto i ngā tūroro i te fariiraa i te tarukino. I tua atu, pērā i taero mahi i ngā pānga taha, tae atu ki:

1. He mana'o o te mahana, me te pakeke i roto i te wahi, te momoe, rohirohi, whanoke, tūtohutanga.
2. puku myocardial ranei kōateate, colitis rere pūroto, hemorrhagic korere, mangai maroke, mamae puku, me te whakapairuaki.
3. Myalgia me uaua ngoikore.
4. vasospasm coronary, infarction myocardial, angina pectoris, tachycardia, palpitations.
5. Polyuria, me urination auau.
6. Anaphylaxis, angioedema, urticaria.

Ahakoa tenei katoa, triptans hoki migraine - he rongoā tere-mahi. Ki te tangohia e koe taero tino whakarite i ki tohutohu, na kahore raruraru. Ko te tino ngoikoretanga anake o taua rongoā - utu. Ka taea e kore katoa te utu ki te hoko i te tarukino taua.