Antimicrobial TSifran. Mahinga Drug

Medicine "TSifran" ko he māngai antimicrobial ki te whānui o te mahi, me te no ki te rōpū pharmacological o fluoroquinolones. wāhanga Active o te tarukino he ciprofloxacin me tinidazole. Nā ki te pehanga o te gyrase DNA me te kitakita inhibition DNA kōtuitanga, he mātātoa tino hoki te nuinga o microorganisms karamu-kino enei matū kaha.

I roto i ngā, i te mahi o te mahi bactericidal o te faaineineraa "TSifran" tuhipoka ako ā-ki te faatura ki enei huakita: Neisseriagonorrhoeae, Neisseriameningitidis, Haemophilusinfluenzae, Pseudomonasaeruginosa, Salmonellaspp, Escherichiacoli me ētahi atu microorganisms taumahatanga whakaputa me kore whakaputa penicillinase, me te taumahatanga methicillin-ātete ko Enterococcusspp, Chlamydiaspp, Mycobacteriumspp, Legionellaspp ... taumahatanga.

mahi pharmacological o bactericidal medicament whanui hihinga "TSifran" tohutohu mō te whakamahi ko e whai ake: ". tikanga te taputapu te mo te maimoatanga o pathologies hopuhopu tōtika i roto i te maimoatanga o ngā tukanga inflammatory - mate whakauru whakapataritari i te mahi o takohe me te anaerobic microorganisms me hātare".

Pharmacokinetics

Ko nga kai kaha o te tarukino "TSifran" tohutohu mō te whakamahi e pā ana ki tino hototahi. Na whai ciprofloxacin me tinidazole absorption pai i roto i te wahi gastrointestinal.

Whakaaro i ia o nga kai kaha o te tarukino, kia tuhia te reira e ciprofloxacin kua pā ana ki 70% bioavailability. pakanga Ko tōna absorption te ahua, i te whakamahi o te kai. Tenei raau He uruhanga pai ki te kopa me fluids tinana, tae atu ki te wheua, uaua, ngako, me te wheua ngohe kiko. ô i ia ki whēkau o te pūnaha mimi, tae atu i roto i te tinana pērā i te repeure. Ko te mea ngaro heheu te reira i te ihirangi kiprofloksatsina kukū tiketike, rite, te mea, a roto i purapura moenga, huware, ate, waitinana wai, hūpē.

Tinidazole bioavailability pūmau rerekē. hoki taka tere tenei wāhanga i nohanga tiketike i roto i te kikokiko o te tinana tangata wai te ô i reo, i roto i ngā i roto i te inu cerebrospinal, hāngai nei i roto i te taua rite i roto i te taumata wē. Mō te hauwhā o te nui o ngā matū ingested excreted i roto i te mimi tonu, tukua e pā ana ki 10% i roto i te puka o metabolites, rau wahi tino iti o te wāhanga te tinana i roto i te tütae.

Tuhinga mō te tarukino "TSifran" tohutohu mō te whakamahi e pā ana ki te maimoatanga whakauru o ngā tukanga hopuhopu. I roto i te pathologies motuhake ake, mo te maimoatanga o te tarukino i raro i whakaaro e whakamahia nei, te mate e whai ake nei:

• te tapû-ma'i ;

• kōtuitui-hopuhopu tukanga inflammatory;

• koripi amoebic me te koripi momo whakauru (amoebic me kitakita);

• periodontitis, periostitis me ētahi atu mate hopuhopu o te kōhao-waha;

• māuiuitanga inflammatory gynecological;

• pakohu kakā ma'i;

• mate o te kiri, me te kopa ngohengohe;

• mate hopuhopu postoperative;

• tana pukapuka whēwhē.

Ko tētahi o ratou, me ētahi atu mate meinga e takohe me te anaerobic huakita tairongo ki te mahi o nga wae tarukino.

faaineineraa tali "TSifran" postprandial. kia Papa tangohia ki te wai i roto i te nui. tūroro pakeke tango i te tarukino rua he ra mo te papa o 500 / 600mg rua 250 / 300mg ranei. Tūroro i raro i te tau o waru nga tau o tau, e kore te te tarukino faaterehia. E kore e tūtohu ana hoki te whakamahi i roto i te hapu.

Contraindications ki te whakamahi o te raau taero whakaahuatia i roto i te therapy ko te tūtohutanga nui ake ki te wāhanga hanga wahi o tsifran me māuiuitanga o toto, porphyria.