"Azarga" (pata kanohi): tohutohu mō te whakamahi, utu, me arotake. He reira te kanohi orotahi roimata "Azarga"?

Nahea te tarukino "Azarga" (pata kanohi)? Ka Tohutohu ki tenei tikanga, ona pānga taha, contraindications me tohu mō te whakamahi e te aroaro i roto i tenei tuhinga. I tua atu, ka ako koe e pā ana ki te mea he āhuatanga pharmacological o tenei tarukino, pehea me i te mea kia whakamahia toketaá, te aha e meatia i roto i te take o te tuwhena rawa, a na i runga i.

tuku Puka tarukino rohe me tona hanganga

I roto i te mea puka tukua te ki te tarukino rongoā "Azarga"? Eye makaka - ko reira anake te ahua o te tuku tarukino. 1 ml o te raau taero kei taua wāhanga hohe rite i roto i te puka o timolol maleate i te nui o 5 mg me brinzolamide (10 mg).

Me mahara hoki käore te reira e mea te "Azarga" medicament ngā huānga pŭpŭ tauturu. Ko ētahi o ēnei mannitol, disodium edetate, konutai waihā, te konutai pūhaumāota, 50% pūhaumāota benzalkonium, tyloxapol me te wai e purea. He arumoni wātea "Azarga" te maturuturunga iho dropper pounamu o 5 ml.

Ko te āhuatanga pharmacological o pata

He aha ngā āhuatanga e te tarukino "Azarga" (makaka kanohi), te ako ki te roto nei i roto i te pouaka kātene tahi me te tarukino? Ka rite ki whakahuatia i runga ake, Kei te medicament aroaro 2 wāhanga kaha matua. Reira timolol me brinzolamide. Ko te whakamutunga, ko te inhibitor o anhydrase carbonic II. Ngā mihi ki reira i roto i te tinana tangata pōturi iho te hanganga o ngā ngota hauwai pākawa, a muri heke konutai me te waka inu. arata'i tēnei tukanga ki te hekenga i roto i te hanga te katakata wai i roto i te tinana ciliary o te okana ataata. Nā tēnei, i roto i te e tukupu ana pēhanga intraocular.

Ka rite ki hoki timolol, ka ko te beta-pūārai e kore e mukākā te pūnaha io pukuaroha, me te e kore e tautāwhi i te uaua cardiac tenei. I muri i te whakamahi rohe, te whakaiti reira te hanganga o te houku me whakanuia ana tona matamua.

Pharmacokinetics o te tarukino

ahakoa te raau taero ko whenumi, "Azarga" (kanohi pata)? Tohutohu ki tenei āhuatanga whakarato e te whakamahi wā o wāhanga kaha pērā i brinzolamide me timolol, taea ki te tomo ki roto ki te tohanga nahanaha e. Kei te riro te taonga whakamutunga ki te erythrocytes i muri i whiriwhiri here ki anhydrase carbonic II. Ko tōna feohi ki pūmua wē he tata ki te 60%.

Brinzolamide metabolized e e-dealkylation, N-dealkylation me hāora o te taha mekameka N-propyl. Kei te whakapae te reira e te whatukuhu i roto i te puka tonu i roto i te nui o te 60%. Ko te kupu 20% mai i te tinana tangata rite metabolites.

wā Timolol momi he 5 haora i muri i te whakamahi wā o te tarukino. Ko te pākia o te taonga e wahi i roto i ara e rua: ethanolamine ki te hanga i mekameka taha i runga i te whakakai thiadiazole, a hoki ana ki te hanga i te mekameka hauota taha te waihā o te morpholine me te rōpū carbonyl hono nei ki te hauota.

E excreted te nuinga metabolites Timolol me i hanga mā te whatukuhu. Te matū Tata 20% he putanga i roto i te puka tonu.

Tuhinga mo te whakamahi o moni

I roto i ētahi wā, te whakamahi i tarukino "Azarga"? E whakaritea pata kanohi i roto i whakaiti teitei pēhanga intraocular, i hanga nei e tika ana ki te whakatuwhera-koki papahewa. Ano, Kei te maha whakamahia te reira i roto i te tūroro ki te takawhita ocular. Ko Ko anake, ki te i monotherapy kua iti ki te whakaiti i te pēhanga tenei.

Contraindications ki te whakamahi o moni rohe

I roto i ētahi wā, e kore koutou e taea e te whakamahi i te tarukino "Azarga" (pata kanohi)? Tohutohu o tenei taputapu kei roto i te rārangi tika nui o contraindications. Whakaaroa reira i teie nei:

• nui haere te tūtohutanga manawanui ki sulfonamides;
• huangō, tae atu hītori;
• Hypersensitivity ki nga wae tarukino;
• taunutia mate pūkahukahu ma'i, e puta rawa pakeke;
• acidosis hyperchloraemic;
• hyperreactivity arahau;
• hypersensitivity ki beta-blockers;
• pakohu bradycardia;
• tau o ngā tamariki (18 tau);
• AV-poraka II me III tohu;
• hohipera;
• kore ngakau (nui);
• i roto i te hapū;
• ru cardiogenic;
• tono tukutahi o inhibitors (waha), anhydrase carbonic;
• Rhinitis pāwera, e rerengia ana e tino uaua;
• katinga papahewa;
• nui iti hoki tākihi.

rongoā tango tūpato

Na e matau ana koutou, i raro i tetahi ine kore e tūtohu ana ki te whakamahi i te rongoa, "Azarga". i runga i te tono o te aratohu taputapu kei roto ngā mōhiohio e pā ana ki te take i roto i nei kia whakamahia reira ki te tūpato nui. Kei roto i tenei rārangi, tūroro ki Prinzmetal angina, hyperthyroidism, he takahi o te pokapū, piringa disorders circulatory me hypotension.

Me mahara hoki käore te reira e te mea iti mo te maimoatanga o te tūroro ki te pseudoexfoliation me pigmentary horomanga papahewa rongoā. I roto i ngā take pēnei i, kia aroturuki auau pēhanga intraocular.

Me Whakatūpatotanga ki tautapa te tarukino ki te tūroro ki tauhohe anaphylactic. Tenei meka Ko e tika ana ki te meka i taua tūroro te fariiraa beta-blockers, hei ātete ki te toketaá mua o epinephrine i te maimoatanga o tauhohe anaphylactic.

Ka rite ki whakahuatia i runga ake, ki te brinzolamide me te timolol taea amohia e absorption pūnahanaha. I roto i tenei take, kia te wāhanga tuatahi meinga pānga taha ki te pūnaha, ngakau me te toto oko romahā. I roto i tenei hononga, e tūtohu ana ki te aroturuki huru o te manawanui mua ki a te wā maimoatanga.

E whakaritea Beta-blockers ki te tūpato tino i roto i te tūroro ki te mate huka, me te haafifi i ki e suka. Ko e tika ana ki te meka e taea ngāwari enei moni huna kanohi i te tohu o te suka whakapeka tenei.

I mua kia pokanga beta-blockers kia poua atu (mō te 2 ra). Oia mau, i roto i te rehunga whānui, e taea ki te whakaiti i te tūtohutanga myocardial ki whakaongaonga (kaungāongo'i), e mea faufaa no te mahi ngakau ratou.

Drug "Azarga" e arotake ka aroaro i raro, kei reira brinzolamide i te mea he sulfonamide. Hoatu e te whakamahi wā puta absorption pūnahanaha o te medicament, kia whakaatu tūroro tauhohe kino e te hunga angamaheni mo enei matū.

pānga taha

Eye makaka "Azarga", te utu o te mea tiketike nui ki te whai i te whānuitanga o ngā pānga taha. whakaahua tatou ratou i roto i te kōrero atu.

• tūroro Local urupare ki te tarukino. I roto i te 10% o ngā take i roto i te tūroro ki te hyperemia tohua conjunctival, horo Corneal, kanohi maroke, kite te peroo, ritenga o nga whekau ataata, me te sensation tinana ke. I roto i te kite 1% o tūroro punctate keratitis, rere kanohi, pīkaru pāwera, itchiness i te kanohi, te mamae kanohi, effusion ki te ruma mārōrō, blepharitis, hūhi i te titiro, crusting i runga i nga taha o nga kamo, erythema o nga kamo, me te kanohi-riaka.
• pānga taha pūnahanaha. I roto i te 10% o te wā i reira he dysgeusia, me te 1% - hekenga i roto i te pēhanga toto, ohoroa, rhinorrhea, taunutia mate pūkahukahu ma'i, tupu makawe waimaero, mamae i roto i te pū māngai, planus pukoko, me mare.

Me mahara hoki käore te reira e te taonga kaha taua, pērā i brinzolamide, kia meinga te rerekētanga e whai ake nei: mydriasis, keratitis, edema kamo, keratopathy, edema kanohi, he hua i roto i te arearenga o te faatae te, whēwhē subconjunctival, he koha o epithelium Corneal, ähua mā karu, nui haere pēhanga intraocular, para i runga i te taupoki io, kanohi tauhohe mate pāwera, te hanganga o hē Corneal, kite waimaero, edema Corneal, pīkaru, nui haere lacrimation, mumura o nga repe meibomian, hypoesthesia kanohi, rua kite, kanohi maroke okonyunktivit, photophobia, pterygium, heke acuity ataata, me te photopsia. I roto i te tuhia ai ngā pānga taha pūnahanaha tau'a, korekore, heke libido, waimaero mahara, ri'ari'ai, motor pōrearea, somnolence, pau te, mate wareware me disorders o te CNS.

Hoki te maimoatanga o tetahi pānga taha te whakamahi i therapy tautoko, me te symptomatic. kia horoia tonu te reira ki te kanohi te wai matao.

Drug "Azarga" (makaka kanohi): Tohutohu

kia rerekē te utu o tenei tarukino, i runga i te whatunga rongoā rānei. Hoatu kia anake te tarukino kia tuku rohe. I mua i te whakamahi, kia kaha ruru te oko.

I roto i te inenga o te pata "Azarga"? Tohutohu ki tenei āhuatanga kei roto ngā mōhiohio taipitopito i runga i tenei kaupapa. E ai ki reira, he tarukino faaterehia kotahi te maturuturunga iho i roto i ia kanohi pūwhera conjunctival. Hei kawe i tenei tikanga, ko te reira e minaminatia ki te rua ra.

I roto i te tikanga ki te karo i te whanaketanga o ngā pānga taha pūnahanaha i muri i te whakamahi i te tarukino e tūtohu ana ki te pēhanga maihao marama kokonga roto o te kanohi (i roto i te rohe ngä o te pūwhera lacrimal). kia muri he tukanga pērā hoki i te iti rawa e rua meneti. Tenei tino whakaiti nga tikanga absorption nahanaha.

Ki te mea kua kua ngaro te whakamahi o te rongoā, kia tonu te maimoatanga i runga i te hōtaka ki te horopeta i muri. I tenei horopeta i roto i tetahi take e kore e nui kotahi te maturuturunga iho i roto i ia pūwhera conjunctival rua he ra.

I roto i taua take, ki te whakakapi te tākuta he rongoā tarukino papahewa "Azarga", e tūtohu ana ki te whakamahi i anake te ra i muri.

tuwhena rawa

I tēnei wā kua korerotia kua tetahi mōhiohio i runga i te wā o te tuwhena rawa. Heoi, i roto i taua mau huru ohipa, i reira te mea he tūponotanga o ngā pānga taha nui haere.

Ara ka whakamahi i te raau taero, arotake

He aha ngā āhuatanga i makaka kanohi "Azarga"? He tino rangirua te Tūroro kōrero e pā ana ki a ratou. Hei tauira, i roto i te paari inhibitors anhydrase carbonic, e kua whakamahia-waha, kia tika pā i te kaha ki te kawe i te mahi e titau nui ake ruruku aro ranei. kia tenei pānga kia tangohia ki whakaaro ina faaue te tarukino ki taote.

I roto i te whakamahi wā o te raau taero i roto i te tūroro e kakahu arotahi whakapā, he mea e tika ana ki te aroturuki i te mana o te taupoki io. Ko e tika ana ki te meka e maha arahi inhibitors anhydrase carbonic ki te rangirua o tona hydration tenei. I mua i te tono i te arotahi te tikanga e tūtohu ki te tango. Tāuta ratou hoki desirably kore mua atu i ¼ haora i muri i te whakamahi o te raau taero.

E kore e tūtohu ana ki te pa ki te pito o te pounamu ki tetahi mata. Te kore e tupu te reira contamination. I muri i te whakamahi i te rongoā dropper kia tonu e kati ana ki raro.

Ngā pāhekoheko ki ētahi atu taero

Kia pehea te nui Ko nga kanohi pata "Azarga"? Ko te tino nui to ratou utu. Ka taea te hokona ētahi mekameka rongoā taua faaineineraa mō tono wā i 950-1050 moni Russian.

Ki te whakamahi tukutahi o te tarukino me te waha inhibitors anhydrase carbonic (hei tauira, taero "Diakarb", "Sulfadiurin", "Fonurit", "Glaupaks", "Dilamoks" me pera i runga i.) Kia whakanui ake ngā pānga taha pūnahanaha.

Ki te tūpato tino ngā tenei taputapu ki troleandomycin, ketoconazole, ritonavir, itraconazole me clotrimazole.

He he he pea taonga mahi hypotensive me whakapōturinga o auau ngakau ki runga ki te taenga o te pūmotu hohe - timolol - ki blockers hongere konupūmā (hei tauira, taero "Verapamil," "Amlodipine" "Diltiazem", me pera i runga i.), Beta-blockers, guanethidine, parasympathomimetics, glycosides cardiac me māngai mo te maimoatanga o arrhythmias cardiac.

Whakaitinga i roto i auau ngakau kitea ki te whakamahi tukutahi o matū quinidine cimetidine ranei.

eyedrops tairitenga "Azarga"

Tata taero katoa i ratou analogues. hanga tenei e kore e taea te reira ki te aukati i te maimoatanga o te mate tīariari ara i roto i te ngaro o te rongoā whakaritea e te tākuta.

Na he aha te mea te orotahi o makaka "Azarga" kanohi ko te pai? He whakahoki mārama ki tenei pātai ko te tino uaua. I muri i te katoa, he pai i roto i to ratou ake ara rite taero. Ano, kia whai ratou i te tino rerekē ngā pānga taha me contraindications. Na reira, i mua i te tono ia ratou, kia mohio ki te kōrero ki tō tākuta.

Na te aha ki te mahi, ki te taea ki te hoko kanohi te manawanui ko makaka "Azarga"? tonu e taea te kitea tētahi orotahi o tenei taputapu i te rongoā. Ki te mahi i tenei, kia mahara anake koe tona ingoa.

Ko te kupu, he orotahi o te tarukino ngā nga rongoā e whai ake nei (makaka kanohi):

• "Teva-Timolol".
• "Timolol Oftan."
• "Inderal".
• "Duoprost".
• "Arutimol".
• "Ko e Betalmik EU".
• "Bufus Timolol".
• "Timadren".
• "Betoptik".
• "Timolol-Akos".
• "Betoptik C".
• "Timolol-DIA."
• "Betoftan".
• "Timolol-arotahi".
• "Ganfort".
• "Timolol-Betalek".
• "Glautam".
• "Timolol-kainga".
• "DuoTrav."

He aha te tahi atu raau taero e taea te whakakapi i te tarukino "Azarga"? He orotahi o te taputapu me tika ngā i te kai kaha taua i roto ano. I roto i taua raau taero e te whai ake:

• "Timolol".
• "Betaxolol."
• "Timolol-MEZ".
• "Okupres-E."
• "Kombigan".
• "Okumol".
• "Ksalakom".
• "TimoGeksal".
• Eye rā "Oftan Timogel".
• "Ksonef".
• "Optibetol".
• "Niolol" rā kanohi.
• "Ksonef BC".
• "Timolollong".
• "Okuker";
• Eye makaka kahore korotutu "timolol-kainga".
• "Okumed" me pera i runga i.