"Hydrea": ako ā-, arotake, whakaahua, analogues

Drug "Hydrea" no ki te anticancer taero. Te raau e te pānga cytostatic, te huarahi o i hāngai te i runga i te inhibition o DNA kōtuitanga, me te pānga i runga i te ngaro RNA me te kōtuitanga pūmua.

I roto i te mea puka kua hangaia reira tarukino, he aha ngā reira o?

tukua te medicament te i roto i te puka o capsules i hanga e hāngai ana hydroxycarbamide, i te mea 500 mg i roto i ia capsule. He wātea i roto i te oko whakaata (100 capsules), ranei he mōkihi namunamu (10 capsules) te tarukino. O te wāhanga ngaahi houalotú whakamahia stearate konupora me te waikawa citric. Ano, kō atu i te hanganga i te konutai hauwai Phosphate dihydrate me monohydrate reihuka.

Ko te matū e riro te anga o capsules "Hydrea" tohutohu he Titanium hauhā, tae me te gelatin. i hanga te tuhituhinga e te waituhi whiwhi nei e tika ana ki te pūhui o propylene glycol, shellac, waipiro (isopropyl, mewaro ahumahi me N-butyl), me te wai e purea me rino waikura pango.

pharmacodynamics

Ko te tarukino ko te antimetabolite, whakakitea tona pānga kei roto i te wāhanga S huringa pūtau. "Hydrea" taea ki te mutu te whanaketanga o ngā pūtau i roto i te interphase G1-S, i te mea tino nui ka tukutahi ki te fariiraa o te medicament kawea iraruke, pera i roto i te wāhanga G1 e tairongo ki te irradiation pūtau puku. whakarei ake i te faaineineraa i te mahi ribonukleoziddifosfatreduktazoy puta (tuipūmua reductase inhibitor). Na roto i tona whakamahi leva kōtuitanga DNA, engari e kore e fakahohaasi pūmua me te RNA hanganga.

Pharmacokinetics

Absorption o te raau taero i roto i te wahi gastrointestinal whakaahua ana "Hydrea" ā-ako pehea nohopuku i waho te awe e horomanga kai, me te arata'i ki te paetae o te taumata mōrahi o te taonga kaha i roto i te tinana e pā ana ki te rua nga haora i muri i te kai o te tikanga ā-. Ko te medicament haere i roto i te arai toto-roro, āhuatanga e te tohatoha tere hakari i roto i ascites me fluids cerebrospinal. putu te raau i roto i erythrocytes me leukocytes wāhanga excreted roto e toru ki te wha haora. pākia Motunga i roto i te ate. excreted te nuinga o te raau taero e te whatukuhu i roto i te puka o te hydroxyurea, he roanga hi'oraa maitai o tenei tukanga ko ma rua haora. e kore e huri te reira i te tahi mau o tona ahua, nekehia te nui iti te i te tinana i roto i te mimi. Via te tarukino wahi romahā excreted rite te hauhā. I muri i te fariiraa i ta "Hydrea" ako its whakakorenga oti i roto i te ra. Mai haere te wahi matua o te tarukino i roto i te whatukuhu, i roto i tūroro e whai i te māuiuitanga o whekau, whakaiti i te horopeta o te tarukino.

iteraa papû

taea "Hydrea" ako i runga i te tono ki a koe tautapa i raro i taua tikanga o te kaiao:

• tonapuku;
• kanisā myelogenous;
• mate pukupuku, te whanaketanga o e pā te waha, pūkahukahu, repeure, kopirua ovaries (kia ngā therapy) ranei;
• osteomyelofibrosis;
• erythremia;
• te aroaro o te āhua mārere o te pukupuku i roto i te kaki, me te upoko, anake te okotahi ko te mate pukupuku e pānga te ngutu (reira he he hiahia mo te maimoatanga whānui);
• thrombocythemia faufaa;
• horionepitelioma kōpū;
• whakapeka rere kanisā lymphoblastic;
• thrombocytosis rite te pōauautanga o te syndrome myeloproliferative;
• mate o Hodgkin;
• takanga o te metastasis i mate pukupuku, te repe mammary ino, me te puku.

contraindications

He take i roto i te mea Kāore te maimoatanga tikanga "Hydrea". opani whakaritea i roto i ngā take pēnei i te ako rongoā:

• tūtohutanga High ki te capsules;
• thrombocytopenia me leukopenia i reiti o iti iho i te 100,000 me 2500 / ml aua;
• hapū, uma-kai waiu uma.

Ahakoa i roto i nga wā e whai ake nei me te tarukino kore e contraindicated, ka i whakaritea e ia, a titau i te tono tiaki motuhake:

• kūhuka-galactose malabsorption;
• reihuka;
• kore o te lactase;
• Taimaha rere anemia;
• tākihi kore me te ate.

Ki te mea kua mua i waiho i raro i te manawanui ki te hahau radiation therapy ranei, te mōrea o whakapeka erythema radiation me te whanaketanga o te myelosuppression, reira, i roto i tenei take, rawa, Me ki ata tono te rongoā.

I roto i therapy Me ārai pono, ki te otiia te hapūtanga, kia kia mōhio o te mōrea e te vai mo te kukune te manawanui. Nā ki te kătahi o te tarukino ki te waiu o nga wahine e whāngai ū uma, ko reira e tika ana ki te aukati i tenei momo o te kai. Ki te whakaritea te tarukino te ki te whakakore, kia tango i te mātanga ki pūkete te ngā ngā i mua i ka tukua reira te manawanui ki te paopao ki te maimoatanga e hāngai ana i runga i te fariiraa o capsules "Hydrea".

maimoatanga

I roto i te maimoatanga te medicament "Hydrea" ā-ako taunaki whakamahi pota rerekē o te kaihoko i roto i āhua rerekē, homai nga āhuatanga o te manawanui.

Ki te he uaua te manawanui ki horomia te capsule, he reira manakohia ki te whakatuwheratanga o te tarukino ki te memeha i te wai. I roto i ngā take pēnei, kia te kaihoko e inu tonu. kia whanau te reira i roto i te ngakau, e kore wāhanga katoa o nga capsules tareka ia i roto i te wai, e toe i runga i tona mata. Tūroro e te tukinotia "Hydrea", he mea e tika ana ki te inu nui o fluids.

kanisā Myelogenous (puka ma'i)

whakamana Treatment te kahore arumanga. Hoki nga manokaramu o taimaha tinana tangohia i runga i 20-30 mg o te tarukino. Tenei auau rā, pau te raau e kotahi katoa ra. kua whai wāhi ki te aromatawai i te whai huatanga o te therapy kua reira mō te 1.5 marama o tona whakatinanatanga. Ki te tuhia hua pai, ka taea e te maimoatanga e roa nui (i roto i te hiahia o reira), i hinga taumata o platelets me leukocytes raro mutu tona täkupu te. Ki te i muri i nga ra e toru (e kore i te aroaro o) hoki te toto ki noa, ka taea e koe anō therapy ki "Hydrea". Tohutohu mō te whakamahi whakaatu e hohoro ha faingamālie taua mai.

erythremia

Ko te horopeta hiahiatia hoki te whakahaere o ia rā o te 15-20 mg. Ka rite ki i roto i te take o mua, tatau tenei nui o te tarukino te ia manokaramu o taimaha tinana. Ko te ra Kei te nuinga whakahaere te manawanui 1 ranei 2 capsules. takoto horopeta Whakamutunga mō ia manawanui e tona taimaha, tei reira ki runga ki te nui o te tarukino i ai platelets me ngā taumata hematocrit he uara noa.

thrombocythemia faufaa

Ko te horopeta tuatahi ia manokaramu o taimaha tinana ōrite ki te 15 mg. whakaritea te horopeta rā te takitahi kia i ngā āhuatanga nui i te taumata tika. Ki te tirohia maimoatanga tarukino rāhuitia "Hydrea" taurite ako tākuta, me te kōwhiria e te tikanga tino tika ana.

tonapuku

Ki te taea e rānei taratahi tonu ranei pukupuku nui maimoatanga, aua, te horopeta tika o te medicament ia tetahi manokaramu o taimaha ko te 80 mg 20-30 ranei. I toru wiki, te roanga o te rongoā therapy tonu ia inu kotahi. Ki te kawea therapy te i roto i taratahitahi mo nga ra e toru, inu reira kotahi rawa, engari i te horopeta teitei.

Mate pukupuku (lesion waha, upoko kaki ranei)

Ko Per tinana manokaramu taimaha mo 80 mg o tarukino. pau te horopeta hiahiatia o rongoā te katoa ra e toru (kotahi).

pānga taha

A, no te raau therapy "Hydrea" ako, kua korerotia arotake etahi pānga taha ki te pūnaha hematopoietic, io, mimi, romahā me ngā pūnaha kūnatu. Hoki, kia kia pāngia te kiri, me te he taea ratou konga ki te whakawhanake i taua he mate, rite kikohangatia. Ka taea te tohua, me te tahi atu tauhohe kino.

Ko te utu o te raau taero, analogues

Hokona te mōkihi "Hydrea" taea e hoki 243-250 moni. (20 capsules). I roto i te whakakapi - teuteu e roto i te whakauru hohe taua rite te "Hydrea" me taero e whai he pānga rite.

O nga taurite taea e koe te hoko "hydroxyurea" ranei "Hydroxycarbamide Medak." A, no te opani maimoatanga "Hydrea" aratohu, e taea te tīpakohia analogs i te maha nui o medicaments, pērā i "Tromboreduktina" "FS amyl", "Kolotekana", "Milanfor", "Prospidin", "iritis", "halava", "Estratsita" "Irinotela", "Kamptotekana" ranei "Estratsita". Ka taea e koe te hoko whakakapi pērā i "Agrilin", "Kamptera" ranei "Erivedzh". I roto i te whakaurunga i reira he mahi ōrite "Aranoza", "Irinaks", "Arglabin". Rārangi ngā rongoā rite riro "Zaltrap", "Irnokam", "Geksalen". Ka taea te tukinotia te reira "Proksifeinom", "Gikamtinom", "Campto", "Verotekanom", "Hloditanom", "prospidin", "Onkofagom", "irinotecan" ranei "Velcade".

Reviews

He maha tūroro whakapono e te tikanga i mua i kia tīmata therapy kia tirotiro te whakaahuatanga "Hydrea" ako. Photos i mua i a taea hoki e te mataara e koe te pou-maimoatanga. Whakawa i te arotake, iwi hiahia ki te kia tukinotia anake i raro i te tirotiro hauora, me te kore mōrea ki te whaiaro medicate-, rite he kino tenei, inu nui o fluids. Ki te ngā kore tango rongoā e ki radiation therapy, pānga taha ranei puta (i roto i te wā i reira i mua ngaro), ranei riro noa atu korerotia. Otiia e kore e tupu tonu reira.