Ko te tono me te pānga o "Cefotaxime." "Cefotaxime": he orotahi o te tarukino

Rongoā paturopi "cefotaxime" - he tarukino kaha mo te maimoatanga o ngā mate hopuhopu, me te ārai o pōauautanga postoperative. Te raau whakaurua ki te tinana i roto i werohia, kua maha whakaritea reira mo e rua ngā pakeke me ngā tamariki. Ko te rongoā paturopi semisynthetic ki konutai te taonga kaha sefotaksim.

pānga pharmacological

"Cefotaxime" - cephalosporins māngai, whakarite mahi bactericidal e te pehanga o te hanganga o taiepa pūtau o huakita.

tikanga antimicrobial te mo te whakamahi parenteral, he reira whai hua, ka whai wāhi ki Gram-kino huakita e te hunga ātete ki ētahi atu paturopi, taea ki te mahi i runga i cocci karamu-pai, engari iti kaha i te huakita karamu-kino.

Pharmacokinetics

Kei te tere whenumi te tarukino, i runga i te inenga rānei kei roto i te wē o e rima meneti ranei te hawhe haora i muri i injecting me pupuritia e nohanga bactericidal i roto i te toto hoki neke atu i te 12 haora. Kei te tomo i te tarukino te kikokiko, me te inu, pai wehea i roto i a ratou. A, no te whakamahia i roto i te hohipera rongoā e taea te tiki ki te waiu uma. tutuki ana te mōrahi pānga "Cefotaxime" te ka nohanga whai hua i roto i te synovial, peritoneal me fluids pleural. whakamana te takenga te tonu i roto i te mimi (e pā ana ki 60%) me te i roto i te puka o metabolites. Hoki te hawhe-ora rite ki te hua o te V / m me te / i roto i te 1 hr hiahiatia.

Tuhinga hoki te whakamahi o te medicament

Tuhinga mō te whakamahi taero he natula hopuhopu o mumura whakapataritari e te moroiti e he feruriraa rerekē ki "cefotaxime" (te nuinga karamu-tōraro). Tukuna anake te tikanga mo te werohanga "Cefotaxime" analogs i roto i papa e wātea ana, whakamahia te raau taero i roto i te tautuhi i taua āhua:

• mate e pa ana i te kōhao puku;
• pāpaka o te kiri, hononga, kiko ngohengohe me te wheua;
• mate o te romahā api parau, ihu, korokoro, taringa;
• mate e pa ana i te pūnaha mimi;
• mate Lyme;
• inflammatory tukanga o hopuhopu āhua i te whekau papatoiake, gonorrhea;
• weranga, pangia patunga;
• meningitis, endocarditis, te septicaemia;
• mate o immunocompromised;
• ārai o te mate TB i muri i ngā tukanga hāparapara (ngā mahi i runga i nga whekau gastrointestinal wahi, obstetric me gynecological me ngā tukanga urological).

contraindications

"Cefotaxime" analogues i roto i te werohanga i etahi contraindications e Me whakaaro i mua ki te whakahaere o te tarukino.

contraindicated te raau i roto i te take o te hypersensitivity ki penicillins, carbapenems me ētahi atu cephalosporins. Ko tōna āta whakaritea mō te ate, me te tākihi mate, colitis ulcerative, hohipera. wahine hapu e whakaritea anake, ki te reira ko te tūpono nui ki te kukune te whaea o te tinana mahara ki te whai hua tino ranei tami te tūponotanga ka taea. A, no te whakamahia i roto i te pā ana ki ngā tamariki i raro i te tau o 2.5 tau, e kore whakaaetia ki te whakamahi i te tikanga o te werohia intramuscular.

Whakamahi o te raau taero, inenga

Ki te matau me pehea ki te whakawhānau "cefotaxime", he mea e tika ana ki te pānui i te kōrero i homai i roto i te tohutohu mo te whakamahi o te raau taero. Rongoā tikanga hoki te m / me / i roto i te whakataki (mā te dropper bolus ranei).

whakaritea te tarukino te hoki tūroro pakeke atu i te 12 nga tau, ka ko te taimaha tinana nui ake i 50 kirokaramu:

• mate hopuhopu o te mimi me te i roto i aua wā, ina puta te mate, kahore fifi kaiao e tetahi tikanga e wātea ana whakarato 1 go o te faaineineraa ki wā o 8-12 haora;
• ngāwari puka gonorrhea whakapeka whakahaere putawa i te intramuscular ara 1 go o tarukino;
• te whakamahi i te tarukino mo te maimoatanga o mate o te natura hopuhopu, he reo te pakeke o nei, e whakahaeretia ana i tetahi o nga ara ka taea o te 1-2g te ki te periodicity tikanga 12 haora (i mua i te tipu "Cefotaxime", he mea e tika ana ki te ako āta nga ture kia rite ki nei e rite te rongoā mō te werohanga) ;
• pakeke tupu mate, hei tauira, meningitis, e rapu te whakataki ki te rua 2 g o te tarukino i wā o 4-8 haora, ki te horopeta mōrahi ia ra kia kore neke atu i te 12 g; whakaritea roanga o te maimoatanga e te pakeke o te huru;
• i mua i ngā mahi i roto i rehunga ki te whakakore i te tūponotanga o te mate whakahaerea nei 1 go o te raau taero, i roto i ētahi wā kawea 6-12 haora te tikanga reintroduction;
• whakamana wāhanga cesarean e whakauru 1 go o "Cefotaxime" i muri toutou te tikanga te.

Kei te hoki whakamahia te raau e pâmuhia i roto i te pā ana ki ngā pēpi taimi halá, me hou:

• tau he iti iho i te 1 wiki - whakamahia 50 mg ia 1 kg o taimaha tinana ki te auautanga 12 haora;
• tau o te 1 ki te 4 wiki - 50 mg ia 1 kg o taimaha tinana ki te periodicity o 8 haora.

Tamariki e paunatia iti iho i te 50 manokaramu i te tau o 2.5 tau, whakarite 4-6 Whakataki tetahi o nga tikanga ka taea o 50-180 mg ia manokaramu o taimaha tinana (ki te kia matau rite "cefotaxime" momo novocaine, kia āta pānui i koe te tohutohu) . Ki te reira te mea he akoranga nui o te mate, te whakamahi o te 100-200 mg / kg. I ra e manakohia ki te 12 g o te tarukino.

Te whakarite o rongoā mō te werohanga

werohanga rō-uaua

Ko te horomata wai mo te werohia diluted (4 ml) i ki 1 g o te tarukino. whakahaerea ana te otinga te i runga i 3-5 meneti, he mea nui ki te whakarato i te tuku puhoi ki te tinana.

whaowhia rō-uaua (maturuturu)

I 50-100 mL o whakarewa (tēhuka 5% ranei konutai pūhaumāota 0.9% th) diluted 1-2 go o te tarukino me te kawea e whaowhia te i hoki 50-60 meneti.

intramuscular

I te 4 ml o otinga (1% -th otinga novocaine, te wai mo te werohanga) tango 1 go o te raau taero, hanga werohanga i te papa, me tomo te ngira hohonu ki te uaua.

Tautukunga ki tohutohu rongoā te whakamahi i

"Cefotaxime" analogues i roto i papa mo e reira e wātea ana, tono i roto i te hanganga ture ki te tohutohu motuhake. I mua i te tono i te rongoā e tika ana ki te aukati i te tūponotanga o mate pāwera. Tūroro ko wai e taea e te tauhohenga pāwera ki paturopi, kia whakamahia te tarukino ki te tūpato tino. Ki te kahore he tūtohutanga ki te matū i roto i roto i te hua rongoa, mutu tona whakamahinga te. I roto i te maimoatanga o neke atu i te 10 nga ra e titau te tirohanga wā o te tohanga toto piringa. Hei whakakore tauhohe houhou i roto i te maimoatanga Me ki te hoatu ki runga waipiro.

Overdosing pānga taha

"Cefotaxime" analogues i roto i te whakatārewatanga he maha nui o ngā pānga taha i:

• mate pāwera (urticaria, minamina, hikaka, kirika, Chills, bronchospasm, anafillaksiya, eosinophilia, angioedema, paitini necrolysis epidermal me Stevens-Johnson);
• dyspepsia (mamae i roto i te puku, dysbacteriosis, flatulence, whakapairuaki, ruaki, kōroke korere ranei, disorders o te ate, i roto i te wā onge - colitis pseudomembranous);
• glossitis, stomatitis;
• raruraru i roto i te pūnaha hematopoiesis (hypocoagulation, anemia hemolytic, thrombocytopenia, granulocytopenia, neutropenia, leukopenia);
• abnormalities i roto i nga whekau mimi (pauku interstitial, anuria, oliguria, azotemia, taumata tiketike o te Urea i roto i te toto);
• whanoke, ānini;
• tukanga kino i roto i te pūnaha Cardiovascular (arrhythmias mau ana i te riri pea ki te ora);
• tauhohe rohe houhou (urutomo, mamae / m, phlebitis);
• huringa i roto i ngā tawhā taiwhanga (teka pai Coombs 'whakamātautau);
• superinfection (candidiasis-waha, Candida vaginitis).

"Cefotaxime" orotahi o te tarukino, i te whakamahia i roto i pota tiketike taea arahi ki tuwhena rawa, aru e haehae me ētahi atu tohumate, i roto ia ratou - te manukanuka, tremors, encephalopathy (rawa maha kitea tenei tohu i roto i ngā tūroro mate ana i täkihi). Hei whakakore i whakamahia nga pānga o te maimoatanga symptomatic tuwhena rawa te.

pāhekoheko Drug ki ētahi atu rongoā

Ki te hiahia koe ki te kitea te tikanga ki te hanganga rite ki te hanganga o te moni e kore e "cefotaxime" orotahi huri kia uaua. Ko kahore mea, ki te meatia e te awhina o therapy tarukino te whakamahi i te orotahi taketake ranei, i roto i tetahi take, e hiahia ana koe ki te tango i ki pūkete te pāhekoheko o te tarukino me ētahi atu rongoa.

A, no te tano "cefotaxime" e rua ki taero pea nephrotoxic pērā i furosemide, paturopi aminoglycoside, he mea nui ki te mau te mahi o nga whatukuhu, no te mea o te mōrea o te pānga nephrotic.

Hoki te maimoatanga o maha mate, me te ārai i ō rātou whanaketanga maha whakamahi "cefotaxime". Tohutohu mō te whakamahi, kua ki te kia ako analogues tarukino, rite tenei taputapu e taea te meinga mate pāwera, kua he rota o ngā pānga taha, me te tahi atu āhuatanga. e kore ai te whakamahi i te rongoā o te tarukino roto i te taha ki te tahi atu rongoā o paturopi, e kore e taea te hono ratou ki te ruma te maturuturunga iho me te pūwero.

analogs

Tikanga hoki "cefotaxime" tairitenga me whiriwhiri hoki te taonga kaha. Ka taea te tāutuhia o analogues hanganga:

• cefotaxime konutai;
• cefotaxime oko, Sandoz, te konutai me te lek;
• tsefosin;
• tsefantral;
• tsefabol;
• tsetaks;
• tirotaks;
• tartsefoksim;
• taltsef;
• pupirikana-ki-tono;
• spirozin;
• rezibelakta;
• oritaksim;
• oritaks;
• liforan;
• klafotaksim;
• klaforan;
• klafobrin;
• kefoteks;
• intrataksim.

Mai i reira he he whānui o ngā taputapu mō te faaineineraa ngā "cefotaxime" tairitenga whiriwhiri ngāwari, engari t. Ki. Kia whai te analogs atu pānga taha, a kia waiho ratou pānga whakaora ngoikore, whakakapi kia te tarukino taketake rawa āta whiriwhiri. Hei karo hopearaa houhou, kia ako rite nui mōhiohio e pā ana ki taero e kua āta whakamaheretia ki te kia whakamahia.