Mate o Parkinson

mate a Parkinson (aka "Parkinson", reira "parkinsonism idiopathic", reira "parkinsonism tuatahi," aka "PD", reira "parkinsonism hypokinetic" me reira - "wiri pararutiki") - he arā o te io pokapū āhua degenerative o te pūnaha. tohu Motor e haere tahi i te mate Parkinson e pā ana ki te pūtau substantia nigra mate atu (i roto i te rohe waenganui o te roro) e hua dopamine. Aue, e kore e taea e te pūtaiao hou ano whakarato he whakahoki ki te pātai o te aha ohorere timata enei pūtau ki mate. I te timatanga o te akoranga tino kitea o te mate tohu kitea o te hunga e i roto i tetahi ara ranei tetahi, e pā ana ki te kaupapa.

Tohu o te mate o Parkinson ngā i roto i wiri ahau, rigidity me te whakaroa o te kaupapa, me te, rite te putanga, me te taahiraa kaupapa o te raruraru. I muri mai, me te whanaketanga o te mate, i reira kia kia he raruraru o-hinengaro, me te whanonga. I roto i te wāhanga i muri mai o te mate i roto i ngā tūroro kei te maha tohua e te tupu. Ētahi atu tohumate o te mate o Parkinson ngā raruraru ki te moe, kare me sensorics. mate a Parkinson he tino noa i roto i te paari, a ko te mate i roto i nuinga o te wā kitea i muri i te tau 50.

Tino maha tākuta ka hanga he tātaritanga "mate a Parkinson", Kei te ano honoa ki reira me te kupu "idiopathic", e ko, kotahi nei pū, e kore he take tonu ki te whakatū i taea. Heoi, i te rongoa mohiotia e rave rahi take o parkinsonism mohiotia i roto i nei ki te whakawhanake i te mate i te pānga tika, ko te āhua o te āhuatanga ira.

Ki te rā, kua tāutuhia kaipūtaiao he maha o ngā āhuatanga rite arai i te whanaketanga o te mate o Parkinson, ka whai wāhi ki tona whanaketanga. Na, mo te tauira, i kore i kitea e te mōrea o te whakawhanake i te mate i roto i kaipaipa ... i raro. Otiia maha mai te iwi ki te whakapā ki etahi patukīrea, i runga i te anga ke, kua tūponotanga teitei o te mate o Parkinson.

Pathologically āhuatanga te mate e haaputuraa o te pūmua i roto i te kopa o te tinana, e mohiotia ana ko Arepa-synuclein. Taua whakaeminga mohiotia rite "sino Lewy", e kitea e ratou i roto neurons o te nigra substantia. I tua atu, ka reira he iti whanaketanga o te mate me te dopamine mahi o Parkinson whakaputaina e te roro.

He tinana Lewy he ahua o te tapao o te parkinsonism idiopathic. Tau o ngā pūtau i roto i roto i te mamae roro i te mate o Parkinson, ko he taupū takitahi, engari e taea te whai pānga i te reira ki te pakeke, me te akoranga o te mate i roto i te takitahi. Tātaritanga o te mate o Parkinson te nuinga o hāngai i runga i nga tohu o te mate. E whakamahia ngā whakamātautau neuroimaging ki te whakaū i te tātaritanga.

tikanga o nāianei, kawea nei i roto i te maimoatanga o te mate o Parkinson, he ranea ki te akakoromaki tōtika ki faaiteraa wawe o mate e pā te kaupapa. Heoi, ki te whanaketanga o te mate ki muri te mate pūtau whakaputa dopamine, e hoko iti, me iti whai hua taua maimoatanga. I tua atu, whakatika te pōauautanga i roto i te mate o te manawanui, e mohiotia ana ko "dyskinesia", e faaite ake i roto i ngā nekehanga ka tuketuke te tumu. Heoi, kia rite ki hōia hua rangahau hauora, e taea te fakafiemālie'i'a tenei huru i roto i kai, me te etahi momo o mahi whakanohonoho. I roto i te tua, he tanga o tohumate kia whakamahi pokanga me te whakaongaonga roro hohonu. Kua whakamatauria enei tikanga whai hua, no te kore e tauturu i te whakamahi o ētahi atu raau taero me maimoatanga. Heoi, rangahau e hāngai ana ki te kimi tikanga hou, me te pono o te rongoā mate a Parkinson, tonu ki te kia kawea i roto i.