Nasal rehu "Dezrinit": arotake o tākuta, tohutohu hoki te whakamahi me te hanganga

"Dezrinit" - glucocorticosteroid waihanga (GCS) tono wā. Ko te kaihoko kaha he mometasone mahi antiallergic me antiinflammatory. I roto i te faaohiparaa i te raau taero i roto i pota e kore meinga e pānga pūnahanaha faaite mai ona anti-inflammatory mahi wā. Whakaaroa tenei tuhinga e pā ana ki "Dezrinit" whakautu faaineineraa i rata me kiritaki.

aukati te tarukino te tuku o kaitakawaenga inflammatory, nui haere lipomodulin production, ko te inhibitor o phospholipase A, ka he tika ki te whakaiti o te arachidonic waikawa me te prostaglandin kōtuitanga inhibition tukua me endoperoxides huringa tenei. Ko te tarukino, ko te ki te ārai i whakaeminga o neutrophils, whakaiti i te hanga o te exudate inflammatory me lymphokine, inhibition o hekenga macrophage, whakaiti tukanga granulation me kookuhutanga, te whakaiti i te hanganga o te chemotaxis, arā pānga i runga i te tauhohenga i muri pāwera puta mutu te whanaketanga o te tauhohenga pāwera tonu.

whakapumautia ana tēnei i runga i te medicament "Dezrinit 'arotake o tākuta - tohunga i roto i to ratou mara. Ko te tikanga hanganga ngā mometasone furoate me pŭpŭ tauturu.

Pharmacokinetics

tono Intranasal whakaiti bioavailability pūnahanaha o te mometasone furoate ki iti iho i te 1%. taonga Hohe taea ki te tiki i ki te toto, i roto i ngā rahinga iti whenumi me mātātoa biotransformed i muri i te haere tuatahi i roto i te ate. I runga i te faaineineraa e te nuinga pai "Dezrinit" Doctors arotake.

Kei te tohua hoki:

• te maimoatanga o te koiora me te kaupeka Rhinitis tamariki mate pāwera i te 2 nga tau, me te pakeke, me ngā pakeke;
• pakohu kakā whakapeka, exacerbation o ma rua nga tau o tau me te pakeke, me ngā pakeke (tae atu i te feia ruhiruhia) rite te maimoatanga adjuvant ki paturopi pakohu kakā tamariki ma'i;
• maimoatanga o adenoids i roto i ngā tamariki pakeke polyposis nasal ranei;
• ārai o te Rhinitis pāwera tau i roto i ngā āhuatanga āhua, me te nui o ngā tamariki i ma rua nga tau o te tau, me te pakeke me te pakeke. tūtohu Whanonga mō te wha wiki i mua i te tīmatanga o te dusting wa.

Puka tuku

rehu nasal Metered. kei Kotahi oko 140 werohanga. Ko te puka tohutoro o te raau taero i roto i te puka o rūrūtia kore te tīariari i roto i te wa o te faaineineraa tānga. E tika ana "Dezrinit" tamariki. Reviews o tākuta whakaū i te reira.

Ko te tikanga o te whakamahi me te tohutohu mo te whakamahi

whakahaere te tarukino te intranasally. Kei te patia rehu roto i roto i te oko ki te ihu te whakamahi i te pūrere dosing motuhake.

I mua i te tīmatanga o te tono o te rehu ki te mahi 10 körere whakamātautau i runga i te pūrere dosing. I muri i whakatika, whakaturia te auau tuku rongoā te, pīrori whakatārewatanga o 100 mg i roto 50 mcg o te mometasone ia press. I mua i te whakamahi i te hua i muri i neke atu i te mea kiano i matao 14-ra, me kia korerotia te whakatika. Me haere tahi ia tono i te tuatahi i wiri te oko.

pānga taha

Mō "Dezrinit» Teuteu arotake hauora whakaaro nga pānga taha taea e whai ake nei:

• papahewa;
• tauhohe hypersensitivity tae atu dyspnea, me bronchospasm;
• anaphylaxis;
• ānini i roto i ngā tamariki me ngā pakeke;
• angioedema;
• nosebleeds;
• mura o te kōhao nasal;
• kia wheako tamariki tupu nga akaaka, whakamātau tinana te totoa, disorders moe, manukanuka, whanonga kaitaua, korekore;
• nui korokoro;
• perforation o te pakitara wehewehe nasal ;
• mana'o o ritenga o nga mucous i roto i te kōhao nasal;
• sensation ritenga mucosa pharyngeal;
• runga mate wahi romahā;
• tihe;
• te reka o te pororaru o;
• takahi o te tikanga o te kakara;
• awhiowhio wai;
• nui haere te pēhanga intraocular;
• ulceration o te mucosa i roto i te kōhao nasal.

contraindications

contraindicated Drug "Dezrinit" (arotake o tākuta whakau reira) te roto:

• hypersensitivity ki mometasone tetahi wae o te waihanga ranei;
• .. ki te wawaotanga hāparapara tata nasal ngaukino ranei maru ia whakaora, e mahi ki te tikanga inhibitory GCS i te whakaora tukanga;
• i roto i te tamariki (ki te polyposis nasal 18; exacerbations whakapeka o pakohu kakā ma'i, whakapeka ake ki 12 tau ranei; koroheke 2 Rhinitis ki pāwera te koiora, me te tau).

Ko te whakamahi o te raau taero i roto i te hapū, me te ū

Rawa i whakahaeretia kahore rangahau o te whakamahi haumaru "Dezrinita" i roto i te hapū, me te hohipera. kia tenei tarukino kia whakahaerea ki te whāngai ū me te wahine hapu anake, ki te nui hua hauora o te whaea i te mōrearea ki te tamaiti kukune ranei. Hou nei metua vahine whakamahia corticosteroids i roto i hapūtanga, e hiahia ana koe ki te haere i te whakamātautau motuhake ki te tāutu i taea hypoadrenalism. whakapumautia ana tēnei i runga i te medicament "Dezrinit" arotake o immunology hauora.

Whakamahi o te tarukino mō ngā tamariki

contraindicated te whakamahi o "Dezrinita" Kei roto i ngā tamariki ki te nasal polyposis kōhao 18; he exacerbation o pakohu kakā ma'i puka whakapeka o runga ki te 12 nga tau ranei; ki te koiora me te kaupeka Rhinitis pāwera ki te 2 tau. whakamahia pinepine "Dezrinit" i roto i adenoids i roto i ngā tamariki. He pai Reviews o tākuta faatura tenei i roto i.

tohutohu mō te whakamahi

Tohu o atrophy o te mucosa nasal i muri i maimoatanga mō te kotahi tau (12 marama) kihai i kitea. He ako o biopsies o mucosa nasal whakakitea te pānga o mometasone ki te ia o te māori o histology. whakamahi wā roa o te raau taero, me te tetahi maimoatanga wā roa-, tā inspections wā nasal otorhinolaryngology mucosa rata.

I roto i te mate kohi airway (moe kaha ranei); (Pānga tae atu herpes nga kanohi, ranei Herpes māmā) kitakita, nahanaha viral ranei mate fungal; maimoatanga auroa e corticosteroids; te aroaro o kāore mate paetata o te mucosa nasal, me te whāngai ū me te hapū, kia whakahau i te tarukino ki te tūpato.

tikanga Treatment "Dezrinit" tūtohu ki te mutu, ka timata ki te whakahaere therapy motuhake i roto i te whanaketanga o te mate fungal rohe o te pharynx ihu ranei.

Ritenga o te pharynx me nasal kōhao, e tonu hoki o te wā, he wā tino roa, ka taea te whakaaro he tohu mo te kore o te tarukino. Ka taea hoki te mōhio e kore i whakakitea ai pehanga o te pūnaha hypothalamic-rapae o-adrenal whakamahi i muri roa o te tarukino. Ka kitea tënei e arotake o te faaineineraa "Dezrinit".

tokanga makehe ki ano e rapu tūroro fariiraa i maimoatanga roa ki corticosteroids, haere ki te maimoatanga ki mometasone. Ki te whakakore koe te mahi pūnaha GCS, ka he tupono taea tatou te mea e ka meinga e te reira i te kore o te mahi adrenal, te maimoatanga o e ka rapua e mehua e tika ana.

I roto i te tahi mau tūroro, te whakawhiti ki te maimoatanga mometasone i muri corticosteroids kia puta tohumate withdrawal whakamahi pūnahanaha o glucocorticosteroids. Ko ētahi o ēnei korekore, rohirohi, te mamae i roto i te uaua hononga, me te / ranei. Me tūroro motuhake riria e maimoatanga ki "Dezrinit" he tika, ahakoa te whakaiti i roto i te pakeke o ngā tohu o pāpaka mucosa nasal. Tapo'ihia (engari kua vai i roto i te manawanui) maimoatanga o glucocorticoid mate pāwera nahanaha pērā i katoatia me pīkaru, e taea te tāutuhia ki te whakawhiti ki corticosteroids rohe.

I roto i te maimoatanga o polyps unilateral; kore i polyps, e kua pā ana ki Simi, me polyps, tino uhi i te kōhao nasal, te haumaru me te aonga o "Dezrinita" Kua ako. Toto me polyps unilateral he he āhua kōhikohiko, he mea e tika ana ki te tirotiro anō.

Tūroro te fariiraa therapy i corticosteroids, te tiki i te tauhohenga ārai iti a reira whakatupato kia ratou ki te whakapiki ake i te mōrea o te mate i roto i whakapā ki karawaka mate, koroputa me etahi atu āhua hopuhopu o te mate, me te hiahia ki te kōrero i te tohunga, ki te te whakapā ki te manawanui tonu ka tango ahau wahi.

whakamahi auroa o corticosteroids nasal i roto i pota nui e taea e te whakakōkī mo te whanaketanga o ngā pānga taha. Heoi, ka taea e enei pānga kia matara iti pea atu ina e whakamahia corticosteroids pūnahanaha, me rerekē i roto i te tūroro takitahi. kia ngā Pümanawa pānga pūnahanaha syndrome o Cushing, āhuatanga nei i te pehanga adrenal, papahewa, awhiowhio wai, te retardation tupu i roto i ngā tamariki me ngā taiohi, me ētahi wā he maha o ngā pānga whanonga, me te hinengaro, tae atu manukanuka, ngangau moe, korekore ranei fakaaoao, whakamātau tinana te totoa.

Ko te ngā tarukino i waenganui i rerekē taero ki mometasone, i whakahaere e pā ana ki tenei rangahau.

Nasal rehu «Teva Dezrinit": arotake kiritaki me kaiwhakaako

Reviews o te faaineineraa te nuinga pai. tokoni pai ki Rhinitis pāwera. Tikanga nohotahi uaua hoatu pānga taha. Young tamariki tauturu i roto i adenoids, te whakaiti mumura. Ko te mea matua ki te faatura i te tohutohu mō te whakamahi.