Pemphigus vulgaris: take, tohu, maimoatanga, rongoā. mate autoimmune

Nahea te mate taua, pērā i pemphigus? E kōrerohia Treatment me tohu o tenei mate i raro. Ka ako ano hoki koe e pā ana ki te take o tenei tukanga mate me pehea tona tātaritanga.

ngā mōhiohio taketake

Pemphigus, photo aroaro nei i roto i tenei tuhinga, - he rōpū o onge engari tino nui, haaparuparu me pea mate mate autoimmune vesiculobullous e pā te kiri me kiriuhi mucous.

Tohunga tautuhi nga momo e whai ake nei o te mate:

• pemphigus vulgaris;
• vegetans ahua;
• te rau;
• seborrhoeic (kia whai ingoa pērā i Heniri-Usher syndrome, erythematous ranei).

āhuatanga General o te mate

vulgaris Pemphigus tohu te kāwai o mate o te kiri, me te kiko subcutaneous, e rere i roto i te puka ma'i, ki relapses auau.

Tenei mate, ko te ira ti'aturi. Kei te āhuatanga i te reira na roto i te akoranga ahu whakamua, me te te hanganga o opupu intraepidermal.

Nuinga o ngā wā, ka pā pemphigus vulgaris iwi 50 tau, neke atu rānei te pakeke.

He aha te puta tenei mate? Ko te take mo te whanaketanga o tenei mate, i reira he whakapae anake.

Pemphigus: te take tino pea

I mua i te maimoatanga, ko te tino nui te mate i roto i te pātai ki te kitea i roto i te aha te mea ka whakatika te mate autoimmune i te manawanui ngā. Kia aroha mai, i kitea i te take o te pemphigus he uaua. Kei te aro tohunga ki tenei raruraru mō ngā tekau tau maha. I roto i tenei wa kua hoatu e ratou i mua he whakapae:

• āhuatanga exogenous, arā tango rongoā, tae atu rongoā paturopi me ona pärönaki, me ngā interferons me ētahi atu mea.
• āhuatanga Endogenous, tae atu ārai me te ira.
• āhuatanga ā-(kia pā riro weranga whānui, me te radiation).
• Endocrine (kore hei tauira hormonal i roto i te tangata).
• Wheori (Herpesviruses).
• Tango etahi kai.

I runga i enei āhuatanga, whakamārama i te takanga pea o te mate, faaoti tatou: taea vulgaris pemphigus e immunological, endocrine, hopuhopu, neurogenic, paitini, me ētahi atu Heoi, kia tuhia te reira e reira he tonu unknown ranei he tuatahi taua huringa ranei kakahuria e ratou .. āhua Tuarua, i roto i te whakautu ki te take pakiaka.

Ko te kupu, ko te ngoikore ki te tautuhi i te take tangohia o te whakaaro mate autoimmune tino āhuatanga tona tātaritanga wā, kia maha whakawhanake maha iwi pōauautanga nui.

tikanga nucleation

Kia pehea te ko te whanaketanga o taua mate, pērā i pemphigus? Whakaahua wāhanga tuatahi o te mate, ka taea e kite koe i roto i tenei tuhinga. Tohunga mea e te take o taua tukanga autoaggressive pathologic ko te hanganga o paturopi ki pūmua no ki te hapu o te desmoglein. Ko te whakamutunga tohu te ahua o "kāpia" e hono pūtau epidermal pātata mā huānga honotanga motuhake, e te hunga kua huaina desmosomes.

lymphocytes Kia whakahohe me autoantibodies te whawhai ki nga desmogleins, kua wehea ngā pūtau epidermal i ia atu, a ka riro maiengi te kiriwaho me te "whakapiri", reira ngāwari tihorea atu, ka waiho i raro ki te kătahi o ngā harore me huakita. I roto i te mahi haumanu, i huaina tēnei āhuatanga ko acantholysis.

Ka rite ki te hua o te tukanga i runga ake i te manawanui he opupu i runga i te kiri, me te tona matotoru. I te wa ano e ki tonu ratou i te exudate me kua pirau tonu. Neke atu i te wa, kua tihorea atu nga mirumiru i te pepa, e tuu i te kikokiko, me te hanga pirau, me mariao huaketo. I roto i te wā matatau, kia hipokina taua hanganga nuinga te mata katoa o te tinana.

mōhiohio hītori

Tuatahi he tohunga mate Dermatological kahore e mohio tata tetahi mea. Ko te wā "pemphigus" tono ki pāpaka katoa o mucous me kiri, acantholysis haere tahi, hanganga o mirumiru me wehe o nga pepa ki te whanaketanga o suppurating tuwhenua. Heoi, i roto i te 1964 whakaputaina he tuhinga i roto i te buka aamu hauora, i puta ke te māramatanga o nga kaiwhakaako i runga i te mate i roto i te pātai, me te tona huarahi ki te tātaritanga me te maimoatanga. Mai taua wa, i te aroaro o paturopi i roto i te wē toto o tūroro ki desmogleina riro te paearu matua mō te tāutu o pemphigus.

E te ara, i roto i 1971 whakaputaina e ia tetahi atu tuhinga i roto i nei te āhua autoimmune o te uiui, i roto i te taipitopito me te huarahi o te whanaketanga o tenei mate.

Ko te tohu matua

Opupu i runga i te kiri, hua i te whanaketanga o te bladderwort faufau noa ranei, tohu te tohu tuatahi o te mate. Me kï reira e puta tenei momo o te mate tino maha. E ai ki te tohunga, pūkete reira hoki 77% o ngā momo kitea katoa o pemphigus.

Pāpaka i roto i te puka o mirumiru pānga te kiri e kore e anake o te manawanui, engari ano hoki te mucosa o te mangai, me tona korokoro. I muri horahia e ratou i roto i runga i te alangá, kikokiko waho, mata, me te pera i runga i.

He aha kia mohio koutou e pā ana ki enei mate kiri? Tikanga, whakawhanake ohorere pemphigus. Ko te kupu i runga i te kiri hauora waho i hanga raruraru mirumiru iti e ki te tere taonga ahua momohe appreciable. He mārama serous wai (paku mangu) o ratou hei tirotiro.

I muri te whakatuwhera i te papules i hanga mata horo, e muri whakaora, engari waiho tohu o ähua o parauri.

Hoki te taua mate autoimmune āhuatanga e kino rere ma'i i roto i te puka. Me kï te reira i taua i roto i te tahi mau taata, kahore kitea tetahi maimoatanga i whakapai ake noa, i whakakapi i te whakahōhā.

mate Tino maha haere tahi pemphigus vulgaris Tuarua (candidiasis).

Nā ki te mate pūmua, fluids me ngā pānga hopuhopu waitohunga o tenei mate ki te puka nui kino.

Tāutunga o mate

Ka rite ki whakakitea vulgaris pemphigus? kawea tātaritanga o te mate i roto i roto i te fare ma'i. kitea te aroaro o te mate e hāngai ana i runga i ngā tohu haumanu me te hua o tätari.

ngā te mua:

• He tohu o te papa kiripaka-Hansen. kitea ana tēnei āhuatanga e mā te pēhi i te ringa i runga i te uhi karaihe (i.e., e kore ano ngoto) mirumiru ranei. Taua tikanga whakahaere wehe o te kiriwaho i te wāhi i te mea pātata ki papules, me te whakanui ake i tona rohe e tika ana ki te pēhanga inu i roto i te kōwae.
• Tohumate Nikolsky. kitea ana tēnei āhuatanga i roto i mongamonga mirumiru entrainment ki Kuku, me te mea komukumuku he wahi maihao waho kiri tonu e tata ana te pae lesion. Ko te kupu i reira ko te wehe o te kiriwaho.

Me kï reira e te pemphigus ino e kore e motuhake enei tohu, me tātaritanga. Kia mahara te reira e kia puta i taua mau faaiteraa i roto i te tahi atu mate.

whakamātautau taiwhanga

Kia pehea te pāngia te vulgaris pemphigus? kia kawea maimoatanga o te mate autoimmune i muri noa i te whakamātautau hauora. Ki te kitea taua whakamahia he mate te:

• tātari Histological, whai wāhi whakamātautau o waimeha, te pera-ka karanga tapumati ranei ki te tāutu i te pihaa pūtau acantholytic (arā, ngā pūtau epidermal e kua oti huringa morphological).

Me kï reira e runga i te pūtake o te tātari histological o raraunga ki te faaoti e te whanaketanga o te mate autoimmune e taea. Ko e tika ana ki te meka i reira e te tahi atu mate ki te pikitia rite tenei.

• tikanga Immunofluorescence ki te kitea putunga intracellular o immunoglobulin G ko A, me te ki te tautuhi matua me te iti antigens - desmoglein 3 me desmoglein-1. Tenei tikanga ko te tātaritanga tika tino.

Ko te kupu, whakanohoia te tātaritanga "pemphigus ino 'e hāngai ana i runga i ngā raraunga tāpiripiri o ngā tohu haumanu me te pikitia haumanu o te mate, me nga hua o te immunofluorescence tūāhua me te whakamātautau histologic.

maimoatanga

I te timatanga o te whanaketanga o te pemphigus vulgaris tūroro whakaritea glucocorticoids. Drugs i roto i tenei rōpū riro i roto i pota ru. Ko te whakarite o te raau taero i roto i ngā rahinga nui o taunakitanga faufaa. Ki te whakaaro ki te contraindications me ngā pānga taha, he tuarua ratou.

He aha te ki te mate i roto i te pātai whakahau glucocorticoids? kia Teuteu mo te maimoatanga o te puzyrchaki mangere e whai ake: "Prednisolone" "Dexamethasone" me "Triamptsinolon".

Kia whakapai ake o te manawanui, i.e. i te ngaro o mirumiru hou, heke te horopeta o taero te āta, me te neke i te tautoko i roto i te tikanga ki te ārai i hohokitanga. Taua maimoatanga o tūroro roa nui.

Haunga glucocorticoids, kia tautapa tūroro āpiha cytotoxic, immunosuppressants, tae atu "Methotrexate", "Azathioprine" ranei "Prospidin". E tika ana ki te tango i nga raruraru o tauhohe kino i muri i ingestion o taero taketake ratou.

Ētahi atu tikanga maimoatanga

Ki te mea i reira he tohu e i roto i tūroro mate autoimmune taea te tukinotia ki paturopi, me taero e tautoko i te pūnaha Cardiovascular, whakahaere pēhanga toto, me te haerenga i te mahi o te ate, me nga whatukuhu.

hiahiatia hoki te horomanga o pāhare pāporo-kei roto āpiha, te konupūmā me te huaora. Ka taea te whakamahi hoki i te maimoatanga wā o taero anti-inflammatory pemphigus, infusions me decoctions o otaota.

Me mahara hoki käore te reira i taua, i runga i te huru o te manawanui kia faataahia te reira ki taua ngā tukanga rite gemabsorbtsiya, huhu o te toto, me te plasmapheresis rānei.