Prednisolone: tohutohu mō te whakamahi, te āhuatanga pharmacological

Tuku puka "Prednisolone" raau: ngohengohe momo rongoa - hinu.

Farmsvoystva

Prednisolone Ko te orotahi dehydrogenated o hydrocortisone. Antiallergic, antiinflammatory, pānga antiexudative me antipruritic ka whakamahia fakahokohoko fakakaveinga hinu "prednisolone" ako ai he hekenga i roto i te hanganga, tuku me te mahi o kaitakawaenga mumura (kinin, he histamine, whākōkī lysosomal, prostaglandins). Hoki aukati hekenga pūtau ki putake inflammatory heke vasodilation me nui haere uruhanga iaia e puta i roto i te mumura. Whakaiti i te exudation he tika ki te mahi vasoconstrictor o "Prednisolone" tarukino. Manual tohu e te tarukino ko te pānga immunosuppressive mā te hëoi te mahi o te matatini antigen-antibody, me te piki i runga i nga taiepa o oko toto, me te ko te take o te vasculitis mate pāwera. inhibits te tarukino te mahi o macrophages, cytokines, pūtau ūnga e meinga te whanaketanga o te momo tauhohenga pāwera dermatitis ma'i pee. Ko te kupu e kore e taea sensitized T-lymphocytes me macrophages whiwhi wāhi ki te pūtau ūnga.

Pharmacokinetics

A, no te riro te tono o te hinu "Prednisolone" me te taonga kaha kei roto i te bloodstream. I roto i te wē prednisolone toto he hāngai ana ki te albumin me transcortin nui wahi. Biotransformation prednisolone puta i hāora, te nuinga i roto i te ate, te wahi glucuronidation sulfation ranei puta puka oxidized. I roto i te puka o metabolites excreted i roto i te mimi me feces, he wahi - i roto i te āhua, nā. haere Prednisolone roto te arai placental i roto i ngä nohanga iti, e taea te kitea i te reira i roto i te waiu o te wahine uma.

Prednisolone: iteraa papû

whakamahia te raau i roto i te wā o:

- dermatitis whakapā pāwera, me te tumu,

- katoatia,

- atopic dermatitis,

- dermatitis seborrheic,

- psoriasis.

Prednisolone: ako

Kei te tono te hinu ki te pae marutanga whakanoho 1-3 wā / ra. meinga roanga o te maimoatanga e te āhua o te mate, me te nuinga o te wā pumau mo 8-14 ra. kia hinu i roto i te maimoatanga o tamariki roanga o te maimoatanga kia heke ki te 3-7 ra, mai te mea atu tairongo ki te tarukino "Prednisolone" te tinana o te tamaiti. E taunaki ana te ako whakarerea warming, whakatika me dressings occlusive.

Āhuatanga o te tono

Ko te roanga o te maimoatanga ki te hinu kore e waiho atu atu i 14 ra i roto i te tikanga ki te ārai i ngā pānga taha taea i te whakamahi o "Prednisolone" tarukino. whakatakoto ako ki te hamani anake i raro i te tirotiro hauora.

pānga taha

Ko te tikanga kei te pai te nohotahi te tarukino. Varavara, rawa i muri i te whakamahi roa, kia meinga minamina, tahu sensation, erythema. I roto i te tahi mau tūroro kia faaite mai i te pānga taha rite folliculitis, hypertrichosis, dermatitis perioral, tauhohe mate pāwera ki wāhanga rongoā. E kore e nga tohu i runga rapua e maimoatanga, me te hohoro nekehia atu i te whakamutunga o te tono o te tarukino. Kia mahara te reira e kia puta te tono o te hinu ki te kiri i pangia, me te whakamahi wā roa-(rawa i roto i te mate o ngā wāhi nui o te kiri) ngā pānga taha o te āhua pūnahanaha.

Taunekeneke ki ētahi atu taero

Prednisolone kua te taonga ki te whakatairanga pānga anticoagulant o anticoagulants. faarahi te reira i te taea o toto i tango salicylates. faarahi te reira i te tūponotanga o disorders kawehiko pākia ki whakahaere te rere o Diuretics. He he he tipu mōrearea o te tāoke ka whakamahi i glycosides cardiac. Heke pānga antidiabetic hypoglycemic me te heke te mahi antibacterial o rifampicin. Ehara i tūtohutia hoki te whakamahi i roto i te taha ki te waikawa.

contraindications

rāhuitia Treatment "Prednisolone" ako hinu i roto i:

- hypersensitivity;

- kitakita, viral, pāpaka kiri fungal;

- kohi, paipai pākewakewa, pukupuku kiri, hapūtanga, hakihaki noa me te hakihaki māwhero.

tuwhena rawa

E unknown Kēhi o tuwhena rawa.

tikanga rokiroki

Puritia i runga i te rārangi B, i 5-15ºS. ora papa - 2 tau. I te paunga o te ora papa kore ki te whakamahi i.

tikanga o te supply

Whakahaunga.