Drugs "Metodzhekt" me "Methotrexate" - he aha te te rerekētanga?

I roto i tenei tuhinga whakaaro tatou i te mau faaineineraa "Metodzhekt" me "Methotrexate". He aha te mea te rerekētanga i waenganui i a ratou? I runga i tenei i muri mai.

"Metodzhekt" ko he kaihoko anticancer, e kua he pānga immunosuppressive tohua, ko reira he enemi waikawa folic. Ka taea e mutu te whāū pūtau. mahi hoki tōna mahi matua rite inhibition o reductase dihydrofolate, he pūmua whākōkī matua o te waikawa tetrahydrofolic dihydrofolate whakaiti. Ko te utu o te tarukino - i 700 ki te 1100 moni.

Ko te tino rongonui orotahi "Metodzhekt" takanga ko te Austria "Methotrexate Ebewe".

tona utu Ko te reira i roto i te whānuitanga o i 400 ki te 1200 moni.

Composition "Metodzhekta"

Ko te whakauru matua kaha o te tarukino he methotrexate disodium. wāhanga atu: pūhaumāota konutai, konutai waihā, te wai māturu.

Ko reira whai hua ki te faatura ki te tupuranga me ngā pūtau tipu. Rawa pā reira ki epithelial pūtau me neoplasms mārere.

I tono tamau piki i roto i te kopa. Excreted e nga whatukuhu, me te ate. Ki te taupatupatu koe tākihi mahi, excretion i te tinana pōturi iho. kia hoki pōturi te reira i raro me mahi ate rawakore.

Ko te hanganga o "Methotrexate Ebewe"

Hei wāhanga o te tarukino ko te whakauru hohe taua - methotrexate. He āhuatanga immunosuppressive, anti-puku.

He bioavailability pai excreted i roto i te mimi me te iti o te ate. whangai ana te reira ki te whakaemi i te kopa i roto i te puka o metabolites.

Na, "Metodzhekt" me "Methotrexate" - he aha te te rerekētanga? E ai ki te hanganga me te mahi e whakaritea ōrite.

I roto i ētahi wā, te faataahia "Metodzhekt"?

Drug "Metodzhekt 'i roto i te matepukupuku te uaua whakamahia. Kei te tohua te reira no te mate kiri me mate o nga hononga, pērā i:

• Psoriasis, i te mea uaua ki te hamani.
• kaikōiwi.
• rumati punua.
• rumati Psoriatic.

immunosuppressive nā me ngā āhuatanga anti-inflammatory o rongoā. E whakamārama ana tēnei i te whai huatanga i roto i enei aorangia hoki.

Ko te whakamahi o "Methotrexate" tarukino

Fele, "Methotrexate" tohua mo te maimoatanga o te mate pukupuku:

• kanisā lymphocytic whakapeka;
• mate trophoblastic;
• mate pukupuku kiri;
• pukupuku i te waha, me te teke;
• mate pukupuku o te pū kai;
• mate pukupuku pūtau squamous o te matenga, me te kaki;
• mate pukupuku o te papatoiake tākihi me te awa mimi;
• me sarcomas osteogenic myagkokletochnoy;
• sarcoma o Ewing, pūkahukahu mate pukupuku, mate pukupuku uma;
• te pukupuku iroriki pūtau o te raho me te kura kākano;
• mate pukupuku ate, tākihi pukupuku;
• retinoblastoma, medulloblastoma;
• mate pukupuku penile;
• mate o Hodgkin.

I tua atu, kia tuhia te reira e tono te medicament te me i ngā āhuatanga nui o te psoriasis rite te pai kia rite ki i roto i te take o te nui kaikōiwi (ki te i whai hua e tika therapy).

Ko te te rerekētanga. "Metodzhekt" me "Methotrexate" e whakamahia mō te rerekē mate. Ko te kupu, "Metodzhekt" - mo te maimoatanga o te psoriasis me te rumati, rite "MTX" - i roto i te matepukupuku. Ko taea te tukinotia ratou a ka, me te ake.

issuance

"Metodzhekt" - he otinga mārama kōwhai. Hokona tahi me pāhorehore, e kua tikanga ki te kia whakahaerea i raro i te kiri, ki te uaua rua ranei.

"Methotrexate" kei roto i ampoules me papa.

Ka rite ki taero whakamahia?

Ko te inenga o te raau taero tīpakohia e te rata haere i runga i te pūtake takitahi. O te akoranga, ki te reira he kahore contraindications. Kei te whakamahia te reira i kore ake atu i te kotahi i te wiki.

Me tango te manawanui te whakamātautau i mua i te whakamahi. I roto i te mua, i roto i pā ana ki te wiki, kia he whakamātautau hukihuki ki iti o te raau taero, ki te tauhohe tikanga te tinana, e taea te kawea te maimoatanga i roto i.

Ko kore hāngai, no te pānga taha faaineineraa. Tuatahi, kua whakaurua te horopeta iti o medicament, e ko te 7.5 mg. Na āta reira nui haere, ki te tolerability pai me tohu ngā.

I muri o nga marama i te rua, i muri i te tono tuatahi, ka kite koe i te pānga. Ko te akoranga ka taea e muri mo te wa roa, ki runga ki te maha nga tau.

Te whakamahi i roto i nga wahine hapu me te lactating

Tenei te te rerekētanga? "Metodzhekt" me "Methotrexate" e kore e tika kia tangohia i roto i te hapū, me te hohipera.

"Metodzhekt" he paitini ki te kukune kia arahi ki raruraru nui i roto i te whanaketanga, me te tae noa ki tona matenga. I roto i te uma whangai waiu ki te whakaemi, e taea hoki e pēhia ngā hauora o te tamaiti.

Ki te te hapūtanga i roto i te maimoatanga, i reira kia kia hopearaa houhou mo te tamaiti. Na reira Me ārai tupato i roto i therapy.

whakarite tatou i te "Metodzhekt" raau taero, me "Methotrexate Ebewe". He aha te mea te rerekētanga, ko reira mahinongofua. E uiui atu.

"Metodzhekta" Contraindications

e kore e whakamahi i te rongoā, ki te reira ko te hypersensitivity ki te wae. E kore kia whakamahia reira ka:

• Abuse waipiro.
• Ate me whatukuhu.
• Hemodyscrasia.
• Aroaro o keha i roto i te wahi kūnatu me i te kōhao-waha.
• Vaccination (e tika ana ki te whakaiti o te whakautu ārai, kia kawea werohanga i fariiraa e ono anake nga marama i muri i mutu).
• mate whakapeka, me te ma'i (tae atu ki ngā mate tata).
• mate Autoimmune.

kia tono tupato ki te reira ko te:

• Herpes.
• Pleural me effusions peritoneal.
• Ascites.
• Kauti.
• mate taunutia o te pūnaha kūnatu.
• Maroketanga (toenga wai ohorere tikanga piki tāoke).
• Asthenia.
• He kukū nui o bilirubin.
• Te Ruaki me te korere.
• Whakahaere matū me te radiation therapy hītori.

"Metodzhekt" tamata kore ki te whakarite i te ruhiruhia no te mea kia kua raru ratou i te ate, me nga whatukuhu. I roto i te ngā, e kore e whakamahi i "Metodzhekt" me "MTX" i roto i UC (colitis ulcerative).

I roto i ētahi wā, kua riria ai ki te whakamahi i te rongoā, "Methotrexate"?

A, no te whakahuatia ate tangata, me te / ranei tākihi mate, leukopenia, thrombocytopenia, hapū me te hohipera. Kei te contraindicated hoki āhua ārai mō te whakamahi "methotrexate".

A, no te hamani rongoa kaikōiwi psoriasis ranei, kotahi te marama, ki te hoatu mataora toto, rite i roto i ngā āhuatanga taiwhanga ko reira e tika ana ki te tirohia i te whatukuhu, me te ate ki te auautanga o te 1-2 wa ia e rua nga marama.

A, no te tukinotia psoriasis te, tonu te therapy te i te tono rohe o te tarukino.

Ki te pa koe ki te tuwhena rawa, me tomo te manawanui he Wharangi o te konupūmā i roto i nga haora tuatahi e wha.

Ngā pāhekoheko ki ētahi atu taero "methotrexate"

"Methotrexate" riria ki te whakamahi ki te rongoā e whai ake nei:

- drugs kore-steroidal anti-inflammatory;

- paturopi rongoā paturopi;

- sulfonamides;

- waikawa valproic;

- colestyramine;

- mercaptopurine;

- neomycin;

- paramomitsinom;

- omeprazole;

- retinoids;

- tetracycline;

- cyclosporine.

Ko nga contraindications "Metodzhekt" o ngā rongoā me te "Methotrexate" enei. He aha te mea te rerekētanga? Reviews whakaaro e kua whakawhiti ratou rite pakeke.

Ngā pāhekoheko "Metodzhekta" ki ētahi atu tikanga

fariiraa tukutahi "Metodzhekta" me ētahi atu taero arata'i rānei ki nui haere te tāoke, ki te whakaiti i te pānga haumanu ranei. Ki te hiahia koe ki te ngā i tetahi tikanga, he pai ki te whakamōhio i te mātanga.

"Metodzhekt" tangohia ki tūpato ki:

• raau taero Hepatotoxic.
• Drugs, toto nanakia.
• Drugs e pā te hinu wheua wheua.
• inu i te kava.
• Paturopi.
• NSAIDs me salicylates.

rārangi rāhuitia o ngā rongoā he nui nui. Me mahara te reira kia e te pāhekoheko ki te "Metodzhektom" Ka meinga poisoning paitini rawa taimaha o te tinana (kore te mate waho). I te tahi taime e taea arahi reira ki pukupuku kiri.

tea Green me kawhe e rāhuitia hoki, me te inu i te pāhare purine, theophylline me te kawhe. Ko te take mo te taua - hototahi kino ki methotrexate. Ka taea e tino whakaroa te reira i to ratou tango.

Me kï reira e ka te fariiraa therapy whakaatu complexes huaora me teuteu kei roto folate, no te mea te whakaiti ratou nga āhuatanga paitini.

E tarukino ki te whiriwhiri - "Metodzhekt" me "Methotrexate"? I te mea pai? I runga i tenei i muri mai.

pānga taha

kia rerekē pānga taha, engari te nuinga o maha pā whekau o te wahi gastrointestinal. whakatika ratou ki te auau me te pakeke, i runga i te horopeta me nga āhuatanga takitahi o te rauropi rānei.

Puta e te nuinga pānga taha:

• Stomatitis.
• Whakapairuaki.
• Depression.
• Anemia.
• Dermatitis.
• Ānini me te whanoke.
• sweating nui me te kirika.
• Mate pāwera, me te ru anaphylactic.
• Pericarditis.
• Thromboembolism.
• kakā interstitial.
• Tini o nga mate hopuhopu.

ētahi wā:

• Ruaki.
• Alopecia.
• Vasculitis.
• Pharyngitis.
• Paresthesia o te raro wahi, maihao, me waewae.

Tino onge:

• Haehae, me te pāpāngia.
• Visual waimaerotanga.
• iti hoki pūkahukahu.
• Myalgia.
• Osteoporosis.

Kia whakawhanake pancreatitis, mate huka, paruparu, pākoko, me ara taea te putanga o te pukupuku.

He aha te mea te rerekētanga i waenganui i Metodzhekt te raau taero ' "me" Methotrexate "? Ko tenei pātai o te moni ki tokomaha.

Kia tino ki te whai whakamātautau auau ki te hunga tūroro e te tukinotia "Metodzhektom". Ko te kupu e taea te ārai te reira haurangi. hopearaa nui o tenei whakamataku, pea mate.

Rāhuitia taraiwa i roto i therapy me te mahi ki te mīhini mōrearea.

Next, whakaaro te pānga taha o raau taero pērā i "Metodzhekt" me "MTX". He aha te mea te rerekētanga i waenganui i a ratou?

pānga taha "methotrexate"

I runga i te wahi o te pūnaha kūnatu kia mau faaiteraa o stomatitis ulcerative, anorexia, Gingivitis, pharyngitis, whakapairuaki; i roto i te wā onge - korere, melena, enteritis, pancreatitis, necrosis ate, cirrhosis, atrophy ngako, kakakīrehe periportal.

Ka taea e te pūnaha hematopoietic whakautu leukopenia, anemia, thrombocytopenia.

pūnaha Central io - rohirohi, whanoke; i roto i te wā onge - ānini, aphasia, sleepiness, haehae.

pūnaha whakaputa uri - he takahi o oogenesis me spermatogenesis, oligospermia, kōtītiti paheketanga, heke libido, paruparu.

pūnaha mimi - hematuria, cystitis, nui mahi waimaero tākihi.

Ka taea e faaite mai i te tauhohe e whai ake nei mate pāwera: kirika, ātete heke ki te mate; i roto i te wā onge - urticaria, necrolysis epidermal paitini, Stevens-Johnson syndrome.

tauhohe Dermatological - ponana kiri, photosensitivity, disorders ähua, hakihaki, whewhe.

A, no te tetahi tauhohe kino ki te tarukino kia whakapā tonu te rata.

tuwhena rawa

Ko mōrearea ki te pūnaha hematopoietic He tuwhena rawa. I roto i enei take, i te rauropi ko te hydration. Ka taea e tere ake tenei te excretion o te taonga kaha. whakaritea hoki ki te farii i waikawa folic.

Here me ngā

whakaaro tatou "Metodzhekt" me "Methotrexate". He wātea hoki te rerekētanga i roto i te ora papa.

Ko te maroke, wahi pouri i te pāmahana e kore rawa te 25 nekehanga, kia mau enei rongoa. Kia tino ki te horoi atu i ngā tamariki. Te rā me te makuku e contraindicated ratou. Whakatio taea ratou.

"Metodzhekt" ere mō te 2 tau i te rā o te hanga, "Methotrexate" - 3 tau.

Enei rerekē "Metodzhekt" me "Methotrexate". He aha te mea te rerekētanga ano?

I roto i te rite ki "Metodzhektom", ka taea e koe te tīpako i etahi o te kounga motuhake o "methotrexate". He pānga te taha taea, engari, i roto i te whakaaro o tūroro, puta iti pinepine. "Methotrexate" he wātea i roto i te papa ano, mo tūroro tokomaha, he atu watea tenei puka.

Na, kua whakaahuatia matou i roto i te taipitopito te whakamahi o "Metodzhekt" raau taero, me "Methotrexate". He aha te mea te rerekētanga, ko reira inaianei mārama.