Ko te tarukino "El-Thyroxine": tohutohu mō te whakamahi, analogs, arotake

Drug "Al-thyroxine" - waihanga taiki thyroid, thyroxine orotahi o te taiao. Ki runga ki te fariiraa i te medicament ko te faafariuraa kanohi o thyroxine ki triiodothyronine, iodo taiaki wāhi e te i roto i ngā tukanga pūkoro katoa me he mana nui i runga i nga mahi o whekau maha. whakamahia te raau i roto i te wā i reira tino heke thyroid mahi.

whakaaturia Taupānga o te medicament te i muri i tango o te repe thyroid me tona pihi kiko ka kore te waimaero repe mahi. I te tahi taime whakaritea rongoā te ki te iwi nei i piki thyroid mahi, engari i te tuatahi te mahi therapy ki pehi te secretion o hormones iodine-kei roto. I roto i taua tūroro, i muri i te tono o te "El-Thyroxine" tāmia tukanga whakatupuranga TTG wāhi nei i roto i te kōtuitui o thyroxine.

kai tarukino tuku Puka

"El-Thyroxine" he wātea i roto i te papa. Ko te taonga kaha he levothyroxine konutai. Ko te hanganga o te tarukino taea tapae he maha rerekē o ngā wāhanga taketake, te raau e tika ana whakaritea e te tākuta. kai Ngaahi Houalotú aroaro konutai māngaro glycolate, konupūmā hauwai Phosphate dihydrate, roa-mekameka glycerides wāhanga, dextrin me te microcrystalline cellulose. Rerekē kaiwhakanao hanganga o kai ngaahi houalotú kia rerekē paku.

Pharmacodynamics, pharmacokinetics, "El-Thyroxine"

Ko te whakauru mātātoa o te tarukino me te thyroxine, e putanga puta i roto i te tinana, e mahi ana i te kotahi te mahi. "El-Thyroxine" whai wāhi ki te māori o ngā tukanga pūkoro tinana, nga tukanga o te whanaketanga me te tupu. whakaritea te mahi o te raau taero e te ihirangi o te taonga kaha. Ko te whakamahi o pota iti "El Thyroxine" arata'i ki te whanaketanga o te pānga anabolic, teitei - Me ki ake i pūtau me te kiko hāora tono, te whakaongaonga o ngā tukanga oxidative, tere pākia me te rärangi o te warowaihā, pūmua, te ngako. I tua atu, i pota tiketike whakahohetia te tarukino te pūnaha io pokapū, pūnaha Cardiovascular.

tīmata te medicament ke ngāue muri e pā ana ki e rima nga ra i muri i te tono tuatahi. Hoki e toru ki te ono nga marama o te maimoatanga tonu he taea ki te pehea o te goiter E ruia ana ranei whakaiti i tona rahi.

Absorption e wahi te nuinga i roto i te kōpiro iti rite ki te hua o te fariiraa i papa nohopuku he kore neke atu i te 80%, me heke te whakamahi o te kai te. Well hono ki nga pūmua wē, "El-Thyroxine", te parau tohu e te hononga ko tata 100%, na e kore e te tarukino pā rānei tātari toto hemoperfusion ranei.

whakaritea te kukū mōrahi o te wāhanga matua kei roto i te tinana i muri i rima haora i muri i ingestion o te tarukino. tango Motunga o te tarukino i roto i ngā tūroro puta i roto i ngā huarahi rerekē, i runga i te taumata o hormones thyroid i roto i te tinana rānei.

I roto i te hypothyroidism kawea ona tango i roto i roto i iwa tekau ranei nga ra, ki euthyroid - hohoro atu ono ranei e whitu, thyrotoxicosis hawhe-ora rere - i roto i te toru ranei wha ra.

Tata kotahi-toru o te whakauru matua horopeta rongoā takoto i roto i te ate, i te tuhituhi pāhekoheko tere ki thyroxine i he reira i roto i te toto. Puta i te reira i te hanganga o metabolites i muri i ingestion o papa "El Thyroxine". Tohutohu mō te whakamahi o ngā pūrongo e whakamana pākia tuatahi o te wahi tarukino e i roto i te roro, uaua, tākihi me te ate. Excretion o metabolites whakaputaina e te whatukuhu, me te paru.

Tuhinga hoki te whakamahi o te faaineineraa "El Thyroxine"

hāngai ana maimoatanga whakauru i runga i te whakamahi o tenei tarukino whakaritea ki tūroro ki āhua hypothyroid o etiologies rerekē, t. H. Hypothyroid (tuatahi, tuarua) tupu i muri i te mahi, me te āhua i whakapataritari e te tikanga fariiraa e e tito o radioiodine . āhei "El-Thyroxine" ako i runga i te tono ki a koe tautapa i roto i te wā e whai ake nei:

• mate cerebro-hypophyseal;
• Hypothyroidism congenital ka riro;
• tenga euthyroid;
• mate o Hashimoto, Graves 'mate (maimoatanga i roto i te matatini);
• ki tohumate o te mōmona hypothyroidism cretinism ranei, tahi e te taua āhuatanga;
• hyperplasia euthyroid (huinga therapy);
• goiter nodular recurrent i muri resection i roto i te disorders ngaro repe (papa whakamahia rite te medicament prophylactic);
• puku repara (whakauru me te therapy suppressive);
• neoplasms, e kua āhuatanga rite tino rerekëtanga, taiki, i te āhua mārere.

Rongoā e whakamahia ana ki te mahi i whakamātau tātaritanga. I te tahi taime te tango iwi "El Thyroxine" whakaitiiti te ngaro o ngā raruraru ki te repe thyroid, engari e kore e kaiwhakaako whakapai ana o te whakamahi o te medicament mo te whakaaro taua.

Contraindications ki te farii i te tarukino, "El-Thyroxine"

E kore te te medicament whakahaere ki tūroro ki te tūtohutanga ki ona wāhanga. Contraindications ngā:

• infarction myocardial (atamira whakapeka);
• rere gipokortitsizm mua kāore thyrotoxicosis ranei;
• mumura o te uaua ngakau āhua whakapeka;
• galactosemia tuku;
• syndrome, e poka ki absorption i te whēkau;
• hē lactase.

whakamahia te raau i te tūpato i roto i te tūroro ki te mate huka mellitus, ka pakeke e rerengia ana hypothyroidism, i te mea he roa te wa i kore tukinotia, me mate e pā ana ki pāpaka Cardiovascular:

• sredtsa mate ngakau coronary;
• takawhita;
• arrhythmia;
• infarction myocardial (hītori);
• atherosclerosis.

Ki te he te manawanui etahi o enei mate, heke te horopeta e ranei te orotahi tīpakohia.

therapy

I roto i te maimoatanga, kua tīpakohia takitahi te tikanga o "El-Thyroxine" pota mo ia manawanui e hāngai ana i runga i ngā taunakitanga. e kore e papa tararua, inu i runga i te puku kau, i te iti rawa te 30 meneti. i mua i te kai. Tūroro ki mate o te pūnaha Cardiovascular me kua tae rima-rima tau i runga i te 1 kg o taimaha e whakaritea te mōrahi o 0.9 mg o te tarukino. Ko te toenga whakaaturia i 1.6 .mu.g ki 1.8. I te wāhanga tuatahi o te maimoatanga, te horopeta tūtohutia o te tarukino mō ngā tūroro ki hypothyroidism e whai ake nei:

• Tūroro e whai raruraru ki te pūnaha Cardiovascular, te raau whakaritea i 75 mcg ki 150, e hāngai ana ki te horopeta ia rā.
• I roto i te pāpaka Cardiovascular, me te ki tūroro pakeke whakahaere te tarukino i roto i te nui o 25 g. I muri e rua nga marama nui haere te horopeta ki te 50 mcg. I muri mai, tenei huringa tawhā ki taua wā, te whakanui ake ki te 25 g, whakaritea ra ano te mea nui tino arotau o te waihanga me te TSH kore noa.

Me pēhea te ki te hanga "El-Thyroxine" i roto i te wā rerekē, he mea e tika ana ki te mohio ki te tākuta. Ki te whiwhi kino te huru o te oko, me te ngakau, he mea e tika ana ki te whakahou i te tikanga mo te maimoatanga o mate o te pūnaha Cardiovascular.

A, no te hypothyroidism congenital whiriwhiria āhua o te horopeta o te tarukino e rite ki tau. Ko te tūroro iti rawa (ki runga, ki te 6 marama) whakahaere 25 micrograms tarukino, engari kaua e nui atu i te 50, ko te inenga rā e hiahiatia ana i te 10 ki te 15 micrograms ia kirokaramu. Tamariki i raro i te tau o kaua e nui ake te 1 tau, whakarite 50 mg ia kg. Ki te ko te tau o te manawanui i roto i te whānuitanga o tetahi ki te e rima nga tau, te horopeta iti ko 75 mcg, engari kaua e nui atu i te 100 micrograms. I muri i te ono tau o te tau (tamariki i raro i te 12) whakaaetia te ki te whakamahi i 100 moni mcg kore rawa te horopeta o 150 mcg. Ētahi atu tamariki e hiahiatia ana horopeta tīpakohia te i roto i te whānuitanga o 100 ki te 200 micrograms.

I roto i therapy, rongoā, "El-Thyroxine", rite korerotia i roto i nga tohutohu mō te whakamahi mō ngā tamariki i raro i toru tau o te horopeta ia rā te tikanga hoatu kotahi. I muri i kai whakahaere tarukino taea te kawea i roto i roto i te hawhe haora. I roto i te maimoatanga o tamariki taitamariki whakamahia te otinga rite i papa.

I roto i te nuinga o te wā, iwi e mamae i hypothyroidism, tangohia rongoā mo te ora. Ko te hunga e whakakitea thyrotoxicosis, i muri i te whanaketanga o euthyroid kāwanatanga "Thyroxine" tohutohu ki te whakamahi i roto i te taha ki te antitireoidinymi tikanga mo te wā i whakaritea e te tākuta.

Ko te whakamahi o te tarukino mō te ngaronga taimaha

Ki te pehea e taimaha te taikaha te whakamahi i 50 micrograms ia te tikanga ra. Te whakamahi horopeta rā o rua kaupae e Me kawea atu i roto i te ata. Fakataha ki te tikanga "El Thyroxine" tango β-pūārai i roto i te inenga tīpakohia e hāngai ana i runga i te auau he pini. I roto i te horopeta anō tukua mārō "Thyroxine" ki 150 micrograms. Whakanuia te horopeta āta, i muri i te tikanga te hua o te fariiraa e wehea ki toru nga wa. I roto i tenei take, kia kawea te tikanga muri i roto i kore i muri atu i te 18:00. Ano, ake i te horopeta β-pūārai, whiriwhiria te nui e tika ana o te raau taero e takitahi, i tere ngakau okiokinga kia i te whānuitanga o i 60 ki te 70 kapakapa ki te meneti.

I te tahi taime Me ki whakaiti i te horopeta tikanga "Al-thyroxine" koe. pānga te taha tohu te hiahia ki te whakakore te whakaiti i te horopeta tarukino ranei. kia muri i te akoranga e pā ana ki te marama, e kore e tangohia te rongoā roa atu wiki e whitu.

Kaua e koimutu whakarerea te whakamahi o te raau taero, hua āta tona Tuhinga, āta whakaiti i te horopeta ki wā e rua-wiki. A, no te te korere ko atu inu kaihoko "Loperamide" i roto i te kotahi e rua ranei capsules rā. A tapiti faahou i te akoranga e hāngai ana i te whakaiti taimaha, e toru ranei e wha wiki i muri mai e taea e.

pānga taha pea

kia puta etahi tauhohe kino i roto i te maimoatanga ki "Al-thyroxine". He tino onge pānga taha ka whakamahi i te tarukino i te pota taunakitia. No te mea o kia whakanui i taimaha te hiahia nui haere, ka taea e makawe hinga i roto i, ko reira taea te putanga o ngā raruraru ki nga whatukuhu. Tamariki ki te haurangi, me te kaha ake te tūpono o hukihuki, ka taea e te mate kia atu kino ki te nui koe i te huinga dose "Thyroxine". I roto i te maimoatanga ki pota tiketike he pea e te whanaketanga o ngā tohu o te hyperthyroidism.

I roto i te tahi atu pānga taha - manukanuka, disorders manukanuka, te ahua o te e alangá faaati, raruraru moe, tohu o arrhythmia me tachycardia. Ano, i reira kia kia mate taimaha me te whanaketanga o te korere, aroaro o ruaki. Mahalo sweating, aroaro o tohu e haere tahi i te whawhai o te pectoris angina. Ētahi tūroro i te dermatitis pāwera. Ki te whanaketanga o tauhohe kino o te tinana o raro horopeta "Thyroxine" ranei poto whakakore i te tarukino, me te muri whakamahi i te horopeta iti.

Ko te huinga o te tarukino me te waipiro

Tikanga, he horopeta kotahi o te nui iti o te waipiro i te pa iti e kore mana i runga i te pānga o te kaihoko "Al-thyroxine". whakaatu Reviews e inu waipiro i roto i te maimoatanga kia anake te hunga iwi e kahore raruraru ki oko toto, me te ngakau. I roto i te tahi atu te wā, te huinga o te raau taero i te waipiro arata'i ki hopearaa houhou. Pea e kore e whakaiti anake te whai huatanga o te therapy, engari ano hoki he takahi o te ate, te pūnaha io pokapū.

analogues Drug "El-Thyroxine"

O analogs hanganga hei utu o "Al-thyroxine" taea te whakamahi "Eutiroks", "Bagotiroks". Ko te tarukino tino maha tīpakohia "Eutiroks" e he tohu ōrite, contraindications me inenga. Mai i "El-Thyroxine" e rere ke te reira anake te taha o te kukū o te taonga kaha. Ki te kore te mea e tika ana te manawanui, i whakaritea "El-Thyroxine" analogues tohunga tango ki peculiarities pūkete o te rauropi.

Reviews o te faaineineraa "El-Thyroxine"

I roto i te arotake, korerotia ana e ia e te tarukino, i te whakamahia i roto i pota iti whakatairanga tahunga ngako e tika ana ki te whakatere o pākia, pehanga o te hiahia me te whakapiki ake i whakapaunga caloric. Whakaititia te ahua o ngā pānga taha ārai ratou awhina whanaketanga ki te β-blockers ranei. whakaatu Reviews e maha ngā te rongoā ki taua tikanga. Ahakoa te meka e "Thyroxine" maha āwhina ki te ngaro taimaha, te whakamahi i te reira no te ngaronga taimaha e kore e tūtohu. No te iwi hauora, ka taea e te rongoā e kino.

I roto i te maimoatanga o mate e pā ana ki te mahi thyroid waimaero, te tikanga he whai hua te tarukino, rite kitea e te arotake. Whakaahua ana i te taputapu arata'i ki toenga noa o hormones, na nga tūroro ite pai. He arotake kino no te mea i ētahi wā whakawhanake ngā pānga taha. Ahakoa te kaha ki te meinga i te maha o ngā tauhohe kino te tarukino me te, tautoko reira te thyroid, ai te mahi tikanga i te tinana.

Mā te whakamahi i te "El-Thyroxine" i runga i te wā e taea te nekehia atu i te mate thyroid mate whakaiti i te pakeke o ngā tohu puta noa i to ratou oraraa ranei.