Ko te tarukino "Remicade": tohutohu mō te whakamahi, tūturu

Tōtika te tikanga "Remicade"? Tohutohu mō te whakamahi, arotake manawanui o tenei rongoā ka kia te aroaro i raro. Ano i roto i tenei tuhinga, ka ako e pā ana ki a koutou i roto i tetahi take, whakahau te raau taero, ahakoa kua ia contraindications me ngā pānga kino, e he wahi o reira wāhanga, me te pera i runga i.

Puka, hanganga

tukuna faaineineraa "Remicade" kei roto i te puka o te paura lyophilized tikanga mo te faaineineraa o te otinga e whaowhia. Ko te whakauru mātātoa o te tarukino he infliximab. Kei reira hoki ngā wāhanga atu rite polysorbate 80, te konutai hauwai pākawa dihydrate, sucrose me monohydrate konutai dihydrogen Phosphate.

āhuatanga matua

He aha te mea te rongoā "Remicade"? kī Tohutohu mō te Whakamahi i te mea he kaihoko immunosuppressive.

E puta i roto i te tinana, ka tīmata te tarukino ki te taunekeneke ki te puka wairewa me transmembrane o puku necrosis ārepa (TNFα), whakaiti ratou mahi i te hanganga o te matatini pūmau.

tohunga rangahau whakaaro e te taonga tarukino kaha te whakaiti kookuhutanga pūtau (inflammatory), me te maha o tohu inflammatory i roto i te wāhi pāngia o te whēkau. Ko te kupu i reira ko te whakaora tika tere o te membrane mucous.

Pharmacokinetics

He aha e kua te tawhā pharmacokinetic rongoa "Remicade"? Note, āhua urupare e te werohanga rō-uaua kotahi o te infliximab i roto i te nui o runga ki te 20 mg / kg aru e te hua hautanga i roto i tona kukū mōrahi.

tono toutou o te tarukino ai te haaputuputuraa iti o te taonga kaha i roto i te serum.

kore kua ara o whakakorenga o te tarukino i tāutuhia.

Tuhinga

Hoki te aha kia whakaritea ai ngā take tarukino "Remicade"? whakaaturia te whakamahi o tenei rongoā i roto i te wā e whai ake nei:

• kaikōiwi i roto i te puka hohe (ki te i hua tūroro tukinotia taketake taero antiinflammatory). kawea therapy i roto i roto i ngā ki "methotrexate". Tenei huinga taea hoki te whakaiti i te tohu o te mate, me te te whakapai ake o te tahi e rite ana te katoa.
• mate o Crohn i tūroro pakeke. I roto i tenei take e tauturu te reira ki "Remicade"? kī Guide e kia whakahaere therapy ki tenei faaineineraa i roto i te take o te ātete memeha noa ranei, engari ano ki te contraindications ki te tarukino paerewa. I roto i taua tātaritanga "whakatairanga Remicade whakakorenga o tohu mate katoa, te pupuri murunga me te whakaora tere o patunga, fistula kati me te whakapai ake i te huru o te manawanui.
• mate o Crohn i roto i taiohi. kawea te rongoā ki tenei tarukino i roto i roto i te take o te ātete memeha noa ranei, engari ano ki te contraindications ki te kaupapa paerewa o te therapy. Medicament "Remicade" whakaiti tohumate me tautoko murunga me te whakapai ake i te kounga o te ora o tūroro taitamariki.
• colitis ulcerative i roto i ngā pakeke. Drug "Remicade", e Reviews aroaro i raro, e faaterehia i roto i te kaupapa i he hua therapy tikanga. Maimoatanga o tenei kaihoko te whakaiti i nga tohu o te mate, te mucosa intestinal whakaora, whakaiti Tuhinga ranei o toketaá GCS. Me mahara hoki käore te reira e, i muri ohipa o te taputapu faaore te hiahia mo te noho hōhipera.
• colitis ulcerative i roto i ngā tamariki. Maimoatanga ki tenei tarukino whakaritea ki ngā tamariki 6-18 nga tau te pakeke, ki te mohiotia therapy tikanga hua.
• spondylitis Ankylosing (ki koretake therapy paerewa). Ka rite ki ki te tātaritanga āwhina rongoā "Remicade"? Tohutohu mō te whakamahi pūrongo e whakaiti tenei taputapu nga tohu o te mate, me te whakapiki i te mahi o te hononga iho.
• Psoriasis (ki koretake therapy paerewa). Ka rite ki i roto i te psoriasis āwhina "Remicade"? tohunga te āheinga mea e whakaiti tenei raau mumura i roto i te kiri, me te normalizes te tukanga o te keratinocyte pārōnaki.
• rumati Psoriatic (mō te koretake therapy paerewa). Ko te medicament "Remicade" faaterehia i roto i ngā ki "MTX" rite monotherapy ki contraindications ātete ranei ki te muri ranei. Ka rite ki te hua, heke te maimoatanga nga tohu o rumati, ake tūroro mahi mahi, me te heke te tohu o te haereraa radiographic i roto i te rumati psoriatic.

contraindications

Treatment "Remicade" rāhuitia whakahaere ina:

• nui tukanga hopuhopu (hei tauira, sepsis, whēwhē, kohi, mate kapo) ;
• nui haere te tūtohutanga o te manawanui ki te infliximab me te pūmua murine me tetahi atu wāhanga o te tarukino;
• i raro i te tau o te 6 tau (colitis ulcerative me mate o Crohn);
• hapūtanga;
• rahunga ngakau;
• i raro i te tau o 18 tau;
• ū.

Drug "Remicade": tohutohu mō te whakamahi. A i reira ki te tomo (ki te anake i roto i te hōhipera)?

kia rongoā i Tirohia kia whakahaerea anake i raro i te mātakitaki o te mātanga (arā hōhipera) e kua te wheako rawaka o te tātaritanga me te maimoatanga angitu o te mate i runga ake.

whakaurua te otinga te dropwise pâmuhia runga 120 meneti. E kore e te auau e teitei ake i te 2 ml ia meneti. Whakatinana i ngā tukanga e tika ana ki te whakamahi o te pūnaha whaowhia.

Ko te inenga o te raau taero tei runga i te taunakitanga.

kaikōiwi

I roto i taua mahi tātaritanga kia horopeta tuatahi e pā ana ki 3 mg ia kg. whakahaere te medicament te toutou i 3-6 wiki. Na ka whakamahi i te reira nga rua marama.

I roto i te kaupapa e kore kua tutuki te pānga haumanu, whakaaro te mutunga o te therapy.

Ko te tikanga i te tarukino ko "Remicade" ki kaikōiwi whakahaere tahi me te "methotrexate".

colitis ulcerative

inenga tuatahi, ka taua tātaritanga ko 5 mg ia taimaha tinana kg. whakahaere te taua horopeta o tarukino te 3-6 wiki i muri mai. Katahi ka kawea te maimoatanga i nga rua marama.

Ki te tika, e taea te nui haere te horopeta ki te 10 mg ia kg. Kei te nuinga o te wā i kite te pānga o te maimoatanga i roto i 14 wiki. I roto i taua take, ki te kahore he reira, kia haere tonu koe maimoatanga.

rumati psoriatic

Psoriatic rumati tarukino "Remicade" faaterehia i roto i te horopeta tuatahi o 5 mg ia kg. whakahaere te medicament te toutou i 3-6 wiki. Na ka whakamahi i te reira katoa 7-8 wiki.

Whakahau taea te ngā rongoā ki "methotrexate".

mate o Crohn

I roto i taua tātaritanga mō ngā pakeke e whakaaturia pota kotahi o 5 mg ia kg. Ki te kore i tutuki te pānga haumanu mo te mua 2 wiki, hurihia te tarukino.

Ki te he mahi tarukino pai, nga kaupapa e whai ake nei:

• whakahaere te otinga i roto i te horopeta taua rite i roto i te e whaowhia tuatahi, a i muri i 3-6 wiki te makamaka. I muri i taua, kia te werohanga katoa e rua nga marama. Ki te hiahiatia, e taea te nui haere te horopeta ki te 10 mg ia kg.
• whakahaere te raau e anake i relapses ki te kore pakeke atu i te 16 wiki i muri i te whakamahi tuatahi.

mate o Crohn i roto i ngā tamariki taitamariki

Crohn āhua ranei nui i roto i ngā tamariki i raro i te 18 tau Ko tā te whakamahi o te horopeta tuatahi o 5 mg ia kg. Me mahi werohanga muri i roto i te 3-6 wiki. Katahi ka whakamahia te rongoā te katoa e rua nga marama, ki te hiahiatia, whakaritea ki te inenga o te 10 mg ia kg.

Tikanga, ngā te raau e ki immunomodulators 6-mercaptopurine, "azathioprine" ranei "methotrexate". Ki te kore i tutuki te pānga haumanu (mō te 10-11 wiki), te whakamahi o te tarukino he houhou.

tahi mate o Crohn e fistula

He horopeta kotahi o te tarukino i taua tātaritanga ko 5 mg ia kg (i roto i ngā pakeke). Rongoā te makamaka i muri i 3-6 wiki. Ki te te kore kitea te pānga haumanu i muri i te 3 werohanga, he tika ka atu maimoatanga.

Ki te pānga pai o te raau taero, te kaupapa e whai ake nei:

• reintroduction i muri i 3-6 wiki, me te ka nga rua marama;
• whakahaere te medicament te i matahoki ki te tangohia e te reira iti iho i te 16 wiki.

spondylitis ankylosing

Ka rite ki ki te whakamahi tarukino tātaritanga "Remicade"? Tohutohu mō te whakamahi āhua i roto i tenei mate kia inenga tuatahi o te tarukino 5 mg ia kg. I muri i tenei, faaterehia te raau e i muri i 3-6 wiki.

e kore e kia tonu te rongoā ki te, i roto i te ono wiki kahore he kite te pānga.

psoriasis

I roto i te maimoatanga o te psoriasis tīmatanga horopeta ko 5 mg tarukino ia kg. tono toutou o te medicament whakahaeretia i muri i 3-6 wiki, a ka - kotahi katoa waru wiki.

Tukanga mō te faaineineraa o te otinga whaowhia

kia rite te otinga e whai ake:

• Tātaitia te reira i te horopeta me te maha o oko.
• rewa te paura tarukino i roto i te 10 ml o te wai mā te whakamahi i te pūwero. Ki te mahi i tenei, te tango i te pōtae pounamu whakarewa (kirihou), ka muru i te puru ki te waipiro. whakaurua te ngira te roto i tona pokapū, ka arahina te inu e i roto i te taiepa.
• I āta whakaohokia te otinga (kaupapa hurihuri) rewa ra ano te te puehu. kia rānei taekore kauruku kōwhai ranei Drug wai. Ki te i roto i te pahuka i pounamu ranu i hanga, he mea e tika ana ki te infuse te otinga o te 5 meneti. pea te puka inenga whakamutunga reira matūriki pai translucent.
• whakaritea te rōrahi katoa o te rongoā te ki 0.9% pūhaumāota (250 ml) o te wairewa konutai. Hoki tenei whakaaro kua tapiritia te wai rite ki te pounamu, e kei kē konutai pūhaumāota. Kei te ata i konatunatua rua wāhanga.
• kawea Omuaraa o te faaineineraa i roto i kore i muri atu i te 3 haora i muri i te faaineineraa o te otinga tarukino.

Kei te riria te reira ki te tomo i te tarukino ki ētahi atu māngai i roto i te pūnaha taua. Ki te mea i reira he taonga ke ranei matūriki puatakore i roto i te otinga, e kore e tūtohu ana.

nui kāore o te tarukino ki kia whakamahia.

pānga taha

A, no te whakamahi i te medicament, te tauhohe taha e whai ake:

• korekore, tau'a, nui haere manukanuka, whanoke, somnolence, pau te, mate wareware, āhotea, ānini;
• edema pūkahukahu, pakohu kakā, bronchoconstriction, dyspnea, mate pāwera, kakā, epistaxis, Bronchitis, pleuritis;
• pīkaru, keratoconjunctivitis, endophthalmitis;
• ngawhatanga me mimi mate;
• tai, te ngangau i o tohanga piringa, bradycardia, ecchymosis, kanokanototo, mamae iaia, syncope, palpitations, cyanosis, petechiae, arrhythmia;
• thrombocytopenia, anemia, neytrotsitopeniya, leykotsitopeniya, lymphopenia, lymphadenopathy, lymphocytosis;
• cheilitis, kōroke, cholecystitis, Reflux, diverticulitis, korere, whakapairuaki, tokopā, mahi ate waimaero;
• ponana kiri, kiri maroke, alopecia, seborrhea, minamina, abrasions, hikaka, sweating nui haere, dermatitis, fungal, kiritona, hyperkeratosis, erysipelas, he takahi o ähua kiri, hūnga bullous.

Reviews o te faaineineraa

Na e matau ana koutou ki te whakamahi i te tarukino "Remicade". kua tohutohu hoki te whakamahi o te raau taero kua whakaahuatia ana i runga.

I roto i te nuinga o te wā, whakaaro he tikanga ki te akakoromaki i te mahi. Na reira, i kitea te nuinga pai urupare i ngā tūroro. People e whakamahi tenei otinga, penei, i muri i te haere tata rawa te werohanga o te mamae. Heoi, he wehi o te ti'aturiraa i te tahi mau tūroro, ka taea e meinga ai.