"Nebilong": tohutohu mō te whakamahi. "Nebilong": arotake me analogues

"Nebilong" Ko te tarukino whai hua mo te maimoatanga o mate e pā ana ki te mahi waimaero ngakau. mahi whakapai ake i muri i te whakamahi i te reira mo te kotahi marama. I muri i tono "Nebilonga" pini tonu o me te pēhanga toto, tae whakangā iaia te, tukua te myocardium te rawaka hāora. I roto i te tata wā katoa puritia te hua pai o te therapy te mo te wa roa.

Composition, Composition

E wātea ana i roto i te papa i te rongoā. Ka taea e roto i ia papa 2.5, 5 ranei 10 mg o whakauru kaha. hanga ana te rongoā i runga i te pūtake o te nebivolol hydrochloride. O te excipients reira i roto i te hanganga o te povidone, reihuka, konupora stearate. Composition kō atu ki talc, microcrystalline cellulose, konutai dioctyl pūkawa, te hauhā silicon colloidal, te konutai croscarmellose, Beta-cyclodextrin.

pānga pharmacological

"Nebilong" whakaaturanga ako ā-rite te tikanga he i roto i tona hanganga e rua poinanaha (L- me D-nebivolol). D-nebivolol - tino whiriwhiri, whakataetae pūārai β1-adrenoceptor, L-nebivolol ngawari i runga i oko toto, fakalahi ratou, i te mea e tika ana ki te tukanga i roto i te endothelium iaia (tuku vasodilating tauwehe puoro).

Nebivolol whakaiti pēhanga toto me te auau ngakau, kei te rongoa te hua e kore anake i roto i te āhua āta engari ano i raro i kawenga. I muri tango i te rongoā a tawhio noa, a kua heke tenge ventricular maui mutunga-diastolic, i reira te mea he pānga pai ki runga ki tetahi o nga mahi i mahi e te ngakau - diastolic. No te mea tono o te piki ejection hautanga "Nebilonga", iwi ki IBS tohua pānga antianginal.

whakamārama mahi Hypotensive tangohia papa "Nebilong" aratohu te heke i roto i te mahi i roto i te pūnaha renin-angiotensin. tutuki mahi Antiarrhythmic e whakaiti i te AV-āriponga, me te pehi rerekē ngakau automaticity. puta Paturuhia pānga hypotensive i roto i 7-14 ra o te maimoatanga, maha - i roto i te marama. hua pūmau i i tango papa kitea i muri i tetahi ki te e rua nga marama o te maimoatanga.

Pharmacokinetics

Te raau ingested, whenumi pai, he rite whai hua te tukanga ahakoa o te kai. Pākia i roto i te ate, me whakaoti te hanganga o te gidroksimetabolitov kaha. Ko te bioavailability toharite i muri i tono o te tangata medicament ā-ki te pākia e tere o te 12%, he nui ki runga ake i ki pākia puhoi tenei ahua. Mai taea te pākia o tūroro puta i reiti rerekē, tūtohutia "Nebilong" ā-ringa mō te whakamahi ki te āhuatanga takitahi o te tinana o te manawanui. Ki te pākia puhoi e whakamahia pota iti o te tarukino. I roto i ngā kaupapa ki te utu tere o matū e wahi hawhe-ora o āhua 10 haora, i roto i tūroro e whai i te pākia e puhoi, hawhe-ora nui haere e 3-5 wā. I muri i nga ra e whitu o te therapy, e pā ana ki 38% riro te raau excreted e nga whatukuhu, e pā ana ki 48% "Nebilonga" Ko reira i roto i te kumete. Ko te hanganga o te mimi ko te nui iti o te rongoā tonu - ki runga ki te 0.5%.

iteraa papû

I runga i te tono o "Nebilong" ako taea te whakamahi mō te takawhita, mo te whakatinanatanga o āraihia i roto i te tūroro ki te CAD (pāngia o angina) me mo te whakatinanatanga o te therapy matatini o te kore ngakau o te puka ma'i.

Treatment ki te tarukino "Nebilong"

takawhita

tūroro pakeke whakahaere 5 mg "Nebilonga", e hāngai ana ki te waihanga papa ko te horopeta ia rā. tūtohutia te rongoā te ki te whakamahi i ia rā i te wa ano. he kite i muri i tetahi ki te e rua wiki o therapy, te tino korerotia te pānga iti, ko ia he marama i roto i i whakamana i te maimoatanga te. Papa e tika ana mō te whakatinanatanga monotherapy me mo te maimoatanga e hāngai ana i runga i te whakamahi integrated o taero, ano e whai pānga hypotensive. Iwi e tango "Nebilong AM", te ako tūtohutia i roto i te tikanga ki te whiwhi i tētahi pānga atu ki te tono "Hydrochlorothiazide" o 12.5-25 mg. Ka taea e taua maimoatanga ngā whakarei i te mahi o "Nebilonga", engari e taea te mahi i te reira i muri i anake te fariiraa i te tohutohu o te rata haere.

rahunga Heart Ko te puka ma'i

Tuatahi he horopeta iti o medicament, te rata āta whakanuia ana, homai nga āhuatanga o te manawanui. Hoki te maimoatanga o ngā puka whakapeka o "Nebilong" Ko e kore e tika ana, i roto i ngā take pērā, kua whakamahia ētahi atu taero. Ko te tikanga tuatahi whakaritea ki 1.25 mg o tarukino mō te whakamahi kotahi rā, i muri i 1-2 wiki kia nui haere te horopeta ki te 5 mg, a muri mai - ki runga ki te 10 mg. E kore e te horopeta rā nui 10 mg medicament "Nebilong". Tohutohu mō te whakamahi whakaatu e i te wāhanga tuatahi o te therapy te manawanui mahue i raro i kitea mō te rua haora i muri i ingestion o te papa, kia meatia ki ia tikanga horopeta te whakanui ake. Ka taea te heke ano horopeta nui ake ki te vai te hiahia.

Ki te tohu kore ngakau puta atu ātete korerotia manawanui ranei ki nga wae tarukino i kitea, whakaiti i te horopeta o te tarukino hua tona Tuhinga ranei. Tikanga, hohoro kore ngakau, puka ma'i o "Nebilongom" tukinotia. A, no te hāngai therapy i whakakore taua tikanga, te whakakāhoretanga o te tarukino ki pōturi, koutou e taea e kore mahi i tenei mahi koi, no te mea kia kino ake ngaa ai te raruraru. Ki te whakakore koe te tarukino kia whakaiti ia wiki te horopeta i te hawhe. Hoki tango i te pire whakarato "Nebilong AM" ā-ako hoki etahi here.

here:

• iti hoki tākihi. Tuatahi, mo te therapy whakamahi 2.5 mg o te raau taero ia ra, e taea te nui haere i muri i te horopeta, engari kore e nui te reira 5 mg.
• tau Tawhito. E kore ai te horopeta tuatahi nui 2.5 mg ki te tika, e whakaarahia ai ki te 5 mg. I muri i te 65 tau, e rapu tirohanga auau o (katoa e wha ki te rima nga marama kotahi) te whatukuhu.
• Hapūtanga. kia whakawhanake te hou etahi mate, ngā enei pāpāngia romahā, suka, hypotension, bradycardia, wahine kia hapu whakaritea te tarukino te rawa uaua. Ki te whakamahia e te wahine hapu e hiahiatia ana "Nebilong" tona whakakorenga te hoki 48-72 haora i mua i te tuku. Ki te kore e taea tenei, kia kitea te hou mō te 48-72 haora.

contraindications

"Nebilong H" opani ako ā-ringa te whakamahi i roto i te wā e whai ake nei:

• Tau iti iho i te 18 tau;
• hypersensitivity ki nga wae tarukino;
• bronchospasm, huangō (hītori);
• pheochromocytoma, e kore nei e i tukinotia i mua;
• acidosis pūkoro;
• pakeke puta mate ate, kore ate;
• hypotension i roto i te mau taata nei pēhanga o 90 mm HG iti ranei systolic. Tuhinga.;
• AV-poraka (māka ahau, III), bradycardia, haere tahi nei i auau ngakau ōrite ki te 60 bpm. ia meneti;
• i roto i te whanautanga tamariki, uma-kai;
• whakapeka kore ngakau hanga;
• raruraru ki te tohanga piringa, ki expressiveness oraora;
• ru cardiogenic, he huru i roto i te mea e tika ana ki te whakamahi i taero isotropic;
• syndrome, haere tahi pakohu mate.

hiahiatia tūpato te ka meinga te tarukino ki te tūroro ki te tikanga:

• mate huka;
• psoriasis (hītori);
• Prinzmetal angina.

pānga taha

I roto i te maimoatanga tikanga "Nebilong" ako ā-, arotake mea te tūponotanga o te takanga o etahi pānga taha, e kua whakakitea i roto i te mahi o te Cardiovascular, kūnatu me ngā pūnaha io. I roto i te tahi atu maumaui - bronchoconstriction tauhohenga e pa i te huru kiri.

Ara

"Nebilong" kia whakanuia te tūtohutanga ki allergens, e fakamanamanai te whanaketanga o nui tauhohenga anaphylactic.

e kore e maimoatanga Drug pā te taumata o te kūhuka i roto i te tinana i roto i te aroaro o te mate huka, engari tūroro i roto i tenei rōpū i ki te tono i te rongoā ki te tūpato. Ka rite ki i roto i te mate huka, me te i roto i te hyperthyroidism raau kia huna kanohi tohu o tachycardia, he reira atu korerotia e tika ana ki te withdrawal ohorere o te papa.

Ki te tūroro ki ngā raruraru i roto i te pūnaha romahā whakamahia te whakamōhio "Nebilong" ā-ako e pā ana ki te tūponotanga o te taonga constriction o nga Airways i COPD. kia takina te taea o te whakakotahi i te tarukino ki ētahi atu taero ki tō tākuta.

"Nebilong" pānga te kaha ki te pei i te waka, e taea arahi ki ngenge me te whanoke.

analogs

Ko taea ki te whakakapi tarukino e kore e tukua te whakamahi o te tarukino "Nebilong" ako ā-ringa. analogues Drug ngā "Nebilet", "Binelol". Na roto i te whakakapi ngā ano "Nebikor" me "Nebivator".

Reviews

Ka rite ki nga arotake, he whai hua te tarukino, i te whakamahia tika. He mea nui ki te whakamahi i te rongoā, me te whai ngā taunakitanga o tākuta katoa. whakaritea te medicament te ki te contraindications me ngā āhuatanga o te manawanui, hua i roto i te pānga pai. kihai taua maimoatanga i arahi ki te whanaketanga o ngā pānga taha, e hiahia ana koe ki te aroturuki tonu te huru o te manawanui.