Prothrombin taupū, auau, me te uara

Prothrombin taupū, te tere o te mea rite ki te 95-105%, - ko tetahi o nga tohu characterizing upoo- toto. upoo- toto - he tukanga rawa matatini kawea e te roto i ki te whai wāhitanga o te Niniiraa o pūmua motuhake i huaina āhuatanga coagulation. He taea te faaitoitoraa o tenei tukanga i roto i te rua ara - roto, o waho.

Reira faaite taupū prothrombin te faaitoitoraa o coagulation mā te ara, ēhara. Ko reira e whai ake: i roto i te ofatiraa o te tapatahi o te kopa (patunga) tohaina te pera-ka karanga thromboplastin kikokiko, he pūmua motuhake kitea i roto i te kopa tinana katoa. pāngia e te reira i te tauhohenga Niniiraa e tomo atu āhuatanga upoo- (V, VII, ko X, II, ahau), ä whakahohe tahi i te tahi. I te pae hopea, i hanga te katinga toto te ka mutu toto.

He aha e te taupū prothrombin

āhuatanga upoo- e hanga e i roto i te ate. O enei, he huaora K-ti'aturi II, V, X. Ki te kore o te huaora fakahohaasi ratou kōtuitanga te. Fakatatau ki ai, i reira he maumaui o hemostasis. E matau te taupū prothrombin, i te mea auau mōhiotia, koutou tākuta kia:

1. Mahi Auau petipeti II, V, VII me X āhuatanga tuli hoki
2. Ko te rahi o tenei tohu ki te whakawa i te mahi o te ate
3. I te waiwai o te huaora K
4. Ko te āhua whānui o te pūnaha toto coagulation
5. E ai ki tenei tohu, ka taea e koe te aroturuki i te whai huatanga o te therapy anticoagulant.

Ka rite ki whakaritea e te taupū prothrombin

takoto Prothrombin taupū e i roto i te capillary toto venous ranei. I roto i te take tuarua tangohia nohopuku toto e ki te ipuipu ki te anticoagulant i roto i te ōwehenga o 9: 1. Ka rite ki te whakamahia te konutai citrate anticoagulant. I roto i te taiwhanga, te toto centrifuged te. Kei te whakamahia te wē hua mo te faaotiraa o te wā prothrombin (PT). Ko Norm MF i roto i te whānui i te 12 ki te 20 hēkona, i runga i te mahi o te thromboplastin whakamahia i roto i te akoranga o te tauhohenga i roto i te taiwhanga rānei.

E matau PT o te manawanui, ka taea e koe te tatau i te PI, arā, prothrombin taupū, i te mea te täkupu i roto i ngā taiwhanga rerekē e taea hoki e te bit rerekē. Ko rite ki te ōwehenga PX ia tangata hauora ki te manawanui PV, whakanuia e 100:

PI = PV hauora. / SA mate. X 100 (noa 95-105%)

Ko te hiranga haumanu o PI

I teitei coagulation PT ranei prothrombin i mutua nei täkupu o 12 ki te 20 hēkona, me piki PI. Ka taea e tenei i roto i hapūtanga, ki te wharanga nui ina tae mai te toto i te rota o te kiko thromboplastin.

Engari, MF piki me te heke ki te hekenga i roto i PI upoo-, pērā i roto i te take o te hē congenital o āhuatanga upoo-, ki te mate ate kino, ki te hē o te huaora K (e ai puta i roto i te cholestasis, dysbacteriosis, ia mutu te mahi punuatuna). heke PI ki pūwētoto iti te hauātanga mahi ranei, ki te syndrome hoki, i roto i te aroaro o te matū e tautāwhi i upoo-.

He aha te mea INR

Maimoatanga o anticoagulants autaki fakanatula whakaiti prothrombin taupū. Ka taea e tōna täkupu e kia ona ake i roto i nga taiwhanga. Na reira, i roto i te tikanga ki te taea ki te whakarite i te hua whakamātautau whiwhi i roto i taiwhanga rerekē, i whakaurua ai he whakamātautau paerewa pērā i INR. Tenei taupū tātaitanga. Kei te takoto te reira i hāngai i runga i te ōwehenga o te wa prothrombin o te manawanui, te uara noa MF me tohu thromboplastin tūtohutanga taupū (ISI).

INR = (PT b th / MF rate) i roto i te tohu o ISI

I roto i te tangata hauora te INR i roto i te whānuitanga 0 8-1,2.

whakamahia ana tēnei tohu i roto i te aroturuki i te tōtika o anticoagulants mahi. I roto i te maimoatanga o te anticoagulant ka heke coagulation te (hei tauira i muri i te pokanga ngakau) kia nui haere INR ki 2-3. Ki te whakanui ake i INR upoo- iti te. Ko te ōwehenga i waenganui i te PI me te INR he taua e nui haere te hekenga i roto i te taupū PI INR.