Urea i roto i te toto. Te whakatairanga me te tukupu te ihirangi

synthesized Urea te i roto i te tukanga o te neutralization o haukini i roto i te ate. Kei te hanga e te reira i roto i te tauhohe o te waikawa amino deamination. pā ana tiomimi ki pūhui o iti taimaha rāpoi. He te kaha ki te noa tika i roto i te kiriuhi pūtau o erythrocytes me okana parenchymal. tiomimi i te filtration toto puta i roto i te glomeruli. Otiia i te wa taua kawea ona reabsorption tino (hāngū) te roto i te tubules.

aro tiomimi toto rite ki te ariā o te auau filtration glomerular me perfusion tākihi.

Tenei pūhui he tāoke iti, engari te tāoke o pärönaki guanidine riro whakaemi katote pāhare pāporo ki reira. Ko te hoki Urea he taonga kaha osmotically, na ka te tohua reira haaputuputuraa o edema i nga kopa o whekau parenchymatous, myocardium, io pokapū, kiko subcutaneous.

Kei te maha toto Urea (tona kukū i roto i te wē) whakaaro he tohu o te pūrere glomerular mahi tākihi. Heoi, whakamana te whakatau tata tika atu i runga i te ihirangi o te creatinine.

Te whakanui ake i te hanganga Urea kitea i roto i te whakamahi o rahi o āhua catabolic pūmua, me te absorption o te pūmua, me te amino waikawa i muri toto pekitīlia. Te whakanui ake i tona kukū kitea i roto i te maroketanga tika ki nui haere reabsorption hāngū i roto i tubules tākihi.

Urea iti toto (wē) i raro i te waihanga whakararuraru, mahi ate, me te he horomanga pūmua iti. Ko te ihirangi o te pūhui i roto i te serum kia whakanui i tika ki te fariiraa o te raau taero takitahi. Ēnei rongoā ngā phenylbutazone, steroids anabolic, dopegit, tāpiringa rino, aldomet, taero nephrotoxic.

Tuhinga o Urea i roto i te toto kia tohu mate ate (kakā, i tae atu viral, cirrhosis, pukupuku). Ko e tika ana ki te meka i tenei tinana i reira ko te hanganga o te pūhui taketake tenei. A, no te puta ofatiraa me ate mate tiomimi production. I roto i tenei take, e taea e kore tonu te mārama te tohu o te mate. kia whakaaro te tohu matua rite ngoikore, mate o hiahia, rohirohi, jaundice, te paowa kawa, hūhi i roto i te hypochondrium tika.

I roto i mate o te pūnaha kūnatu, haere tahi i te malabsorption o waikawa amino hanga ake pūmua i roto i te wā postoperative e pā ana ki ngā wawaotanga mō ngā mate intestinal, pancreatitis ma'i, mau ma'i pirinoa hoki tuhia heke Urea i roto i te toto. Me whakahaua maimoatanga o tenei i whakatutuki i te mate whāriki. Ka rite ki te tikanga, i muri i te pae whakakahoretia o te mate me ngā whakamātautau tonu o.

Me kï reira e takoto te ihirangi o te pūhui i roto i te mimi e tona kukū i roto i te toto. e hoki ki te pūkete te nui o filtration i roto i nga whatukuhu.

Urea toto noa ko 2,8-8,3 mmol / l. Tikanga, ka te tukanga noa o te pūmua pākia, e uaua kitea ona tirotiro mo neke atu i te 6 mmol / l. I roto i te take i reira ko te iti kai i roto i te pūmua, heke te kukū pūhui te ki te 2 mmol / rita.

Nui haere Urea i roto i te toto (te nuinga o te kukū ko e rave rahi taime te tohu noa o runga), te nuinga o tahi i te haurangi kino, ka karanga uremia. tuhia te reira i te huru rite i runga i te whakamārama o te mate e whai ake nei:

- tākihi rahunga puka whakapeka;

- pyelonephritis, glomerulonephritis;

- anuria (ngaro o mimi syndrome, e kore e he tangata defecate);

- mate huka;

- te pukupuku ranei concrements i roto i te taiawa mimi awa mimi ranei;

- weranga;

- peritonitis;

- ru;

- phenol paihana, tai mēkuri, chloroform;

- Gastro-intestinal toto.