"Cymbalta": tohutohu mō te whakamahi. Reviews, utu, tohu

I teie mahana, e korero matou ki a koutou e te mea he tarukino "Cymbalta." Ka tohutohu hoki te whakamahi o te raau taero, tona hanganga, ngā pānga taha, me pānuitanga kia whakaahuatia i raro nei. Hoki i te tuhinga tukuna, ka ako koe e pā ana ki te puka i roto i te mea e wātea ana te tarukino, te nui o te utu i te reira, ahakoa kua ia he contraindication me pehea ki te tono tika reira.

Puka tuku

I roto i te aha puka e taea te hoko i te reira i te tarukino "Cymbalta" ako 'i he ngaahi roto i te mōkihi? I tēnei wā kei te anake tukua te raau taero i roto i te puka o capsules enteric. Ia o e kei nga pire, e whai he tae ma ma grayish ranei.

te raau taero

He aha wāhanga ngā tarukino "Cymbalta?" kī Tohutohu mō te whakamahi o capsules e ratou huānga kaha matua ko te duloxetine taonga. Me mahara hoki käore te reira e te hanganga o te medicament whakaaro me ngā matū atu rite sucrose, hypromellose, talc, succinate, colorant ma, tāpia hypromellose, Titanium hāorarua, triethyl citrate, gelatin, konutai lauryl pūkawa me kōwhai ngarahu rino waikura.

kia roto i capsules 60 me 30 tarukino mg. E Kikī ratou i roto i te opupu o 14 ranei 7 capsules. I roto i te kotahi mōkihi kātene taea e 1, 2 ranei 6 opupu.

āhuatanga pharmacological o te tarukino

He aha te mea te taonga hohe pērā i duloxetine? kī Tohutohu mō te whakamahi o capsules rongoa e te taua mahi tarukino ki huānga mea he rawa raau pai. Ko reira he inhibitor o te reuptake o norepinephrine me serotonin. Ia ngonge inhibits dopamine häpai me kahore pakuwha ki dopamine, histamine, me receptors adrenergic holino-.

Nahea Duloxetine? Kei Guide te mōhiohio e whai ake nei i runga i tenei kaupapa: ko te parau tumu o te mahi o te taonga, ko te ki te tautāwhi i reuptake o norepinephrine me serotonin. Ka rite ki te hua, tino whakanuia ana noradrenergic me serotonergic neurotransmission i roto i te pūnaha io. Me mahara hoki käore te reira e duloxetine hohoro pehi mamae.

Pharmacokinetics o te tarukino

Formulations o te korekore o te "Cymbalta" whenumi i te wahi gastrointestinal, tīmata absorption he torutoru haora i muri i whakahaere. tutuki ana te kukū mōrahi te i muri i te 6 haora. e kore e fariiraa tukutahi o kai pā te kukū me te faarahi te wa ki te whakatutuki i te 6 ki te 10 haora. Tohunga mea e reira autaki whakaiti te whānuitanga o te absorption (11%).

Ka herea e o tarukino ki pūmua wē he tiketike nui me tae atu i te 90%.

Ko te hawhe ora o te tarukino ko 12 haora. I te wa ano e haere ia i roto i roto i te mimi rite metabolites.

E ai ki ngā akoranga, i reira he rerekētanga i waenganui i nga tukanga pharmacokinetic e puta i roto i nga wahine, me te tangata. Ko te kupu, ko te whakawātea toharite o te whakauru kaha i raro i te takoto ataahua. Heoi, e kore te mea e tika ana horopeta whakarerekētanga.

Me mahara hoki käore te reira e whakapumautia nga rerekētanga i waenganui i te tukanga pharmacokinetic e puta i roto i nga tūroro paari me waenganui-koroheke i roto i te tūhuratanga. whakakitea te reira e te hawhe-ora o te tarukino ko teitei i roto i te paari i te iwi taitamariki. e kore te No whakatikatikanga inenga e hiahiatia ana rānei.

I roto i te tūroro ki te iti hoki tākihi ma'i i roto i te atamira kāpeka, e te hunga i runga i tātari, te kukū o te mahi, me te AUC o piki duloxetine i rite 2 nga wa. Ko te mea i tūtohutia aha ki te whakaaro i te ahua paitanga o te whakaiti i te inenga o te tarukino i roto i te tūroro ki te waimaerotanga nui o te mahi tākihi.

Tūroro ki tohumate o te kore ate e taea pōturi pākia me whakakorenga hawhe-ora o duloxetine.

Tuhinga mo te whakamahi o moni

A, no te kaitūtohu "Cymbalta?" Tohutohu mō te whakamahi ngā te rārangi e whai ake nei o pānuitanga:

• mate huka āhua neuropathy mamae;
• āhua whārua me fakalotofo'í;
• whakararuraru, manukanuka whānui;
• mamae ma'i syndrome musculoskeletal, tae atu te hunga meinga e fibromyalgia me te osteoarthritis.

Contraindications ki te whakamahi o moni

A, no te kore e taea e koe te tango i rongoa "Cymbalta?" Tohutohu mō te whakamahi ngā te rārangi e whai ake nei o contraindications:

• tono tukutahi o inhibitors puai o isoenzyme CYP1A2 (hei tauira, enoxacin, ciprofloxacin fluvoxamine ranei);
• tūtohutanga nui ake ki te manawanui tikanga wāhanga;
• tamariki i raro i te 18 tau o te tau;
• he fariiraa rangitahi kau ki inhibitors Mao;
• Ko takawhita matua whakakeke;
• papahewa katinga uncompensated;
• nui täkihi ma'i (ki CC iti ake i te 30 ml / min);
• hē isomaltase ranei saccharase, kūhuka-galactose malabsorption me te huahuka ātete;
• mate ate e kua haere tahi i te iti hoki ate.

A, no te kia whakamahia ki te tūpato tarukino

kia whakamahia te reira i āta mea tarukino i roto i te mate pourua me mania, mōrea haehae hoki whakaeke koki-katinga papahewa. Hoki, me te tiaki kia mau takawhita ka ocular, whakaaro suicidal, hyponatremia, ate me te tākihi.

Drug "Cymbalta": tohutohu mō te whakamahi

Ko te utu o tenei hua he tiketike rawa. Heoi, e kore te mea i raro ki tetahi feaa tona whai huatanga.

i whakaritea rongoā Vauvauhia te anake hoki whakahaere-waha. Me horomia nga capsules katoa kahore kuru ngaungau ratou ranei. Me kï reira e i roto i kore e taea te tāpiri i tetahi take ki te tarukino kai ranei uru reira ki tetahi fluids, mai i taua mahi i taea e ngāwari kino te paninga enteric.

kia tangohia formulations o te whārua i te inenga tuatahi o 60 mg kotahi te ra. I roto i te tikanga ki te whakatutuki i ngā hua pai i roto i te tahi mau tūroro ki te whakapiki ake i te nui mea ki te horopeta mōrahi o 120 mg rua he ra.

Tūroro pāngia ki te mate täkihi ma'i, e puta i roto i te wā kāpeka, te inenga tuatahi o te medicament ko 30 mg kotahi te ra. Ki te whai tūroro ate arā, tūtohutia te nui tohua o te tarukino te ki raro whakaiti te tini o te fariiraa ranei.

Me mahara hoki käore te reira e ki te karo i withdrawal ia'na te fariiraa i medicament. Ko te nui o te tarukino e tika ana ki te whakaiti māmālie mo 1-2 wiki. Ki te tenei whakamārama, i reira he tohu korerotia o te syndrome, e tūtohu ana ki te haere tonu maimoatanga i roto i te inenga whakaritea. I muri, kia haere tonu te tākuta ki te whakaiti i te horopeta, engari atu āta.

take o te tuwhena rawa

He aha tohunga te mea e pā ana ki te take tarukino tuwhena rawa, "Cymbalta?" Reviews o taote i roto i ngā mōhiohio e pera raraunga e wātea ana ki a ratou. Ki te rā, i reira he take o te tuwhena rawa i ingestion o te tarukino i roto i te moni ki runga ki te 3000 mg, a ka te ngā reira ki ētahi atu āpiha. Ratau, whakaritea me kotahi te mate.

Tohu o te tuwhena rawa ranei taratahi ngā ngā te huru e whai ake nei: haehae clonic, somnolence, ruaki, pōroa, serotonin syndrome me tachycardia. Ko te rangahau preclinical (ngā i runga i te kararehe), te tohu matua o te tāoke e pā ana ki medicament tangohanga whakakeke, he disorders o nga pūnaha io, me te kūnatunga pokapū. Hoki, kia puta tūroro faaati, ataxia, haehae clonic, ruaki me te mate o te hiahia.

Aha ki te mahi i roto i te take o te tuwhena rawa? Ki te whanaketanga o te serotonin syndrome kia tonu kawea atu cyproheptadine therapy fakatonutonu, me te te tikanga e whakamahia ana ki te haerenga, te pāmahana te tinana o te manawanui.

hiahiatia ana te manawanui e ki te whakarato i te hau hou. kia aroturuki hoki e koe te mahi o te ngakau, me te aroturuki tohu faufaa. tenei katoa kia mahi i roto i te taha ki te tautoko pupuri me te maimoatanga symptomatic.

Ki te muri kihai i whakahaere o te tarukino roa, he mea e tika ana ki te horoi i te kopu. Hoki, i roto i te tikanga ki te whakawhāiti i te rōpū o te rongoā ui te manawanui e ki te inu waro whakahohe.

pānga taha

E taea te pānga kino i runga i te hauora tangata o te fariiraa mea rongoā? A feruri i te pānga taha o raau taero raau i roto i te taipitopito atu:

• Tino maha (i roto i te 10% o te wā) i roto i te rangahau haumanu, tūroro i te āhua e whai ake nei: whanoke, pāhoahoa, mangai maroke, ohoroa, ohoroa, whakapairuaki, momoe me te kōroke.
• tapeke Iti (1 ki te 10% o ngā take) tūroro i kitea te Makere, korere, kite te peroo, ruaki, sweating, faaati, nui haere anorgasmia, heke hiahia, mate o libido, mate taimaha, rohirohi, erectile pōrearea, ka whakaroa hoki ranei ejaculation rerekē.

E kore e taea e tatou te mea e penei pānga taha rite te whanoke (i ētahi wā pāhoahoa me whakapairuaki), maha kite ki whakakorenga ohorere o te medicament. E te ara, i roto i tūroro ki mamae puka neuropathy huka kia wheako he hua i roto i te kūhuka toto i runga i te puku kau.

Reviews o medicament

E ai ki ngā mātanga, me ngā tūroro tino akakoromaki rongoā whakaaro ki te mahi. Ki runga ki te fariiraa i faaore te reira i te mate manukanuka, me te whakatairanga i te ngaro o āhua fakalotofo'í. I tua atu, relieves kaha pai medicament syndromes mamae i roto i te pūnaha musculoskeletal.

Ngā pāhekoheko ki ētahi atu tikanga

He reira taea ki te tahi-whakahaere o te tahi atu raau taero ki rongoā "Cymbalta?" tohunga te āheinga mea e te tikanga mea ko te pānga tika i runga i te whai huatanga o te tahi mau rongoā.

Heoi, i reira ko te mōrea o te serotonin syndrome, duloxetine ki te whakamahia i roto i ngā ki MAOIs.

No te mea kei te whai wāhi CYP1A2 isoenzyme i te pākia o "teuteu Cymbalta ', ka taea e ratou te whakamahi tukutahi arahi ki nui haere ngä nohanga o te muri.

Ehara i tūtohutia hoki medicament mea tahi ki ētahi atu taero e pā te pūnaha io pokapū. Hoki i roto i tona whakauru kore e inu waipiro.

I te tahi taime, i te whakamahi o SSRI me māngai serotonergic i roto i tūroro kitea serotonin syndrome. Na reira, me faaohipa koe tūpato tino ka whakamahi i tenei tarukino ki pōuritanga serotonergic.

Nā ki te meka i reira he he nui haere tūpono o te toto e kore e whakamahi i rua duloxetine me anticoagulants (antithrombotics).

Ū me te hapū

Ka taea e te whakamahi ahau i te tarukino "Cymbalta", te utu o e ka e te aroaro i runga i, i roto i te hapūtanga? Nā ki te kore o rawaka ngā mōhiohio, kia te whakamahi o te taonga duloxetine roto i te hapūtanga kia whakahaerea te rongoā anake, ki te te painga ki te whaea expectant he nui ki runga ake i te mōrea mō te tamaiti.

Me mahara hoki käore te reira e tūroro tango tenei kaihoko kia kia mohio ki te whakamōhio i tō tākuta e pā ana ki te takanga whakamahere i te hapū ranei.

Kua whakaaturia Studies e wahine tango pōuritanga i roto i te kāwanatanga, ina koa i roto i nga wāhanga i muri mai, nui faarahi te mōrea o te tamau takawhita pūkahukahu o te tamariki whanau hou. I roto i tenei take, te syndrome hoki pinepine kitea i roto i ngā tamariki i roto i te take o te mutu ohorere te whakamahi i te whaea duloxetine heke mai i te wā mutunga o te hapūtanga. Te nuinga o nga tohu o tenei huru i kitea i roto i te tuku ranei i nga ra tuatahi i muri.

No te mea taea ki te tomo ki roto ki te waiu, uma duloxetine ko, e kore te mea te reira e minaminatia ki te ū tō pēpi i roto i therapy. Kore, ka kia te kukū o te taonga i roto i te kukune i te nui o 0,14% o te kukū i roto i te whaea.

arata'iraa Motuhake i runga i te whakamahi o te raau taero

Mā te tautapa i te tarukino ki tona manawanui "Cymbalta", takoto te tākuta kei te ki whakamōhio ia e hua'tu opani te whakauru kotahi-wā o te kaihoko ki inhibitors Mao. Kore, ka taea e whakawehi reira pōauautanga mate, me te nui o te tūāhuruiti, myoclonus me te whakawhiti excitation whakahuatia ki te pōroa.

Me mahara hoki käore te reira e te tapui whiwhi mea rongoā mō te rua wiki i muri i maimoatanga inhibitors Mao.

E ai ki ngā akoranga, i roto i tūroro ki āhua härukiruki ka whakamahi i te tahi atu raau taero e pā te pūnaha io, i roto i te taha ki te tikanga "Cymbalta" kia kē mate ngā.

Nā ki te meka i roto i āhua fakalotofo'í reira ko te tūponotanga ka o ngā nganatanga whakamomori, kia rawa aroturuki tūroro no ki te rōpū mōrearea.

Whakaae o te tarukino e taea e rawa ngāwari ki te meinga te momoe. Na reira, tūroro e tangohia tenei tarukino, kia tangohia e koe te tiaki anō ka peia a ka mahi ki mīhini pokarekarenga kino.

Utu me analogues o te tarukino

Kia pehea te nui Ko te "Cymbalta" capsules enteric? kia rerekē ratou utu. Tei te reira i runga i te kaiwhakanao me te tawhē mekameka rongoā. Heoi, kia tuhia te reira e runga toharite, utu te raau e pā ana ki 1.050 moni Russian (30 mg, 14 nga wahi). Ki te hiahia koe ki te hoko i te rongoā i roto i te moni kotahi, engari i te inenga o 60 mg, na ka whai koe ki te utu e pā ana ki 1150 moni.

Na e matau ana koutou ki te nui o he duloxetine. kia whakanui i tōna utu heke i runga i etahi āhuatanga ranei. I tēnei wā, ka karanga te hoko ko e kore ko te tarukino tetahi uauatanga. Heoi, ka taea e te hoko e koe i te reira anake i te whakahaunga.

Ko te aha, ki te koutou mo etahi take kihai i i ahei ki te hoko i te "Cymbalta" capsules rongoa? E wātea ana Analogs o tenei tarukino i roto i tata rongoā katoa. Ahakoa te rironga ka rapua e hoki te aroaro o te whakahaunga i te tākuta.

Ka taea te whakakapi i te tarukino "Cymbalta?" I roto i ona hoa e hiahia ana ki te whakanui i rawa te rongoa e whai ake nei:

• "Intro";
• "Azafen" (papa);
• "Duloxetine Canon" (Enteric capsules);
• "Venlafaxine Sandoz";
• "Alvent";
• "Mirtazapine Canon";
• "Eprobemide" (otinga i roto i / me te / m);
• "Wellbutrin";
• "Eprobemide" papa;
• "Agomelatine";
• "Neyroplant";
• "Velafaks";
• "Calixtus";
• "Venlaksor";
• "Vensuert";
• "Dapfiks";
• "Venlift FFkm";
• "Despres ';
• "Ia faataere Efevelon";
• "Doppelgerts Nervotonik" rite te elixir;
• "Inkazana";
• "Efevelon";
• "Coaxil";
• "Esprital";
• "Lerivon";
• "Trittiko";
• "Normazidol";
• "Mirzaten";
• "Tetrindol";
• "Mirtazonal";
• "Remeron";
• "Mirtalan";
• "Pirazidol";
• "Negrustin";
• "Nyuvelong";
• "Noksibel".

Ko te tikanga o te rokiroki me te papa-ora

He aha te mea te ora papa o te tarukino "Cymbalta?" E ai ki nga tohutohu, me te rā i runga i te tākai, e kore e tenei taputapu e tangohia mo te wā o nga tau e toru. I roto i tenei take kia rongoatia reira i roto i te wahi pouri te wahi e kore e te pāmahana nui 20 nekehanga.