Ko te tarukino "Pentas": tohutohu mō te whakamahi, analogs me arotake

I roto i te horopeta o rongoā tikanga "Pentas"? Tohutohu mō te whakamahi, me arotake o te tarukino whakaahuatia i raro nei. i roto i te tuhinga rauemi hoki whakarato mōhiohio e pā ana te puka o tuku o te tarukino me ona āhuatanga.

Te hanganga, medicament āhua

He maha ngā momo o te tuku whakaaro rongoā. tapaea tatou ratou i teie nei.

Te faaineineraa "pentasil" - Papa (500 mg, 100 mg) mahi auroa. He ma ki te urukehu grayish, me te maha pāti o parauri marama, te āhua a tawhio tika, ki Valium, Heretua me inscriptions i runga i ngā taha e rua ratou.

Ko te huānga kaha o tenei rongoā ko mesalazine. Ano ko nga tikanga i roto i te puka o te paruparu kai povidone, ethylcellulose, stearate konupora, talc, me microcrystalline cellulose.

I roto i te hoko o te tarukino "Pentas" (papa), he whakaahua o i te aroaro o te i roto i te tuhinga tukua te i roto i mōkihi namunamu e te hunga i roto i te kātene pepa.

Me mahara hoki käore te reira e taea te hokona te medicament kaupapa i roto i te puka o suppositories, granules roa-tuku me te whakatārewatanga rectal.

rongoa Pūtaiao

He aha te mea te rongoa hoki "Pentas"? Tohutohu mō te whakamahi kī e ki tenei kaihoko ki te mahi anti-inflammatory me whakamahia hamani colitis ulcerative me te mate o Crohn.

āhuatanga Anti-inflammatory o te tarukino whakakitea anake hoki te whakamahi rohe. meinga ana tēnei mahi e ariā o leukotrienes me prostaglandins, rite pai rite te inhibition o mahi lipoxygenase (neutrophil). I tua atu, e taea ki te faataere i te secretion o immunoglobulin i lymphocytes me ki te tautāwhi degranulation, me phagocytosis o neutrophil hekenga te taputapu, ko te.

āpiha Rawa gastrointestinal

Ko te medicament "pentasil" (te papa), te hanganga o nei i te aroaro i runga, korerotia whakaatu mahi antibacterial ki etahi cocci me Escherichia coli. Ano, te mea he pānga antioxidant tika ki tona kaha ki te here i te taonga kaha ki Radicals free (hāora), me te whakangaro ia ratou.

whakamahi tika o tenei taputapu nui te whakaiti i te tūponotanga o te matahoki i roto i te mate o Crohn, tae atu ki ngā iwi ki te ileitis (ki te roanga mate roa).

Ko te parau tumu o te mahi o ngā whakaurunga hauora

Nahea te tarukino "Pentas"? Tohutohu i runga i te tono i whakapuakina ai e te pānga haumanu o te tarukino ko tonu i muri i wā mesalazine whakapā ki te mucosa intestinal.

I muri tango papa-waha te tikanga tonu saietí i microgranules e mahi rite puka motuhake, me te paturuhia tuku taonga hohe - mesalazine. E whakarato ana tēnei i te tarukino waiwaiā hoki i waenganui i 12 ki te tōu i ngā uara pH katoa.

tikanga Pharmacokinetics

Nahea te absorption o te tarukino "Pentas"? Tohutohu mō te whakamahi o ngā pūrongo e microgranules o papa nofo 12 tae te duodenum i roto i te 60 meneti tuatahi.

Tata 30-50% o te inenga whenumi o te raau taero i roto i te whēkau iti. Communication mesalazine ki pūmua wē he 43%, me te waikawa N-acetyl-rima-aminosalicylic - 73-85%.

Mesalazine me ona pärönaki kore e ô i te BBB. E whakakitea āhuatanga tarukino Tapeke anake ka whakamahi i pota teitei (e pā ana ki 1500 mg ia ra).

kitea Acetylation mesalazine te i roto i te mucosa intestinal me ate. I ahu mai tēnei taonga te i te mimi, uma waiu me feces.

Tuhinga mō te whakamahi o ngā rongoā

I roto i ētahi wā, kia tohua ai rongoā "Pentas" (papa)? tohunga te āheinga mea e te raau mahi pai, no te:

• colitis ulcerative;
• mate o Crohn.

Ūhia ki te whakamahi o te raau taero

I raro i te mea e kore e taea e tikanga te whakamahi i te taputapu pērā i "Pentas"? Tohutohu (papa, me ētahi atu momo o taero i te taua contraindications) ta te rāhui e whai ake nei:

• hemorrhagic diathesis;
• mate toto;
• hohipera;
• Kūnatunga mariao tuleki;
• te 2-5 wiki whakamutunga o te haputanga;
• kore o te kūhuka-6-Phosphate dehydrogenase;
• te tau o rua;
• nui täkihi;
• hypersensitivity ki āpiha Matū;
• nui iti hoki ate.

kia whakaaro tiaki Special he tarukino whakamahia i roto i te huatū tuatahi o hapūtanga, me te ate me te tākihi kore.

Medicament "Pentas": tohutohu mō te whakamahi

Te tohu i te puka inenga o te raau taero tei runga i te localization o te tukanga pathologic matua, me te te roa o pāpaka intestinal.

Suppositories "pentasil" me te whakatārewatanga i whakahaere i nga puka distal o te mate (proctosigmoiditis). I te wa ano i whakamahia e toru kānara i te ra o te 500 mg.

Me pēhea te ki te whakahau rongoā-waha "Pentas" (papa)? kī Tohutohu mō te whakamahi e te tūtohutia tenei momo o te tarukino anake mo momo noa o te mate. Hoki te ārai o relapses i roto i te mate o Crohn tono te medicament te wha nga wa he ra (1 g mesalazine). No nia i te ārai o te matahoki o UC, i roto i tenei take, whakaritea te raau e toru ngā wā i te ra 500 mg.

I te exacerbation o te akoranga mate o te maimoatanga e muri hoki 8-12 wiki. I te wa ano e tango 400-800 mg o te tarukino (toru nga wa ia) i tenei ra.

I roto i te mate nui kia whakapiki ake i te inenga rā o 3-4 g

Papa "pentasil" kia pai kia tangohia tika i muri i te kai, ka romia wai wai noa.

Hohenga i-pūāhua

I roto i ētahi wā, te tarukino i roto i te pātai ko te pānga taha e whai ake:

• stomatitis, faaati o wahi, mangai maroke, whanoke, whakapairuaki, huru tumatatenga;
• mate o te hiahia, ongo'i palpitations, tokopā, hāhā o te manawa i roto i ngā mahi tinana, ruaki;
• hematuria, korere syndrome, tachycardia, kakā, pouaka mamae;
• te whakanui ake whākōkī ate, rerekē te pēhanga toto, pancreatitis, polyneuropathy;
• crystalluria, tinnitus, proteinuria (pūmua papī), pāhoahoa migraine;
• oliguria, leukopenia, anuria (ngaro o urination), thrombocytopenia, hanganga syndrome nephrotic ;
• hypoprothrombinemia, agranulocytosis, eosinophilia, anemia.

Me mahara hoki käore te reira e taea te kitea te rōpū o tenei tarukino i roto i te manawanui: olisgospermiya, alopecia, photosensitivity, ngoikore i roto i wahi, syndrome lupus-rite, production iti o roimata inu, parotitis.

Tuwhena rawa o raau taero

Tuwhena rawa mo ki te tikanga ki te faaohipa nui ake sleepiness, whakapairuaki, gastralgia, ruaki me te ngoikore, puta noa i te tinana. Hei whakakore i enei tohu rapu lavage pekitīlia arä rite te pai kia rite ki te whakarite o laxatives rongoā me posindromnoy therapy.

taunekeneke tarukino

taea ki te pōturi te auau o te absorption o cyanocobalamin te medicament "pentasil" ko. faarahi hoki Mesalazine te tōtika o āpiha uricosuric (tae atu ki ngā blockers o secretion tubular).

kia mōhio hoki tatou e glucocorticosteroids piki tarukino kaha ulzerogennosti whakaiti i te pānga o te rifampicin me whakarei ake te tāoke o methotrexate puai pānga hypoglycemic i runga i pärönaki sulfonylurea, spironolactone, furosemide me sulfonamides.

mōhiohio tauwhāiti

I te whakauru o te horopeta kotahi o te mesalazine e tūtohu ana ki te tango i reira me ki te whai ake ranei i roto i te heke mai rawa tata. Ki te i ngaro i te reira i te torutoru pota, kia kōrero tonu koe i tō tākuta. Kei te rāhuitia te reira ki te mutu maimoatanga i runga i to ratou ake.

I te tahi taime kitea te papamuri o te āpiha pūrongo i roto i tūroro mimi poke me ngā arotahi whakapā i roto i te hue kōwhai-karaka.

I roto i te maimoatanga o te mesalazine titau te tirotiro hauora tamau i runga i te mahi o te pūnaha tākihi o te manawanui. Hoki, kia te tātaritanga o mimi o te manawanui me te toto wā (puta noa i te akoranga o te therapy, me te i muri i tona otinga).

nui haere te tūponotanga o te takanga o tauhohe kino i roto i te tūroro te fariiraa i tenei tarukino e i roto i te hunga e e "acetylators puhoi".

Ki te whanaketanga o te syndrome whakapeka o ātete ki te faaineineraa whakauru kaha "Pentas" hurihia tonu.

raau taero e rite me arotake kiritaki

E mōhio o te aha e taea te whakaaro ki te whakakapi i te rongoā ki a koutou? I runga i tenei me e koe te tākuta te haere. Ka rite ki te tikanga whānui, ki analogues o tenei taputapu ngā te raau taero e whai ake nei: "Mesakol", "Salozinal" "Salofalk", "Mezavant", "Mesalazin" "Asacol".

He aha te iwi e mea e pā ana ki tenei taputapu, kiritaki? E ai ki o ratou whakautu, ka mea medicament Ko te tarukino tino whai hua e taea te hokona i tetahi rongoā. titau Tūroro e mesalazine he pānui rawa pai iho i roto i te maimoatanga e kore anake, engari ano i roto i te ārai o te mate o Crohn me colitis ulcerative.