"Moxifloxacin": tohutohu mō te whakamahi, whakaahuatanga, hanganga

Ko te medicament "Moxifloxacin" pānga pharmacological o e ka e kōrero ake nei, e pā ana ki te rōpū o quinolones. Ko te taputapu he bactericidal, pānga antibacterial. Next, a aparau i tatou te mea te tikanga he rongoā "Moxifloxacin". Tohutohu mō te whakamahi, ka hoki analogues kia whakaaturia i roto i te tuhinga.

pānga

Pehea he kaihoko hohe "Moxifloxacin"? kia timata Whakaahuatanga o te tarukino ki te whakamārama o te huarahi o tona pānga i runga i te huakita. pānga bactericidal e pā ana tikanga ki te inhibition (pehanga) o kitakita IV topoisomerase me II. Tenei, i roto i te tahuri, arata'i ki raruraru i roto i te tukanga tukuruatanga o te tuhi, te biosynthesis DNA hanga pūtau koiora. Ka rite ki te hua, i reira mai to ratou whakangaromanga. whakaahua ana Medicament "Moxifloxacin" ā-ako rite te rongoā paturopi whānui.

ātete

I runga i te mahi antibacterial o taero "Moxifloxacin" e kore e pā te tikanga e whakapataritari te ātete ki tetracyclines, macrolides, aminoglycosides, cephalosporins me penicillins. Te reira i kore tohua pai me te pānga o te ripeka-resistance. Tae noa nei, e kore i take o wē pūmautanga tāutuhia. Drug resistance "Moxifloxacin" whakawhanake rawa āta e irakētanga maha.

whānui o te mahi

Tikanga "Moxifloxacin (ako ā-- tohu) pānga maha taumahatanga o Gram-pai, me te Gram-kino huakita, huakita waikawa-nohopuku, anaerobes, microorganisms mohiotia (mycoplasma, chlamydia, aha), a hoki huakita e te hunga ātete ki macrolide me beta-lactam taero rongoā paturopi .

momi

A, no te fariiraa i te absorption-waha o te tarukino "Moxifloxacin" tere, me te tata oti. bioavailability Absolute ka whakahaere pâmuhia me tono whekau - o te tikanga o 91%. A, no te whakahaere waha (50-1200 mg horopeta, 600 mg / ra mo 10 ra) pharmacokinetics rārangi o te tarukino. Ko te kukū mōrahi ki 400 mg kitea i muri i 0.5-4 haora. A, no te tono tukutahi ki te kai whakatutuki he hua i roto i te wā roa Cmax (e rua haora) me tona whakaiti i pā ana ki 16%. Roanga absorption kupu tonu tonu. Otiia, e kore e enei raraunga i te uara haumanu e taea te whakamahi o te tarukino "Moxifloxacin", ahakoa o te kai. I muri i te whaowhia rō-uaua kotahi o 400 mg mo te kukū haora mōrahi puta i te mutunga o te whaowhia.

tohatoha

I roto e toru nga ra o te tono tae te taurite. Ka herea e ki pūmua wē - e pā ana ki 45%. tuhipoka reira tohatoha tika tere o te tarukino "Moxifloxacin" okana me te kopa. He teitei nohanga i roto i te kiko pūkahukahu me mucous bronchi, kiri, me te subcutaneous hanganga, sinuses, aronga inflammatory. kitea te huware, me te whakakī āputa medicament inu i roto i pūmua here, puka free. he tiketike ake i roto i te wē tōna kukū. Fakataha ki tenei raau kitea i roto i moni nui i roto i whēkau te kopa peritoneum wahine whekau taihemahema, me te i roto i te inu peritoneal.

pākia

Medicine "Moxifloxacin" (whakaahuatanga o te raau taero i roto i te raraunga tuhipoka Kei roto ngā mōhiohio) haere te wāhanga biotransformation tuarua. pūnaha excretion whakatinana tākihi me te kōpiro taui i roto i te puka o pūhui sulpho me glucuronide tautauā. E kitea ana te metabolites i roto i te wē. raro atu i taua o te pūhui taketake ratou kukū. Kua whakaaturia Studies e kore enei hua kinonga e whai i te mana ino i runga i te tinana.

Tikanga "Moxifloxacin", e whakaritea i ai reira?

Kei te tūtohutia te tarukino mō pathologies inflammatory hopuhopu i roto i ngā pakeke whakapataritari e microorganisms he tūtohutanga tukunga. I roto i ngā, i te pānuitanga pā ana te exacerbation o te rere Bronchitis, pakohu kakā whakapeka, kakā riro-hapori (meinga e taumahatanga o huakita whakaahua ātete maha i roto i te t. H. te rongoā paturopi). Tikanga "Moxifloxacin" tohutohu mō te whakamahi tūtohutia hoki mate o te kiko ngohengohe me te kiri, ngā hanganga subcutaneous faingataa pāpaka (huaketo rite pai waewae huka), me mate kōtuitui-puku (tukanga Polymorphic, abscesses intraperitoneal me pera atu). Kei te whakaritea ka pneumoniae te medicament i streptococcus ātete ki antibacterials maha, tae atu i te aroaro o taumahatanga ātete ki te rongoā paturopi, e rua, neke atu rānei ngā rōpū o raau taero o te rua o whakatupuranga cephalosporins, macrolides, tetracyclines. Na roto i te tohu hoki ngā pāpaka inflammatory i roto i te whekau papatoiake āhua ngāwari. A, no te E ākina endometritis me salpingitis hoki ki te whakaaro i te tikanga (rite whakaaturia e te piri ki te tarukino "Moxifloxacin" tohutohu mō te whakamahi). pata kanohi i whakaritea mo te pīkaru kitakita, whakapataritari e microorganisms tairongo ki te medicament. Ko reira tika hoki ki te tango ki pūkete te maimoatanga ngā o te ārahitanga pathologies hopuhopu.

Medicament "Moxifloxacin": te inenga me te ara o te whakahaere

Funds whakaritea whekau (waha) a pâmuhia. . Roanga o maimoatanga te medicament "Moxifloxacin", te inenga o nei - 400 mg / ra, i runga i te momo o te mate, me tona pakeke, me te te pānga haumanu kitea rānei:

• Exacerbation o te akoranga Bronchitis - 5-10 ra.
• Hapori-riro kakā - 7-14 ra therapy raupapa (rō-uaua aru e te horomanga waha).
• kiko Soft, kiri (ngāwari), me te pakohu kakā whakapeka - 7 ra.
• A, no te mate kōtuitui-puku (uaua) - 5-14 ra raupapa therapy.
• A, no te uaua pāpaka me ngā hanganga subcutaneous o te kiri - 7-21 ra.
• I roto i te pathologies inflammatory o nga whekau papatoiake - 14 ra.

Mō ētahi atu pārongo, kei roto piri ki te tarukino "Moxifloxacin" ā-ako. e kore kia whakaaetia papa ki te whakahoki ake. Horoia ki te wai ki raro he tika i roto i te rōrahi iti.

whakamahi rohe

Medicine "Moxifloxacin" (pata) kia whakahaere ki tūroro i te tau. E whakaatu ana Practice e tae mai te whakapai ake i te rima o nga ra. I muri e kia tonu koe maimoatanga mo tetahi 2-3 ra. Tūroro i roto i te kanohi pāngia Hare ki te maturuturunga iho e toru nga wa o te ra. Ki te kahore he pānga hoki nga ra e rima kia whakaara i te pātai o te tika o te therapy tātaritanga ranei. Ko te roanga o te maimoatanga tei runga i te akoranga bacteriological me haumanu, me te pakeke o te māuiuitanga.

I tua atu i runga i hoki otinga e whaowhia

Medicament "Moxifloxacin" ako ā-taunaki ana e tomo koutou mo te haora. Te raau kupu e taea e i roto i whakananua, ranei i roto i te puka diluted. He hototahi ki te otinga konutai pūhaumāota 0.9%, te wai mo te werohanga, otinga tēhuka i te kukū o te 10% me te 40%, 20% Xylitol, "ringer". Whakamahia te wai mārama anake. I muri i waimehatanga o te medicament tonu kainga ra i te pāmahana rūma. Kaua ranei hei pupuri i roto i te tikanga pouaka. Ki te te te whakahaerea te whaowhia ki ētahi atu āpiha, ia o e whakahaerea nei wehe.

pānga taha

Nā ki te rongoā maimoatanga "Moxifloxacin" pea ki te whakawhanake i mate fungal, leukopenia, anemia, thrombocytopenia. I roto i ētahi wā, te therapy reira he he hua i roto i te wa prothrombin, te huri i ngä nohanga thromboplastin. I roto i te tahi mau tūroro taea te tarukino meinga mate pāwera, edema laryngeal, urticaria, ru anaphylactic, pruritus, eosinophilia, ohorere. I roto i te wā onge, i reira he Hyperglycemia, hyperlipidemia, hyperuricemia. I roto i te maimoatanga o disorders hinengaro pea. I roto i ngā, kia wheako tūroro te totoa, manukanuka, korekore, depersonalization, moemoea, tauhohe psychotic, tahi e te whakaaro suicidal. pānga taha Common ngā pāhoahoa, whanoke, tremors, te momoe, whakama, disorders reka tūtohutanga, raruraru moe, disorientation. I roto i ētahi wā, i roto i te maimoatanga ki te rongoā kia waimaero ai te ruruku, hukihuki, tahi e ngā faaiteraa haumanu, hypoesthesia, whakararuraru o tikanga o kakara. He maha o tūroro i ähua o kupu, whakarongo, neuropathy piringa, mate wareware, polyneuropathy. A, no te tono topically, kia tupuheke kite noa tona mate. Heoi, whakaaro te muri kei te ki te waiho i te huru molengofuá.

Tākiekina i runga i te pūnaha Cardiovascular

Wāhanga o te pānga te tono o te tarukino "Moxifloxacin" ko te roa QT-wā i roto i te tūroro ki hypokalemia, palpitations, vasodilation, tachycardia. pānga taha Rare ngā takawhita me hypotension, tachyarrhythmias ventricular, syncope. Tino uaua kitea hopu cardiac. Muri te nuinga angamaheni mō takitahi aro ki ischemia whakapeka, bradycardia (hauora nui).

Pānga i runga i ētahi atu pūnaha me whēkau

I roto i ētahi wā, ka taea e te tarukino meinga hāhā o manawa, tae atu huru huangō. He maha o tūroro kitea i disorders i roto i te wahi kūnatu. I roto i ngā, ki te whakamārama o te maimoatanga-tīmata whakapairuaki, ruaki, korere, mamae puku. Āhua e whakaaro torutoru pānga taha hiahia rawakore, dyspepsia, flatulence, köpiro (te kahore hoki erosive), kōroke. Kua tāutuhia ētahi tūroro stomatitis, dysphagia, colitis pseudomembranous. Ka pea whakanui i te therapy i roto i transaminases, pōrearea ate, te whanaketanga o te kakā fulminant, kore ate ārahi ki te ora-te whakawehi. Tino uaua kitea tauhohe waihakihaki bullous (paitini necrolysis epidermal, Stevens-Johnson syndrome). ite ētahi tūroro myalgia, arthralgia, haehae, nui haere uaua oro, tendonitis, uaua ngoikore. Ka taea e ruptures iohere puta i roto i wā onge, rumati, kiwi e ngangau rite ki te hua o te kino ki te pūnaha musculoskeletal. Ka taea hoki e Tūroro i runga i te maimoatanga ki te rongoā kia disorders i kitea ai o te pūnaha mimi. I roto i ngā, tohua maroketanga (whakapataritari korere ranei hekenga i roto i te rōrahi wai pau), pōrearea tākihi, iti hoki. pānga taha Common ngā sweating, mamae nonspecific, ahuatanga. I roto i te thrombophlebitis pea rō-uaua phlebitis ranei.

e kore te wai tautapatia ki te tikanga?

I roto i te rongoā e "Moxifloxacin" contraindications e whai ake:

• māuiuitanga iohere i roto i te aamu i whakawhanakehia rite ki te hua o te rōpū paturopi therapy quinolone.
• Te wātea elongate QT-wā (congenital riro ranei).
• raruraru kawehiko (ngā hypokalemia uncorrected).
• Bradycardia (hauora nui).
• rahunga Heart ki te mahi pana iti i roto i te ana roro maui.
• Maumaui manawataki ngakau (i roto i te hītori).

(Kei roto reihuka tarukino hanganga, na reira nga pathologies e whakaurua i roto i te rārangi whakahuatia), no te reihuka, malabsorption kūhuka-galactose, e kore e tūtohu hoki lactase hē medicament "Moxifloxacin". Ehara i whakaritea tikanga hapu lactating ranei. Papa me te otinga i whakaaetia ki te tūroro ūnga 18 tau. tarukino Manakohia i roto i te take o te hypersensitivity ki nga wae.

take motuhake

hiahiatia tūpato kei roto i te whakarite o te tarukino ki te tūroro ki pokapū abnormalities pūnaha io e auroro ki te whanaketanga o hukihuki. Ko te rōpū mōrearea ngā tūroro ki āhua proarrhythmic. Ko ētahi o ēnei, i roto i ngā, ngā ischemia whakapeka, rawa i roto i te paari, me wahine. mau ano e tūpato i roto i tūroro ki ate cirrhosis. Kia rapua ai inenga whakarerekētanga i roto i te tikanga therapy katoatia e tukupu ana i te kukū o te pāhare pāporo.

Mō ētahi atu pārongo,

whakaatu Practice e te pai noatia te tarukino i roto i ngā tūroro maha. maha whakahau tohunga te taputapu mō pāpaka hopuhopu. Ko e tika ana ki te meka i te tarukino he tōtika āhua nui o te huakita maha tenei. Heoi, i reira he tonu te mōrea o ngā pānga taha, e kua ngā ki te hua faaara "Moxifloxacin" ako ā-ringa. kia tangohia ake Analogs o te raau taero i roto i te take o te hiahia te tākuta takitahi. Whakakapia taea taputapu pērā raau taero rite: "Avelox", "Vigamoks", "Rotomoks", "Moksifur", "Moksin" me etahi atu. A, no te nga pānga kino, he ino koi me te takanga o tohu kahore e i whakaahuatia i roto i te whakarāpopototanga, me rapu e koe te rapaauraa,. A, no te whakamahi i te pata kia karo whakapā ki rahi o kanohi o te tarukino. Ki te tupu tenei, kia rite ki hohoro rite taea e hiahia ana koe ki te nui o te wai. I roto i te take o te tuwhena rawa whakarei ake o ngā pānga taha.

I roto i te mutunga

Ko te tarukino "Moxifloxacin" whakaaro antibacterial feunga puai. I roto i te hononga ki tino tenei e kore e tūtohu reira ki te wahi i whakahaunga o te tākuta. I roto i ngā, āwangawanga reira te maha, me te auau o te tikanga tono. Kaua e nui ake i te inenga. kia kawea i werohia rō-uaua i roto i roto i te ako motuhake e te mema kaimahi tohu ko wai ka taea ki te āwhina, ki te tika. E kore koe kia whaiaro medicate-. I roto i te ngaro o ngā hua o te therapy he tika ki te kite i te tākuta. Just mua ki te whakamahi i te tarukino "Moxifloxacin" kia āta pānui i te tohutohu.