Ko te tarukino "Mikosist": arotake, analogues, utu. Drug "Mikosist": tohutohu mō te whakamahi

tautuhi Drug "Mikosist" ā-ako hei kaihoko antifungal. Ko te whakauru mātātoa o te tarukino mahi fluconazole - he inhibitor whiriwhiri o sterol kōtuitanga i roto i te pūtau fungal. Kōpeke te reira i roto i te pūnaha cytochrome tangata e kore e P450 whakaatu mahi androgenic, he reira whai hua ki te whakapai kanohi ki tukumate o mycosis.

Pharmacokinetics

I muri i medicament-waha rō-uaua ranei "Mikosist" (tohu kaiwhakamahi tenei) pai ki te fluids tinana me te kopa. I roto i te sputum, inu peritoneal me articular, huware, waiu uma kukū rite ki taua tutuki i roto i te wē toto tarukino. Ko te ihirangi o te fluconazole i roto i te inu cerebrospinal i roto i te tūroro ki te meningitis fungal ko e waru tekau ōrau o te kukū i wē i, i roto i te tahuri, he tika hautanga ki te horopeta. A, no te tutuki tono kotahi-rā ki te wha-rima o 90 ōrau ra te kukū taurite. Ki te ki te ra tuatahi tango i te horopeta i te taikaha o te rua ngā wā mua, ka taea e koe te rua o nga ra ki te tae 90 ōrau o te haaputuputuraa taurite. Kotahi tekau ma tahi ki te tekau ma rua ōrau o te here fluconazole ki pūmua wē. I roto i te metabolites toto piringa kore e kitea. tei tino Pharmacokinetics i nga whatukuhu, no te mea excreted te tarukino te nuinga whakaatu ratou, a pā ana ki waru tekau ōrau - tonu. I roto e toru haora o tātari iti te kukū o te taonga kaha i roto i te wē e te hawhe.

Tuhinga hoki

E tūtohu ana ki te whakamahi i te tarukino "Mikosist" piopio, tae atu whānui, ueue, taihemahema, ka tahi atu mau huru o urutomo mate Candida, candidemia, a i roto i te aroaro o te āhuatanga e e hāngai ki te putanga o te piopio. whakaaturia hoki ko te whakamahi o te tarukino hoki te iwi ki te mucosal candidiasis: pharynx; candidiasis-waha, tae atu atrophic, i puta ake i mau niho more; pū kai. Medicine "Mikosist" ā-ako taunaki whakahaere ki tūroro mate i te kiriuhi ua cryptococcal, ranei sepsis, cryptococcosis, mate cryptococcal o te kiri pūkahukahu ranei. Ia tono ano hoki te ārai o te hohokitanga o enei abnormalities i roto i te tūroro ki te AIDS me i te tahi atu te wā o te ārai. Rongoā e whakamahia ana ki te ārai i mate fungal i roto i te iwi ki te pukupuku mārere, i haria rite ki te hua o te radiation hahau ki te hinga raraunga ranei. Ano, whakamahia te tarukino "Mikosist" kei roto i te maimoatanga o fungal mate tapatapa me utumu, mycoses te kōtore hohonu, tae atu paracoccidioidomycosis, coccidioidomycosis, histoplasmosis i roto i tūroro ki ngā pūnaha noa ārai.

Te puka inenga, tākai, hanganga

E rua inenga puka o medicament kua "Mikosist": capsules me otinga mō te whaowhia. E hanga capsules kei roto 50, 100, me 150 milligrams o fluconazole. Ko katoa o ratou gelatin pakeke, me te tinana ma puatakore, a ka rerekē anake i roto i tapo'io te tae: y capsules kei roto 50 milligrams o whakauru kaha, pōtae puru marama 100 milligrams - emerara, 150 milligrams - puru. Ihirangi Ko te papatipu totoka paura ma paura (tata ma) ranei. kai Apatoko ngāue stearate konupora, anhydrous reihuka, te hauhā silicon colloidal, talc, Titanium hāorarua, te witi māngaro, gelatin, poropango Carmine. Capsules kei roto 50 me te 100 mg o fluconazole, kua hokohoko i roto i te pōkai ki tetahi, e rua, e wha nga opupu, e whitu nga wahi ia. Na te hunga e roto i 150 milligrams o whakauru hohe - i roto i te kotahi e rua ranei nga wahi.

otinga e whaowhia e te ahua o te mārama, te huitahi iti purepure ranei wai. Kotahi roto e rua milligrams ia ritamano o te taonga kaha. he wai mo te werohia me te konutai pūhaumāota te wāhanga tuarua. otinga operehia i roto i te karaihe oko e rau milliliters whakanohoia i roto i ngā pouaka pepa. Kei kotahi pōkai kotahi oko.

Me pēhea te ki te tango "Mikosist"? inenga

Ko te horopeta mua o te fluconazole i roto i te mate cryptococcal ko te ra tuatahi o te maimoatanga, 400 mg, i roto i nga ra e whai ake nei - 200-400 milligrams. Ko te roanga o te therapy tei runga i te whakapumautia ako mycological o te miramira haumanu, he reira maha kaua e nui ake te ono - waru wiki. I roto i te kiriuhi ua cryptococcal whakamahi i te rongoā "Mikosist" tohutohu mō te whakamahi tūtohutia hoki tekau - ma rua wiki i muri i ko te hua tauira ako kino o te wai cerebrospinal. AIDS tūroro i muri i te otinga o te maimoatanga tuatahi tohua te mo te ārai o te hohokitanga o meningitis cryptococcal hoki o fariiraa he wā roa tikanga "Mikosist" i te horopeta o kahore iti iho i te rua rau milligrams ia ra.

I roto i te tūroro ki candidiasis tohaina, candidemia me ētahi atu mate Candida urutomo, te tikanga i roto i te ra tuatahi o te tango e wha milligrams o te raau taero, a i roto i te ra i muri mai - e rua rau milligrams rā. I roto i te take o nui horopeta rewena pūnahanaha kia nui haere ki te waru rau milligrams ia ra. kia haere tonu te rongoā mō te iti rawa e rua wiki i muri i te whakakorenga o nga tohu, me te whiwhi i te ahurea tōraro toto. Ki te candidiasis oropharyngeal, tae atu i roto i tūroro ki te mate waimaero, tarukino inenga ia ra ko te rima tekau - kotahi rau milligrams, tango ki reira hei te wā o te whitu - ma wha nga ra. I roto i te candidosis atrophic hua i mau niho more te tikanga whakaritea rōpū rā, e rima tekau milligrams o te tarukino i roto i ngā ki rongoā horoi. Treatment tonu hoki e rua wiki. Hoki atu mate Candida (candiduria, esophagitis, kiri, me te mucosal candidiasis) horopeta ia rā o te rongoā, ko te rima tekau - kotahi rau milligrams, therapy he ma wha - e toru tekau nga ra i.

I roto i te tikanga ki te whakakore i tara candidiasis medicament "Mikosist" whakaaturanga ako ā-tango putawa, i roto i te nui o 150 milligrams. E nehenehe te reira mo wha - marama kotahi tekau ma rua kotahi ki te marama inu kotahi capsule (150 mg) ki te whakaiti i te auau o relapses. E mea pinepine whakaritea hoki candidiasis i tua ki te tarukino "Mikosist" kānara, hei tauira, "Terzhinan", "Clione-D", "Ginezol". Tei runga i te tohu o te mōrea o te mate fungal, mo te ārai o candidiasis taea te horopeta taunakitia rā o te tarukino rerekē i rima tekau ki te wha rau milligrams.

I roto i te take o mycoses te kōtore hohonu Me ai ki te tango i te tarukino i te inenga o te rua rau - wha rau milligrams ia ra mō te rua tau. Ko te roanga o te maimoatanga tei runga i te takitahi me te pikitia haumanu: ki coccidioidomycosis, taea ngā reira i ma tahi ki nga marama e rua tekau-wha, paracoccidioidomycosis - i rua ki te whitu nga marama, histoplasmosis - i toru ki te whitu nga marama.

ture tono

kia teuteu maturuturu rō-uaua kia whakahaere i te tere o te kore neke atu i rua tekau milliliters ia meneti. Kahore he hiahia ki te huri i te horopeta rā, ka whakawhiti tūroro i rō-uaua ki te rongoā ā-waha. He otinga mō te whaowhia he hototahi ki dvadtsatiprotsentnym otinga kūhuka; rongoā Hartman ko Ringer; otinga o te konutai hauwai pākawa waro, pāhare pāporo pūhaumāota i roto i te kūhuka i, te konutai pūhaumāota (0.9%). kia kawea ai e whaowhia i te whakamahi i kete fluconazole noa mō te huhu, te whakamahi i tetahi o nga rongoā e whai ake nei.

pānga taha

Te nuinga o nga tūroro e ka mau te tarukino "arotake Mikosist 'e pā ana ki rau reira he pai. Drug mau tōtika faaore mate fungal engari ka taea e meinga pānga kino. Heoi, i te pūnaha kūnatu ko te mōrea o te whakapairuaki, flatulence, rerekē mahi ate, raruraru ki te tikanga o te reka, korere. Ano, tirohia te tahi mau iwi ki te takanga o pāhoahoa, haurangi, whanoke. mea ratou e kua puta ake taua ari i muri i tango i te raau taero, "Mikosist" hohoro. Reviews o ētahi atu tūroro i roto i ngā mōhiohio e pā ana ki te whanaketanga o te mate pāwera tarukino therapy i roto i te puka o te erythema, ponana, angioedema, urticaria. I roto i te tahi atu ngā pānga taha taea kia tuhia alopecia, fibrillation ventricular, mahi tākihi waimaero, hypertriglyceridemia, hypercholesterolemia, me hypokalemia.

contraindications

I roto i te puka o capsules kore kia whakaritea rongoā ki ngā tamariki i raro i te ono marama o te tau (mo whakaaetia hou ki te whakamahi i te raau taero i roto i te puka o te otinga mō te whaowhia). Kaua e whakamahi i tenei tarukino "Mikosist" lactating wahine (Me wahine hapu ki te tautapa i te reira ki te tiaki), me te iwi ki te tūtohutanga tiketike ki te kai ngā i roto i te hanganga. Ki te hiahia nui haere ki te whakamahi i tūpato ki tūroro ki iti hoki ate / tākihi, ātete o te waikawa ahipirini.

tuwhena rawa

"Mikosist" tuhia take o tuwhena rawa tarukino. Reviews o te iwi nei ka mau te tarukino i roto i pota nui, tohu te whanaketanga o te korere, whakapairuaki, ruaki. I roto i ngā take kino, i reira ko te ahua o hukihuki, whanonga Wairau, moemoea. He tangata ki tohumate o tuwhena rawa kia tangohia ki hōhipera, te wahi e kia hanga lavage pekitīlia ki a ia, tātari, diuresis takoha, therapy symptomatic.

"Mikosist" "Fluconazole" ranei: i te mea pai?

Heoi ka ui pinepine te pātai i te tūroro. I roto i te meka, ko te taua raau taero e rua, ka taea e tatou te mea e he ōrite ratou. Ko te rerekētanga anake ko e te tarukino "Mikosist" hanga te kamupene Hungarian ho'oraa "Kiriona Richter", i "Fluconazole" - te faaineineraa o te production kāinga. O te akoranga, kua he pānga tika i runga i te utu o ngā rongoā tenei. Te kōwhiri i te mea ki te hoko - "Mikosist" ranei "Fluconazole" - he tokomaha hiahia ki te tarukino, i te mea iti. Oia mau, te rerekētanga nui i roto i te utu. Na, mo te tākai o "Mikosista" (kotahi capsule kei roto 150 milligrams o fluconazole) whai koe ki te utu i te toharite o 295 moni, i te mōkihi taua "Fluconazole" utu 8-20 anake moni. Ko te utu toharite o te pounamu 100 ml o te otinga mō te whaowhia "Mikosist" ko 311 moni.

Na i runga i te āhuatanga pharmacological o nga taero e rua, he ratou tata ōrite, ka taea te kite i te rerekētanga anake e te tere o te absorption: kia rite ki raraunga e wātea ana, i uru te kukū mōrahi i roto i te tinana "Fluconazole" Kei muri i 1-2 haora i muri i te tono, me "Mikosista" - 0.5 -1,5 haora. Heoi, e kore tūroro katoa whakautu ki te rongoā e rua ōrite. e kore e ētahi kite i tetahi rerekētanga i waenganui ia ratou, i te whakapono i te whakamutunga e, tei te kounga i runga i te utu, i te tikanga e ko atu te utu, te pai te tarukino. Ka taea e maha e kitea e koe arotake i roto i nei titau wahine e muri i tango i te "Fluconazole" piopio hoki ka haere mai, engari te "Mikosist" whakaaetia ki te pehea e o reira tūturu. I roto i tetahi take, ko te whiriwhiri ko koutou.

analogs

I tua atu ki "Fluconazole", i reira e te tahi atu rongoā e taea te whakakapi i te tarukino "Mikosist". Analogs medicament he whakauru rite kaha te taonga taua, e pai māngai. I roto i te puka o capsules mo te maimoatanga o te rewena me ētahi atu mate fungal, ka taea e koe te whakamahi i "Diflucan" taero "Flucostat", "mikomaks" me etahi atu. He tikanga whai hua ko "Mikoflyukan" (papa). "Mikosist" i enei analogs rerekē katoa e tohu pērā i bioavailability, hawhe-ora, te tere o te absorption.

taunekeneke tarukino

He mea tika ki āta aroturuki i te wa prothrombin i roto i te tūroro te whiwhi fluconazole me autaki anticoagulants rōpū coumarin, no te mea i reira te mea he mōrearea o te whakanui ake i te VWP. A, no te concomitantly ki sulfonylureas tarukino "Mikosist" kia roa te hawhe-ora o ratou, kia hiahia koe ki te whakaaro i te taea o te suka. I roto i te take o te fluconazole me tiritiri phenytoin kia hauora nui tohu o hua o te kukū whakamutunga, Na, ki te tika ngā fariiraa i te horopeta kia iti. Fakataha ki te whakauru tikanga "Mikosist" a ka rifampicin kia tohua hekenga i roto i te kukū o te fluconazole reira horopeta "Mikosista" hiahiatia ki te whakapiki ake i. Ko te whakamahi ngā o te pārōnaki azole ki te medicament i roto i ngā ki terenadinom contraindicated, rite taea whakawhanake nui, arrhythmia ora-te whakawehi. Ki te tangohia e koe rongoā "Mikosist" tahi ki cisapride, taea whakaatu tauhohe houhou i runga i te wahi o te ngakau, tae atu tachycardia ventricular. Ki te whakamahi tukutahi o fluconazole me theophylline heke te auau whakawātea toharite i wē o te toto whakamutunga, a na reira e faarahi i te tūponotanga o te whanaketanga o ona pānga paitini, me te tuwhena rawa.

Ara

Kia haere tonu maimoatanga ki "Mikosist" tae noa ki te murunga haumanu, me te hematological. he mahi wehe, ki relapses korenga atu taimi halá, o te therapy. Ka rite ki kua whakahuatia, tūroro ki iti hoki tākihi kia whakamahi i te tarukino ki tūpato mōrahi, no te mea kua excreted reira te nuinga i te tākihi. kia hanga inenga i roto i te maimoatanga wā roa-, tango ki pūkete te CC. Taime fluconazole tā pānga paitini i runga i te ate, na ko reira tika ki te aroturuki i te mahi o tenei tinana. Ki runga ki te rapunga o pāpaka tohumate kia mutu rongoā.

Tūroro i runga i te whakamārama o "Mikosist" kua tikanga kitenga onge tauhohe waihakihaki exfoliative, pērā i paitini necrolysis epidermal me Stevens-Johnson syndrome. He nui ake e pängia ana ki te putanga o tauhohe kiri nui tūroro ki neoplasms mārere me AIDS ka whakamahi i teuteu kei roto fluconazole. Ki te i roto i te maimoatanga o te mate fungal ausia puta te hunga ponana, ki te tarukino e hiahia ana koe whakakore. Ki te wheako koe ponana i roto i te iwi ki te mate fungal urutomo nahanaha ranei kia whakakaha te tākuta mātakitaki me te whakakore i te raau taero i roto i te kaupapa e ka whakawhanake erythema multiforme, pāpaka bullous ranei. I roto i te maimoatanga, rongoā "Mikosist" (arotake whakau reira) kia meinga whanoke, kia hiahia tūroro ki te kia rawa tupato ka mahi ki te tikanga me te whakahaere o waka.