Ko te tarukino "salofalk": analogs me tohutohu mō te whakamahi

Kei te aro te tinana tangata ki te momo o mate, ohie, me te matatini, puta noa i tona ora. Matara i te i te tata tino i roto i te raupapa o ngā raruraru hauora noho mate whēkau inflammatory. Ki te whawhai ki a ratou ki te whakawhanake i tētahi maha o rerekē rongoā ki te mau parau tumu rerekē o te mahi.

Taonga mesalazine Ko te wähanga tino o te rōpū makona nui o ngā rongoā ( "salofalk" analogs) ki te aro tauwhāiti mate whēkau inflammatory.

Composition "salofalk", pharmacodynamics

Ka rite ki whakahuatia mua, te whakauru matua kaha he mesalazine medicament. Ka rite ki pŭpŭ tauturu tavini he maha o ngā wāhanga, i ngā, pērā i te konutai pākawa waro, glycine, povidone, microcrystalline cellulose, silicas, me Titanium, konupūmā stearate, te konutai croscarmellose, hypromellose matua copolymer butylmethacrylate.

inhibits "Salofalk" (granules, papa, suppositories, whakatārewatanga) (depresses) nga tukanga o te neutrophil me lipoxygenase kōtuitui i roto i te tangata prostaglandins me leukotrienes. Ko te taonga kaha te whakaiti i te auau o te hekenga, phagocytosis me degranulation o neutrophils, te whakaiti i te secretion o lymphocytes. I tua atu, he ahei o here Radicals free a muri whakangaro ratou te medicament, i.e. whakaaturia pānga antioxidant. mesalazine ahei o here ki Radicals free i hanga i ngā momo hāora urupare hoki.

Tuhinga mō te whakamahi

Ko te wāhi matua i roto i i kitea te whakamahi o "salofalk" - he maimoatanga mō te colitis ulcerative me te mate o Crohn.

Ko te mate tuatahi ko kore i te tukanga inflammatory ma'i ano haamaramaramahia te natura. meinga Ko tōna whanaketanga e te pāhekoheko o ngā āhuatanga ira me ngā āhuatanga taiao.

mate o Crohn taea te āhuatanga rite ma'i mumura granulomatous o te wahi gastrointestinal. Tenei tukanga taea te hopu nga wahi katoa o te pūnaha kūnatu, pānga reira ngā papa katoa o te ngongo kūnatu. pea te hopearaa e kore ko te whanaketanga o te lymphadenitis, ulceration me te scarring o taiepa whēkau.

tuku tarukino Puka

Manufacturers whakahere ratou kiritaki te tarukino "salofalk" (rite tenei te faatura e rerekē i roto i) i roto i te torutoru momo rerekē o te hanga.

I roto i te puka papa e taea i roto i 250 500 ranei mg o te wāhanga hohe matua - mesalazine. I roto i te kotahi paihere taea roto i 500 mg 1 go o te taonga matua ranei. E wātea ana i roto i te rua toketaá hoki te medicament i te puka o suppositories (suppositories mō te whakahaere rectal) - 250 me 500 mg o te wāhanga matua. taea hoki te hokona i roto i pharmacies me pahuka i whakatārewatanga hoki whakahaere rectal. Ko te whai hua tino mo ia puka tuku manawanui takitahi e te tauturu ia whiriwhiri koe i te tākuta te rongoā.

papa dosing talena

inenga Paerewa mō te pakeke - toru nga wa o te ra 500 mg. Ki te pāngia ki te tohu nui o te mate, te taote e haere ana kua te tika ki te whakapiki ake i te horopeta ki 3-4 g ia ra. Ko te akoranga o te therapy kia muri i te 2 ki te 3 marama. Ki te tangohia te rongoā kei rite te mehua ārai, kua mahi i te reira e te kaupapa paerewa (1.5 g i roto i toru werohanga i roto i te ra).

tūroro o muri 'Taupānga salofalk "kaiwhakamahi (kia rerekē analogs i roto i te inenga talena) taunaki ana ki te whakarato i roto i runga i te taimaha o te tamaiti. Pēpi ki te taimaha tinana kore rawa 40 kg, whakatakoto te rata 250 mg o te tarukino toru nga wa te ra. Ki te taimaha o te tamaiti nui 40 kg, whakaatu reira te inenga taua rite hoki ngā pakeke: 500 mg toru nga wa o te ra.

E tangohia pai papa i muri i te otinga o te kai, e kore e tararua me te inu nui o inu (he pai te wai).

Ko te kaupapa o te granules

whakaritea ana tēnei puka tuku o te tarukino "salofalk" (granules) e te rata haere rawa takitahi, e hāngai ana i runga i te pikitia haumanu katoa o te hauora o te manawanui. I roto i te nuinga o te wā i roto i te exacerbation o colitis ulcerative whakaritea te manawanui e no te farii i te horopeta o 500 mg 1 g ranei e toru nga wa i roto i te ra (t. E. Ko te rōrahi o ia rā o te medicament ko i 1.5 ki te 3.0 g). Ka taea e koe te tango i te horopeta kotahi kotahi 3 peke. Ki te ko te manawanui i roto i murunga, "salofalk" tango i te horopeta o 1.5 g ia ra: e taea te wehea te reira ki 3 pota tangohia ranei katoa o te tarukino i kotahi.

Ki te korero tatou e pā ana ki te exacerbation o colitis ulcerative i roto i ngā tamariki (i 6 tau, me te pakeke), whakatakoto te rata haere te tarukino i te tere o 30-50 mg mesalazine ia 1 kg o taimaha. e tangohia horopeta katoa kia i tetahi wa wehea ki 3 pota puta noa i te ra ranei.

kia hoatu nga granules i runga i te arero, me te, kahore ngangau, horomia ake. Te raau e inu nui o fluids. Ki ko i te pānga haumanu granules ātete kia tangohia wā me ngā wā katoa. te tikanga mate atamira whakapeka o colitis ulcerative i roto i 2-3 marama, iti ake manakohia horopeta ia rā ki te 1.5 g ia ra.

Taumu'a me te aratau o tono o suppositories

E taunaki ana "Salofalk" (kānara) ako ā-he inenga o 500 mg (1 rectal pire tou 500 mg 2 ranei - 250 mg) e toru ngā wā i te ra. Ki te te mate i roto i te wā whakapeka, e taea te rererua te horopeta ia rā. Ki te whakaritea te manawanui ko te akoranga roa o te therapy ranei ūnga fariiraa - pono prophylactic (ārai matahoki), te horopeta mua i roto i tenei take, ko te 250 mg (1 rama) e toru ngā wā i roto i te ra.

Hoki tūroro teina tei inenga i runga i te taimaha tinana. Tamariki kotahi iti iho i te 40 kg "salofalk" (kānara) tohutohu mō te whakamahi regulates whakarite ½ inenga mo te pakeke, t. E. 250 mg toru nga wa o te ra. Ki te nui taimaha o te tamaiti 40 kg, ko te whakaritea ai ki te inenga tarukino rite hoki tūroro pakeke (e toru ngā wā i te ra 500 mg).

whakatārewatanga rectal

Drug "salofalk" - whakatārewatanga he wātea i roto i ipu whakaratohia hoki whakahaere rectal. whakamana ana te tukanga e kotahi i roto i te ahiahi i mua i te taotoraa. tūtohutia te manawanui mua ki whakahaere o te tarukino te ki te tuku i te paru. whiriwhiri te nui rā o te tarukino e hāngai ana i runga i te taimaha o te manawanui (i roto i ngā o te 30-50 mg / kg). Ki te he nui te mate ranei kei roto i te tukanga o te nui haere, te horopeta mōrahi i roto i te ra e taea tae ake ki te 3 tau ki te ārai i ngā tohunga hohokitanga te tikanga tūtohu tango "salofalk" waha (papa). I roto i tenei take i te horopeta (rā) e whakaritea ana hoki ki te taimaha o - 15-30 mg / taimaha tinana kg. tūtohutia katoa rōrahi rā o rongoā puta noa i te ra e ki te kia wehea ki e rua ngā wāhanga.

Contraindications ki te fariiraa i "salofalk"

contraindicated - (he kahore okotahi analogues) te mo te iwi ki te hypersensitivity ki te wāhanga matua, me te mau pŭpŭ tauturu o te raau taero Whakamahia o te tarukino "salofalk". Ko te tautokohia ki te whakarite papa ki ngā tamariki i raro i te 3 tau o tau, granules - ki-tau 6-tawhito. e kore koe e whai ki te tango i rongoā ki te mamae manawanui i kino iti hoki tākihi ate ranei.

Kaua e whakarite "salofalk" iwi e whai i te haafifi i ki te whakawhanake toto, tini o nga mate pūnaha hematopoietic. Mate ana i te hemorrhagic diathesis āhua o mate whewhe o tetahi wahi gastrointestinal kore e hoki tango rongoā i runga i te pūtake o te mesalazine.

Ko te medicament Kāore granules whakahaere ki tūroro mate i phenylketonuria (mate tuku e pā ana ki pākia waimaero o te phenylalanine arata'i ki kino pāpaka CNS i te puka o te hauātanga hinengaro).

Ki te whakaaro ki nga wahine hapu, me te lactating, kia te whakamahi o te raau taero i roto i te 3 marama tuatahi o te hapūtanga, ka whakatikaia e tohu tino. I roto i 2-3 trimesters whakarite "salofalk" he taea anake i roto i te wā, no te ngoi ana te pānga pai kiia i runga i te hauora o te wahine te mōrearea taea hoki te tamaiti. E ai ki te whakaaturanga taua he e manakohia ana ki te tono i te granules 'salofalk "hohipera. Heoi, ki te he korere te tamaiti, he mea e tika ana ki te whakarere i ū. A i roto i te whānui, optimally whakaritea i mua i te tīmatanga o te hapūtanga, mutu tango "salofalk" ranei, i te iti rawa, whakaiti i te horopeta riro.

pānga taha pea

pānga te taha e tata tetahi tarukino. He ko he okotahi, me "salofalk" (ritenga Russian rite te pai). CNS pānga taha he tohu taea rite pāhoahoa, whanoke, tremors, tinnitus, korekore, haehae, paraesthesia. Ka taea e wahi gastrointestinal urupare ki te whakamahi o "salofalk" i te mamae i roto i te puku, bloating, korere, whakapairuaki, ruaki. whanaketanga pea o kakā, te huri i ngā uara transaminase ate. kia riro manawa-iaia pūnaha tachycardia, te pēhanga toto tātāu (hyper- hypotension ranei), uma mamae, dyspnea.

I roto i ētahi wā, ka taea te rongo tūroro i runga i te whanaketanga o myalgia, arthralgia. I tua atu, ka taea e te tarukino meinga anemia, leukopenia, thrombocytopenia, anuria, oliguria, hematuria, crystalluria.

O te maha o mate pāwera ko taea minamina, ponana kiri, erythema, bronchospasm, pericarditis me myocarditis. I roto i te tūroro ki te hypersensitivity kia whakawhanake mate pērā i pauku interstitial, syndrome nephrotic, wāhanga whakapeka o pancreatitis ki mesalazine. I roto i te rōpū motuhake o tūroro "salofalk" (rite ki tona rite pai) ai tohu rite ki te syndrome o erythematosus lupus pūnahanaha.

rongoā analogues

Ko te "salofalk" rahinga rawaka o ngā rongoā analogues o te wāhanga kaha matua. Pehea e taea, hei tauira, te whakakapi "salofalk" - kānara? Analogues, e he maha nga ngākau nuitanga o kiritaki me ngā kaiwhakarato tiaki hauora e whakaritea - ko suppositories "Pentas" me "Samezil". Ēnei rongoā matua whakauru kaha he mesalazine, na to ratou pānga pharmacological rite i runga i te tinana tangata.

"Mesakol" - tetahi atu tairitenga "salofalk" whakamahia whānuitia (i roto i granules, papa).

Haunga wae tairitenga mahi, i reira he he rōpū nui o raau taero e te hunga rite i roto i te pānga haumanu. Ka taea e ēnei taero kawe humarie "Azathioprine" me "Alginatol", "hydrocortisone" me "Dexamethasone" "Diprospan" me "Irmalaks", "prednisolone" me "Sulfasalazine". Ko te rārangi haere i runga i.

tūtohutanga motuhake

I mua i te tīmata koe maimoatanga me te wā maimoatanga, me i muri ona kaiwhakarato whakamutunga tūtohu ki te tango i whakamātautau toto me te mimi noa. i mua hoki i te maimoatanga me te i roto i te tukanga ko reira tika ki te aroturuki i te tawhā o te kāwanatanga mahi o te ate. Kei te pai mahi Aroturuki i muri i te 14 ra i muri i tomokanga o therapy, a ka 2-3 tetahi wa i wā o 4 wiki. Ki te mea ko nga hua whakamātautau i roto i rohe noa, kawea aroturuki rangahau i nga 3 marama. Ki te ka kitea rawatia ake etahi ahua o te ine i te tātari, he mea e tika ana ki te kawe i roto i whakamātautau mana tonu.

I roto i te whakarite o tetahi ahua o te rongoā "salofalk" (kānara, analogues o papa, granules, te aukati) ki tūroro mate i huangō arahau, e hiahiatia ana te rata te ki āta aroturuki i te huru o te tūroro i roto i therapy. Ki te mea he hītori o te manawanui puta te taea o ngā pānga taha, ka tango "Sulfasalazine" āhua o te hauora o taua iwi kia aroturuki āta i roto i te wāhanga tuatahi o te maimoatanga "Salofalk." Ki te faaite mai e ratou he tauhohe ātete whakapeka (haehae, mamae puku, hikaka, kirika), kia mutu tonu te whakamahi o te raau taero.

A, no te peia e mahi ana mahi e rapua e tauhohe whakamātau tinana tere tiketike, tūroro fariiraa i "salofalk" ranei, kia kia tino tupato.